You Searched For: Hytest Ltd

Catalog Number: (103007-100)

Supplier: Anaspec Inc

Description: This amino acids 22 to 27 fragment is a modification of the human islet amyloid polypeptide hIAPP (NFGAIL) with N-methylation of the amide bonds at G24 and I26. The introduction of two N-methyl rests in the amyloid-core-containing sequence NFGAIL converts this amyloidogenic and cytotoxic sequence into non-amyloidogenic and non-cytotoxic peptide. The peptide is able to bind with high-affinity full-length hIAPP and to inhibit its fibrillogenesis.
Sequence: NF-(NMe-G)-A-(NMe-I)-L
Molecular Weight: 661.8 Da
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

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Catalog Number: (103006-274)

Supplier: Anaspec Inc

Description: This product contains 0.03 mg (net) of the 32 CEF peptides for a total of 1 mg in one vial. Used in the stimulation of IFNγ release from CD8+ T cells in individuals with defined HLA types, these epitopes are useful in applications such as ELISPOT, intracellular cytokine and CTL assays.
% peak area by HPLC: ≥ 95
Storage condition: -20°C

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Catalog Number: (103007-252)

Supplier: Anaspec Inc

Description: This peptide is a C-terminal surface sorting signal with a conserved LPXTG motif, labeled with the Dabcyl/Edans FRET pair. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Surface proteins of Staphylococcus aureus are anchored to the bacterial cell wall by a mechanism requiring this C-terminal sorting signal. Cell wall sorting is the covalent attachment of surface proteins to the peptidoglycan via a C-terminal sorting signal that contains a consensus LPXTG sequence. Cleavage of this FRET substrate by sortase reveals the fluorescent signal that may be measured to study sortase activity. Inhibition of the sortase activity is a potential way of treatment of the staphylococcal infection. The LPXTG motif is conserved in more than 100 surface proteins of Gram-positive pathogens.
Sequence:Dabcyl-QALPETGEE-Edans
MW:1472.6 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103008-418)

Supplier: Anaspec Inc

Description: SN50 is a NF-κB cell-permeable inhibitory peptide. it consists of the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor (K-FGF) attached to a NF-kB p50 nuclear localization sequence (NLS). SN50 inhibits translocation of the NF-kB active complex into the nucleus.
Sequence:AAVALLPAVLLALLAPVQRKRQKLMP
MW:2781.5 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103007-528)

Supplier: Anaspec Inc

Description: The Staphylococcus aureus transpeptidase Sortase A (SrtA) anchors virulence and colonization-associated surface proteins to the cell wall. SrtA selectively recognizes a C-terminal LPXTG motif. SrtA readily reacts with its native substrate Abz-LPETG-Dap(DNP)-NH2, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this FRET substrate can be monitored at Ex/Em=320 nm/420 nm.
Sequence:Abz-LPETG-K(Dnp)-NH2
MW:928 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103007-390)

Supplier: Anaspec Inc

Description: This peptide is amino acids 276 to 286 fragment of the lymphocytic choriomeningitis virus (LCMV) glycoprotein (GP), also known as GP276. It is the H-2Db restricted epitope. LCMV has been routinely exploited for the study of adaptive immune responses to viral infection. Fifty to seventy percent of CD8 T cells at the peak of LCMV infection appear to be specific for five LCMV-derived epitopes including GP276.
Sequence:SGVENPGGYCL
MW:1095.2 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103010-792)

Supplier: Anaspec Inc

Description: 6-HEX is a popular amino-reactive fluorescent probe that is widely used in nucleic acid sequencing and related research. It can also be used to label peptides and oligonucleotides.

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Catalog Number: (102999-378)

Supplier: Anaspec Inc

Description: This sequence corresponds to amino acids 3-13 from murine MBP. MBP induces immune reactivity in multiple sclerosis (MS), a chronic inflammatory demyelinating disease of the CNS. MBP (3-13) is a substrate for Protein Kinase C.
Sequence:QKRPSQRSKYL
MW:1390.6 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103009-940)

Supplier: Anaspec Inc

Description: This peptide is an active segment of LL-37, a peptide derived from the C-terminal domain of human cathelicidin antimicrobial peptide. It has been reported that the LL17-32 peptide exhibits reversal effect on ABCG2-mediated multidrug resistance in cancer cell lines.
Sequence:FKRIVQRIKDFLRNLV
MW:2045.5 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103008-226)

Supplier: Anaspec Inc

Description: This peptide is Histone H3 with amino acid residues 69 to 89 mono-methylated at Lys-79 with an additional C-terminal glycine followed by a biotinylated lysine. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:RLVREIAQDF-K(Me1)-TDLRFQSSAV-K(Biotin)
MW:2848.3 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103006-550)

Supplier: Anaspec Inc

Description: This modified gp100 peptide amino acids 209 to 217 is a MHC-associated HLA-A2.1-restricted epitope derived from melanoma antigen. It can be processed, presented, and recognized by T cells. Alteration of the G209 peptide to G209-2M at the second amino acid changing threonine to a methionine was found to increase the affinity for MHC-associated HLA-A2.1 resulting in enhanced induction of T cells reactive to native gp100
Sequence:IMDQVPFSV
MW:1035.2 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103010-182)

Supplier: Anaspec Inc

Description: The AnaTag™ B-PE Labeling Kit is optimized for use in the conjugation of B-Phycoerythrin (B-PE) to antibodies. B-PE, a fluorescent protein from phycobiliprotein family, has a primary absorption peak at 545 nm with a secondary peak at 563 nm and maximum emission at 578 nm.

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Catalog Number: (103003-254)

Supplier: Anaspec Inc

Description: This is a the tandem repeat sequence of the MUC1 mucin core. MUC1 is a high molecular weight glycoprotein over-expressed by adenocarcinomas, and by different types of bladder tumors. It is also expressed by normal human epithelial cells.
Sequence:APDTRPAPG
MW:1484.6 Da
% peak area by HPLC:95
Storage condition:-20° C

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Supplier: Anaspec Inc

Description: An H-2b-restricted OVA class II epitope.
Sequence: ISQAVHAAHAEINEAGR
MW: 1773.9 Da
% Peak Area by HPLC: ≥ 95%
Storage condition: -20°C

Catalog Number: (103008-430)

Supplier: Anaspec Inc

Description: This peptide sequence is found in residues 25 to 33 of the mouse self/tumor antigen glycoprotein (mgp100). This fragment is a H-2Db–restricted epitope recognized by CD8+ T cells. Mgp100 is an enzyme normally involved in pigment synthesis, and the epitope fragment is typically expressed in both normal melanocytes and melanoma cells.
Sequence:EGSRNQDWL
MW:1104.2 Da
% peak area by HPLC:95
Storage condition:-20° C

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Supplier: Anaspec Inc

Description: This peptide is Histone H3 amino acid residues 1 to 21 acetylated at Lys-9 with a C-terminal GG linker followed by a biotinylated lysine. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:ARTKQTAR-K(Ac)-STGGKAPRKQLA-GGK(Biotin)
MW:2765.3 Da
% peak area by HPLC:95
Storage condition:-20° C