Catalog Number: (103006-990)

Supplier: Anaspec Inc

Description: This peptide is beta-Amyloid (1-15), human sequence.Sequence: DAEFRHDSGYEVHHQ
Molecular Weight: 1826.9 Da
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

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Catalog Number: (103010-388)

Supplier: Anaspec Inc

Description: Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components. MMP-10 (stromelysin 2) is involved in several pathological conditions, such as cancer, arthritis and wound healing. MMP-10 is secreted as zymogen with a prodomain, a catalytic domain, a hinge region, and a hemopexin-like domain. It can activate other MMPs such as MMP-1, MMP-8 and degrade a variety of substrates, including gelatin, collagens III, IV and V, fibronectin, aggrecan

This recombinant human MMP-10 was expressed as a pro-enzyme enzyme from its DNA sequence7 transfected into a mouse myeloma cell line, NS0. The apparent Mr on SDS-PAGE is 58-kDa. Incubation with 1 mM APMA at 37°C for 1-2 hours will activate pro-MMP-10. Its activity can be measured by FRET peptides

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Catalog Number: (103009-750)

Supplier: Anaspec Inc

Description: This peptide is based on amino acids 73 to 83 of histone H3. Lysine 79 of Histone H3 (H3K79) has been identified as a residue for acetylation or methylation.Related Peptides: [Lys(Ac)79]-Histone H3 (73-83), H3K79(Ac), Cat# 65438 [Lys(Me3)79]-Histone H3(73-83), H3K79(Me3), Cat# 65439[Lys(biotin)79]-Histone H3 (73-83), H3K79(biotin), Cat# 65440
Sequence:EIAQDFKTDLR
MW:1336.5 Da
% peak area by HPLC:95
Storage condition:-20° C

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Supplier: Anaspec Inc

Description: Myelin Oligodendrocyte Glycoprotein (MOG) is a member of the immunoglobulin superfamily and is expressed exclusively in the central nervous system (CNS). Although MOG protein constitutes only 0.01-0.05% of the CNS myelin proteins, it was demonstrated that MOG protein is a crucial autoantigen for multiple sclerosis in humans and experimental autoimmune encephalomyelitis (EAE) in rodents and monkeys

The sequence (Accession # NP_034944) corresponding to the extracellular domain of mouse MOG along with a 6x His tag was expressed in E. coli. The recombinant mouse MOG (M-rMOG) was purified from urea denatured bacterial lysate using immobilized metal affinity chromatography (IMAC). The molecular mass of the recombinant mouse MOG is 14.2 kDa

Catalog Number: (103005-926)

Supplier: Anaspec Inc

Description: Aggrecanases belong to the ADAMTS (A disintegrin and metalloprotease with thrombospondin motif) family of proteases. Aggrecanases cleave aggrecan, the major structural component of cartilage. Aggrecanase-1 (ADAMTS-4) is a major aggrecanase in human osteoarthritic cartilage.
This FRET peptide was used in an ADAMTS-4 (Aggrecanase-1) assay. Ex/Em = 340/420 nm.
Sequence:Abz-TEGEARGSVI-Dap(Dnp)-KK-NH2
MW:1644.8 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103003-714)

Supplier: Anaspec Inc

Description: The peptide, corticotropin releasing factor (CRF) was first isolated in the mammalian brain that regulates the hypothalamic-pituitary-adrenocortical axis. It also plays a key role in modulating the endocrine, autonomic, and behavioral responses to stress and cardiovascular, gastrointestinal, and immune activities.
Sequence: SEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEII-NH2
MW: 4757.5 Da
% Peak area by HPLC: 95
Storage condition: -20° C

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Catalog Number: (102996-096)

Supplier: Anaspec Inc

Description: This is a 38 residue inactive big endothelin-1 intermediate that gives rise to a shorter active peptide produced in vascular endothelial cells.
Sequence:CSCSSLMDKECVYFCHLDIIWVNTPEHIVPYGLGSPSRS (Disulfide bridge: 1-15 and 3-11)
MW:4384.1 Da
%Peak area by HPLC:≥95%
Storage condition: -20°C

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Catalog Number: (103010-546)

Supplier: Anaspec Inc

Description: Cathepsin K is the lysosomal cysteine protease involved in bone remodeling and resorption, also having a potential as a drug target in autoimmune diseases and osteoporosis

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Catalog Number: (103011-072)

Supplier: Anaspec Inc

Description: QXL® 670 dyes are optimized quenchers for Cy5 and Cy5-like fluorophores such as HiLyte™ Fluor 647.

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Supplier: Anaspec Inc

Description: This peptide prepared by neutralizing the TFA salt form of Aß (1-42) with a dilute sodium hydroxide solution has superior solubility and fibrillogenesis properties, and the fibrils are equally neurotoxic.
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
MW: 4514.1+23 Da
Molecular Weight: 4514.1 + 23
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

Catalog Number: (103003-186)

Supplier: Anaspec Inc

Description: This peptide is amino acids 46 to 61 fragment of the hen egg lysozyme (HEL). Lysozyme is anti-bacterial enzyme found in high concentration in the egg white. HEL was used in MHC related studies, and tested as a part of antimicrobial vaccines.
Sequence:NTDGSTDYGILQINSR
MW:1753.9 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (102996-442)

Supplier: Anaspec Inc

Description: This is a fluorescent Thrombin substrate, Abs/Em=380/500 nm.
Sequence:fPR-AFC
MW:629.5 Da
%Peak area by HPLC:≥95%
Storage condition: -20°C

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Catalog Number: (103007-382)

Supplier: Anaspec Inc

Description: This peptide is a control for the RGDS Fibronectin Active Fragment and other RGD-related peptides. Asp3 is replaced by Glu3 in RGDS peptide changing its properties to inhibit integrins and proteins of extracellular matrix binding.
Sequence:RGES
MW:447.5 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103011-118)

Supplier: Anaspec Inc

Description: Congo Red, UltraPure Grade, Early diagnosis and classification of amyloid deposition, Molecular Weight: 696.7, Spectral Properties: Abs/Em = 497/NA nm, Solvent System: Water, CAS number: 573-58-0, Molecular formula: C32H22N6Na2O6S2, Physical State: Solid, Storage: -20 deg C, Size: 1 g

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Catalog Number: (102999-434)

Supplier: Anaspec Inc

Description: All the HCl salt forms of Aß (1-40), Aß (25-35) and D-Ser26 Aß (25-35), take the ß-structure within a few hours in PBS. They form fibrils, exert toxic effects on hippocampal cultured neurons and suppress MTT reduction activity of non-neuronal (HeLa) cells without cytotoxicity.
Sequence: GSNKGAIIGLM - HCl
Molecular Weight: 1060.3+36.5 Da
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

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Catalog Number: (103007-624)

Supplier: Anaspec Inc

Description: This is a myristoylated PKCζ pseudosubstrate-derived ζ-inhibitory peptide (ZIP) found to inhibit an atypical type of Protein Kinase C ζ (zeta). It has been shown to also interact with PKC family isoforms and disrupt conventional PKC targeting and translocation leading to physiological memory impairment. The sequence corresponds to the pseudosubstrate region of the N-terminal regulatory domain that maintains the enzyme in an inactive form in the absence of activator. The pseudosubstrate peptide has also been shown to be a competitive inhibitor of PKCζ in neurons. This peptide was also used to demonstrate that PKC ζ is involved in the regulation of integrin-dependent adhesion and chemotaxis of intact human neutrophils.
Sequence:Myr-SIYRRGARRWRKL
MW:1928.5 Da
% peak area by HPLC:95
Storage condition:-20° C

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