You Searched For: Hytest Ltd

Catalog Number: (103011-374)

Supplier: Anaspec Inc

Description: Environment-sensitive dye for studying membrane and protein structures

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Catalog Number: (103006-368)

Supplier: Anaspec Inc

Description: BNP-45 represents the 45 amino acids at the C-terminus and the mouse BNP-45 has all the amino acid residues thought essential for NP bioactivity, although sequence identity when studied with other BNP hormones (rat, 64%; dog, 53%; pig, 50%; and human, 44%) was clearly less than the identity among ANF hormones. The threonine 81 residue at which a protein kinase C phosphorylation site is present in the putative mature mouse BNP-45 hormone is not conserved in the rat sequence.
Sequence:SQDSAFRIQERLRNSKMAHSSSCFGQKIDRIGAVSRLGCDGLRLF (Disulfide bridge:23 - 39)
MW:5040.8 Da
%Peak area by HPLC:≥95%
Storage condition: -20°C

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Supplier: Anaspec Inc

Description: The native peptide KKALRRQETVDAL (60249-1) is a selective substrate for Ca2+/calmodulin-dependent protein kinase (CaMK). The fluorescent and biotinylated peptides are used to design assays for CaMKs.
Sequence:KKALRRQETVDAL
MW:1527.8 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: (103009-986)

Supplier: Anaspec Inc

Description: This peptide is derived from bovine peripheral myelin P2 protein amino acid residues 53-78. It is neuritogenic, inducing experimental autoimmune neuritis (EAN) in Lewis rats.
Sequence:TESPFKNTEISFKLGQEFEETTADNR
MW:3019.9 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103010-588)

Supplier: Anaspec Inc

Description: Histone deacetylase (HDAC) enzymes act as transcriptional repressors of genes through the deacetylation of lysine residues on histone proteins

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Catalog Number: (103010-236)

Supplier: Anaspec Inc

Description: MMP-7 (matrilysin, PUMP) is involved in biological events, such as tissue remodeling, cell proliferation and host defenses.

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Catalog Number: (103008-178)

Supplier: Anaspec Inc

Description: This Histone 3 peptide is acetylated at lysine residue at 9th position. In a glioblastoma xenograft expressing a O6-methylguanine-DNA methyltransferase (MGMT), increased H3K9-ac was observed in correlation to histone acetylation and MGMT upregulation, thus demonstrating a mechanism driven by chromatin-mediated MGMT upregulation in potentially directing epigenetic therapies to influence the mechanisms of resistance development in glioblastomas.
Sequence:ARTKQTAR-K(Ac)-STGGKAPRKQLATKA
MW:2597 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103007-256)

Supplier: Anaspec Inc

Description: This synthetic peptide corresponds to ß--Amyloid (1-40) with an additional cysteine at the C-terminus.
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVC
Molecular Weight: 4433 Da
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

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Catalog Number: (102996-382)

Supplier: Anaspec Inc

Description: This peptide is PACAP (1-38) with a Biotin label on its N-terminus. Pituitary adenylate cyclase-activating polypeptide (PACAP), a member of the vasoactive intestinal peptide/secretin/glucagon family, has an amino acid sequence identity of 68% with vasoactive intestinal polypeptide (VIP). PACAP38, derived from a 176-amino acid precursor (preproPACAP), is a 38-amino acid peptide discovered as an ovine hypothalamic neuropeptide. The amino acid sequence of PACAP is identical in all mammals, and in species such as chicken, frog, salmon, only 1–3 amino acids are different. It is abundant in both the central and peripheral nervous systems and exerts a variety of effects. PACAP in pancreatic islets may play a parasympathetic and sensory neurotransmitter role. PACAP stimulates insulin secretion from islets in a glucose-dependent manner at femtomolar concentrations, acting as an insulinotropic factor. PACAP and VIP are two multifunctional neuropeptides modulating innate and adaptive immunity. VIP/PACAP protect T cells from activation-induced cell death through down-regulation of Fas ligand. PACAP immunoreactivity has been shown in nerve fibers innervating the intrapancreatic ganglia as well as the islets of Langerhans in pancreas. PACAP (1-38) is more active than VIP in stimulating adenylate cyclase EC50=7 nM.
Sequence: Biotin-HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH2
MW: 4761.6 Da
% Peak area by HPLC: 95
Storage condition: -20° C

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Catalog Number: (103008-276)

Supplier: Anaspec Inc

Description: This peptide corresponds to amino acids 26 to 46 of human histone H3. It is dimethylated at lysine-36, followed by a biotinylated lysine. The methylation of histone H3 at lysine 36 (K36) has recently been shown to be associated with RNA polymerase II (Pol
Sequence:RKAAPATGGV-K(Me2)-KPHRYRPGTV-K(Biotin)
MW:2630.1 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103003-052)

Supplier: Anaspec Inc

Description: This peptide is a major constituent of protein deposits identified in the Islets of Langerhans of patients with noninsulin-dependent diabetes mellitus.
Sequence: KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY - NH2 (Disulfide bridge: 2 - 7)
MW: 3903.3 Da
% Peak Area by HPLC: ≥ 95%
Storage condition: -20°C

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Supplier: Anaspec Inc

Description: This peptide is beta-amyloid (1-42) N-terminally truncated. It is the non-pyroglatamate form of beta-Amyloid (3-42). N-terminally truncated pyroglutamate-modified beta-Amyloid forms such as Aß(3-42) and Aß (11- 42) have been described as major compounds in the senile plaques. Pyro-Glu modified beta-Amyloid forms are more resistant to degradation, show higher toxicity and have increased aggregation propensity compared to non-modified beta-Amyloid.
Sequence: EFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Molecular Weight: 4327.9 Da
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

Supplier: Anaspec Inc

Description: This hypophysiotropic peptide was isolated from human hypothalamic-hypophysial tissues. Within this 1 to 29 amino acid GRF fragment, amino acids 13 to 21 are more important than 24 to 29 for high affinity receptor binding. Structure–activity studies show that hpGRF(1–29)-NH2 has full intrinsic activity and potency in vitro as the full length GRF in stimulating growth hormone release. Human GRF (1-29) has a high degree (>93%) homology with procine, bovine and ovine GRF (1-29)-NH2.
Sequence: YADAIFTNSYRKVLGQLSARKLLQDIMSR-NH2
MW: 3357.9 Da
% Peak area by HPLC: 95
Storage condition: -20° C

Catalog Number: (103006-536)

Supplier: Anaspec Inc

Description: This peptide is histone H4, amino acids 1 to 21. It is acetylated at Lys-8 and at the N-terminus with a C-terminus GG linker, followed by a biotinylated lysine. The acetylation of histone H4 causes structural changes that amplify the binding of transcription factors to their recognition sites within the nucleosome.
Sequence:Ac-SGRGKGG-K(Ac)-GLGKGGAKRHRKV-GGK(Biotin)
MW:2644.1 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103008-316)

Supplier: Anaspec Inc

Description: This peptide is Histone H2A amino acid residues 1 to 22 with a C-terminal Gly followed by a biotinylated lysine. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:SGRGKQGGKARAKAKSRSSRAG-GK(Biotin)-NH2
MW:2612 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103010-288)

Supplier: Anaspec Inc

Description: The SensoLyte® Plus 520 MMP-1 Assay Kit is designed for specifically detecting MMP-1 activity in biological samples which may contain multiple MMPs, such as culture medium, serum, plasma, synovial fluid, and tissue homogenate. A specific anti-MMP-1 monoclonal antibody is used in combination with an MMP fluorogenic substrate, 5-FAM/QXL®520 FRET peptide. The fluorescence signal is monitored at Ex/Em=490 nm/520 nm upon MMP-1-induced cleavage of the FRET substrate. Ample materials are provided to perform 96 assays in a 96-well format.

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