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Image Unavailable-103259-954

Anti-CD45.2 Mouse Monoclonal Antibody (Alexa Fluor® 488) [clone: 104]

Catalog Number: (103259-954)
Supplier: Southern Biotechnology
Description: The CD45 antigen is an essential regulator of leukocyte activation and development and is now known to be a protein tyrosine phosphatase, e.g., CD45 is able to dephosporylate the Src family of protein kinases. This activity is known to be required for signal transduction induced by T and B cell antigen receptor engagement, cytokine signaling, and Fc receptor stimulation. The functional state of CD45 also has a pronounced effect on lymphocyte development. CD45 exists in multiple forms, such as the restricted variants (CD45R; see companion products 1660, 1665, 1675, 1685 and 1820) and as allelic forms CD45.1 (Ly-5.1) and CD45.2 (Ly-5.2). The specificity of antibodies to CD45.1 and CD45.2 has been exploited in studies where resolution of donor and recipient cells is essential, such as in gene therapy or bone marrow transplantation. The monoclonal antibody 104 recognizes CD45 (leukocyte common antigen) on all leukocytes of mouse strains expressing the CD45.2 allotype (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129).
Image Unavailable-100244-932

Anti-IgG (H+L) Rabbit Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (100244-932)
Supplier: Southern Biotechnology
Description: Rabbit F(ab')2 Anti-Sheep IgG(H+L)-HRP antibody for use in ELISA and immunohistochemistry assays.
Image Unavailable-100242-628

Anti-ZAP-70 Mouse Monoclonal Antibody (Biotin) [clone: SBZAP]

Supplier: Southern Biotechnology
Description: ZAP-70 is a protein tyrosine kinase (PTK) with the primary role of catalyzing the phosphorylation of tyrosine residues in cellular proteins, and thus, contributes significantly to the initiation of cell signaling. ZAP-70 is normally expressed on T cell and NK cells.

Image Unavailable-103264-584

Anti-CD45R Rat Monoclonal Antibody (Alexa Fluor® 700) [clone: RA3-6B2]

Catalog Number: (103264-584)
Supplier: Southern Biotechnology
Description: CD45R, also known as B220, a member of the protein tyrosine phosphate family and a major cell surface glycoprotein, represents a restricted form of the CD45 family which primarily recognizes only cells of B-lineage from pro-B cell through mature B lymphocytes and prior to the availability of anti-CD19 monoclonal antibodies was commonly used as a pan B-cell marker. It also reacts with certain activated T cells as well as non-MHC-restricted lytically active lymphokine-activated killer (LAK) cells. In vivo administration of RA3-6B2 has been shown to affect differentiation of both T and B cells in normal mice and reduce the level of anti-DNA antibodies and lymphadenopathies in MRL/lpr mice.
Image Unavailable-100244-574

Anti-IgG1 Mouse Antibody [clone: G17E7]

Catalog Number: (100244-574)
Supplier: Southern Biotechnology
Description: Purified Anti-Rat IgG1 antibody for use in flow cytometry, ELISA, and immunohistochemistry assays.
Image Unavailable-100242-526

Anti-IgG (H+L) Goat Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (100242-526)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Mouse IgG(H+L)-HRP antibody with minimal reactivity to human proteins for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.
Image Unavailable-103264-890

Anti-IgG (H+L) Goat Antibody (Alexa Fluor® 647)

Catalog Number: (103264-890)
Supplier: Southern Biotechnology
Description: Goat Anti-Rabbit IgG(H+L)-Alexa Fluor 647 antibody with minimal reactivity to mouse and human proteins for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
Image Unavailable-100244-726

Anti-Rabbit Ig Goat Antibody (bGal (beta Galactosidase))

Catalog Number: (100244-726)
Supplier: Southern Biotechnology
Description: Goat Anti-Rabbit Ig-β-galactosidase antibody with minimal reactivity to human proteins for use in ELISA and immunohistochemistry / immunocytochemistry assays.
Image Unavailable-102971-664

Anti-IgG F(c) Goat Antibody

Catalog Number: (102971-664)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Mouse IgG Fc antibody for use in ELISA and western blotting assays.
Image Unavailable-100244-422

Anti-Ig Goat Antibody (RPE (R-Phycoerythrin))

Supplier: Southern Biotechnology
Description: Goat Anti-Rat Ig-PE antibody with minimal reactivity to mouse proteins for use in flow cytometry assays.

Image Unavailable-100243-764

Anti-TCRbeta Hamster Monoclonal Antibody (Biotin) [clone: H57-597]

Catalog Number: (100243-764)
Supplier: Southern Biotechnology
Description: The αβ TCR is expressed on T lymphocytes of all mouse strains tested. The H57-597 monoclonal antibody does not react with γδ TCR-bearing cells. Plate-bound or soluble H57-597 activates αβ TCR-bearing T cells. In vitro and in vivo, H57-597 can induce immature thymocytes to undergo apoptosis. In vivo administration of H57-597 has been shown to deplete αβ TCR-bearing cells to near completion and prevent graft rejection.
Image Unavailable-101442-520

Mouse IgA Isotype Control [clone: S107] (APC (Allophycocyanin)/Cy7®)

Catalog Number: (101442-520)
Supplier: Southern Biotechnology
Description: Mouse IgA-APC/CY7 for use as a control in flow cytometry assays.
Image Unavailable-MSPP-205304

Anti-IgA Goat Antibody (AP (Alkaline Phosphatase))

Catalog Number: (MSPP-205304)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgA-AP antibody with minimal reactivity to mouse, bovine, and horse serum proteins for use in ELISA assays.
Image Unavailable-100242-072

Rat IgG1 Isotype Control [clone: KLH/G1-2-2] (RPE (R-Phycoerythrin))

Catalog Number: (100242-072)
Supplier: Southern Biotechnology
Description: Rat IgG1-PE for use as a control in flow cytometry assays.
Image Unavailable-100243-326

Anti-CD24 Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: 91]

Catalog Number: (100243-326)
Supplier: Southern Biotechnology
Description: CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P-selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes.
Image Unavailable-100242-194

Human IgG Isotype Control

Catalog Number: (100242-194)
Supplier: Southern Biotechnology
Description: Low Endotoxin/Azide Free Human IgG Fc for use in flow cytometry and in vitro assays and as a standard in ELISA.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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