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Catalog Number: (100243-244)
Supplier: Southern Biotechnology
Description: CD11b, the integrin αM subunit, combines with CD18, the integrin β2 subunit, to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1/CD54. Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. Mac-1 expression is rapidly up-regulated on neutrophils after activation and in the same time period that CD62L is shed from the cell surface. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils. Cross-reaction of M1/70 to human CD11b has been observed on monocytes, polymorphonuclear leukocytes, and NK cells.


Catalog Number: (103259-742)
Supplier: Southern Biotechnology
Description: Hamster IgG-Alexa Fluor 488 for use as a control in flow cytometry assays.


Catalog Number: (100245-760)
Supplier: Southern Biotechnology
Description: HRP Anti-Human IgA1 antibody for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.


Catalog Number: (103264-508)
Supplier: Southern Biotechnology
Description: Biotin Anti-Mouse IgG2a antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and multiplex assays.


Catalog Number: (100244-558)
Supplier: Southern Biotechnology
Description: Purified Goat F(ab')2 Anti-Rat IgG antibody with minimal reactivity to mouse proteins for use in ELISA, flow cytometry, and immunohistochemistry assays.


Catalog Number: (100242-038)
Supplier: Southern Biotechnology
Description: Purified Rabbit IgG for use as a control in flow cytometry, immunocytochemistry / immunocytochemistry, western blotting, immunoprecipitation, ChIP, microarray, and in vitro assays and as a standard in ELISA.


Catalog Number: (100242-442)
Supplier: Southern Biotechnology
Description: Biotin Anti-Mouse IL-3 antibody for use in immunohistochemistry / immunocytochemistry, western blotting, ELISA, ELISpot, and multiplex assays.


Catalog Number: (100244-080)
Supplier: Southern Biotechnology
Description: The 695H1-9-9 antibody reacts with a Qa-2-determined alloantigen. It recognizes an epitope distinct from that recognized by monoclonal antibody 1-1-2.


Catalog Number: (101442-608)
Supplier: Southern Biotechnology
Description: Low Endotoxin/Azide Free Anti-Human IL-7 antibody for use in ELISA, immunocytochemistry, and neutralization assays.


Catalog Number: (103264-530)
Supplier: Southern Biotechnology
Description: CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The 145-2C11 monoclonal antibody recognizes an epitope on the 25 kDa ε chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble 145-2C11 can activate primed and naïve T cell in vitro. 145-2C11 can also induce redirected lysis of specific target cells by CTL clones and it can block lysis of specific target cells by antigen-specific CTL’s. Immobilized 145-2C11 can activate both normal T lymphocytes and cloned T cell lines. Under certain conditions, T cell activation by 145-2C11 may result in apoptotic cell death.


Catalog Number: (101442-922)
Supplier: Southern Biotechnology
Description: CD49b, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin α2 chain. CD49b associates noncovalently with CD29, the integrin β1 subunit, to form the heterodimer integrin α2β1 that binds laminin and collagen. It is expressed on B and T lymphocytes, NK cells, monocytes, platelets, fibroblasts, and long-term cultured T cells. CD49b/CD29 mediates the Mg++-dependent adhesion of platelets to collagen. It may also be utilized by fibroblasts for the reorganization of the collagen matrix during wound healing.


Catalog Number: (100245-578)
Supplier: Southern Biotechnology
Description: Chicken Bu-1b, a product of the Bu-1b allele, is expressed on the cell surface as a disulfide-linked homodimer. In 10-week-old H.B15 and H.B2 chickens, Bu-1 is found on 85-90% of bursal cells, 2-8% of thymocytes, 15-27% of spleen cells, and 2-18% of peripheral blood cells. It is also expressed on subsets of macrophages and monocytes but not on granulocytes, erythrocytes, or thrombocytes. In chickens heterozygous for the Bu-1 alleles (Bu-1a/b), Bu-1a does not exhibit allelic exclusion. The monoclonal antibody 5-11G2 reacts with lymphoid cells from CHA and H.B14Ab strains but does not react with cells from H.B14Aa


Catalog Number: (100244-976)
Supplier: Southern Biotechnology
Description: Goat Anti-Equine IgG(H+L)-PE antibody for use in flow cytometry assays.


Catalog Number: (100244-868)
Supplier: Southern Biotechnology
Description: The monoclonal antibody 74-22-15 reacts with > 90% of porcine monocytes and granulocytes and < 5% of peripheral blood lymphocytes.


Catalog Number: (103264-846)
Supplier: Southern Biotechnology
Description: Alexa Fluor 647 Anti-Rat IgG2b antibody for use in flow cytometry, immunohistochemistry, and western blotting assays.


Catalog Number: (100245-520)
Supplier: Southern Biotechnology
Description: FITC Anti-Chicken IgY antibody for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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