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Catalog Number: (100242-890)
Supplier: Southern Biotechnology
Description: Biotin Anti-Mouse Kappa antibody for use in ELISA, flow cytometry, immunocytochemistry, and western blotting assays.


Catalog Number: (100246-214)
Supplier: Southern Biotechnology
Description: CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.


Catalog Number: (100246-098)
Supplier: Southern Biotechnology
Description: CD8 is a 33 kDa transmembrane glycoprotein expressed as either a CD8αα homodimer or CD8αβ heterodimer. It is expressed on the “cytotoxic/suppressor” subpopulation of peripheral T cells. CD8 functions primarily as a coreceptor with MHC class I-restricted TCR’s in antigen recognition.

SDS


Catalog Number: (103265-374)
Supplier: Southern Biotechnology
Description: The BC96 monoclonal antibody reacts with human CD25, the 55 kDa interleukin-2 receptor α chain (IL-2Rα). CD25 is expressed by early progenitors of T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor β chain) and CD132 (common γ chain) to form the high affinity IL-2 receptor. CD25 plays a role in lymphocyte differentiating and activation/proliferation. CD25 is expressed on activated B cells, monocytes/macrophages, and T cells.


Catalog Number: (100243-132)
Supplier: Southern Biotechnology
Description: CD4 is a type I transmembrane glycoprotein expressed on most thymocytes and the helper/inducer subpopulation of mature T lymphocytes of all mouse strains tested. CD4 has also been detected at low density on pluripotent hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic lymphoid precursors. The CD4 antigen functions as a co-receptor, interacting with class II major histocompatability complex (MHC) molecules in the recognition of foreign antigens by T cells. In vivo and in vitro treatment with the GK1.5 monoclonal antibody effectively depletes CD4+ cells. GK1.5 also blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.


Supplier: Southern Biotechnology
Description: CD9 is a 24 kDa member of the transmembrane 4 superfamily (TM4-SF) of cell surface receptors. It is expressed strongly on platelets, lymphoid progenitor cells, activated lymphocytes and endothelia, and, weakly, on eosinophils, granulocytes, monocytes, and macrophages. CD9 functions as an adhesion molecule where it mediates platelet aggregation and activation.

Catalog Number: (103259-802)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG2b-Alexa Fluor 647 antibody with minimal reactivity to human proteins for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100243-472)
Supplier: Southern Biotechnology
Description: Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCRαβ+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B and T cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.


Catalog Number: (100242-322)
Supplier: Southern Biotechnology
Description: Goat F(ab’)2 Anti-Mouse Ig-AP antibody with minimal reactivity to human proteins for use in ELISA, immunocytochemistry, western blotting, and ELISpot assays.


Catalog Number: (100245-044)
Supplier: Southern Biotechnology
Description: Goat Anti-Guinea Pig IgG(H+L)-AP antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (103264-468)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgE-FITC antibody for use in flow cytometry, immunocytochemistry, and western blotting assays.


Catalog Number: (100242-120)
Supplier: Southern Biotechnology
Description: Rat IgM-FITC for use as a control in flow cytometry and immunohistochemistry assays.


Catalog Number: (100244-398)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Human Lambda-FITC antibody with minimal reactivity to mouse proteins for use in flow cytometry assays.


Catalog Number: (103259-832)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG3-Alexa Fluor 555 antibody with minimal reactivity to human proteins for use in immunohistochemistry / immunocytochemistry and western blotting assays.


Catalog Number: (101442-752)
Supplier: Southern Biotechnology
Description: CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P-selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes.


Catalog Number: (103260-082)
Supplier: Southern Biotechnology
Description: Purified Anti-Monkey IgG for use in ELISA, flow cytometry, and western blotting assays.


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