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Catalog Number: (103265-220)
Supplier: Southern Biotechnology
Description: Alexa Fluor 488 Anti-Human IgG4 Fc antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (103265-450)
Supplier: Southern Biotechnology
Description: CD158e1 is a 70 kDa transmembrane glycoprotein and a killer cell immunoglobulin (Ig)-like receptor (KIR) that is expressed on a subset of natural killer cells and T cells. The monoclonal antibody DX9 is expressed on a subset of CD3-, CD56+ NK cells isolated from peripheral blood at varying levels (<0.1% to 61%) among individuals but not on thymocytes, B lymphocytes, granulocytes, or monocytes. Interactions with CD158e1 and certain MHC HLA-B antigens on a target cell inhibits cytotoxicity, possibly preventing target cell lysis and death. KIR and MHC class I interactions may regulate NK and T cell response to antigen stimulation.


Catalog Number: (100244-218)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgM-HRP antibody for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.


Catalog Number: (100244-610)
Supplier: Southern Biotechnology
Description: PE Anti-Rat IgG2b antibody for use in flow cytometry assays.


Catalog Number: (103264-192)
Supplier: Southern Biotechnology
Description: Low Endotoxin/Azide Free Rabbit IgG for use as a control in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, ChIP, microarray, and in vivo / in vitro assays and as a standard in ELISA.


Catalog Number: (103260-014)
Supplier: Southern Biotechnology
Description: Goat Anti-Human Lambda-Alexa Fluor 647 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (101442-742)
Supplier: Southern Biotechnology
Description: CD11b (integrin αM subunit) combines with CD18 (integrin β2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.


Catalog Number: (103265-046)
Supplier: Southern Biotechnology
Description: Donkey F(ab')2 Anti-Mouse IgG(H+L)-HRP antibody for use in ELISA assays.


Catalog Number: (103260-210)
Supplier: Southern Biotechnology
Description: CD45RA is a 220 kDa exon A-dependent isoform of CD45. It is expressed on 40-50% of CD4+ peripheral T cells, 50% of peripheral CD8+ T cells, and a portion of B lymphocytes and monocytes.


Catalog Number: (103259-870)
Supplier: Southern Biotechnology
Description: HRP Anti-Mouse IgG3 antibody for use in ELISA assays.


Catalog Number: (100245-016)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Hamster IgG(H+L)-FITC antibody with minimal reactivity to mouse and rat proteins for use in flow cytometry and immunohistochemistry assays.


Catalog Number: (103265-044)
Supplier: Southern Biotechnology
Description: Donkey F(ab')2 Anti-Mouse IgG(H+L)-FITC antibody for use in fluorescent assays.


Catalog Number: (101190-282)
Supplier: Southern Biotechnology
Description: Protein tyrosine residues are phosphorylated as a result of intracellular protein kinase activation (e.g., via growth factors) during normal growth and development and in oncogenesis. The most abundant population of target proteins for tyrosine phosphorylation is cell surface glycoproteins. Antibodies to phosphotyrosine enable the detection, isolation, and characterization of proteins containing phosphotyrosine. The monoclonal antibody PY20 prevents internalization of activated receptors (e.g., EGFR) when microinjected into cells. The affinity of PY20 for phosphotyrosine is approximately 10-6 to 10-7 M. PY20 binding to phosphorylated tyrosines can be inhibited by free phosphotyrosine and phenylphosphate but not by phosphoserine, phosphothreonine, or free phosphate.


Catalog Number: (100244-106)
Supplier: Southern Biotechnology
Description: The monoclonal antibody 34-5-8S reacts with a conformational epitope on H-2Dd MHC Class I found on the N-terminal domains of α1 and α2 chains when complexed with β2-microglobulin. The antibody does not react with H-2Dd α chains synthesized in vitro. Weak cross-reactivity with cells from mice of the H-2b, H-2q, and H-2s haplotypes has been observed by flow cytometric analysis. Reactivity with cells from mice of the H-2f, H-2k, H-2p, and H-2r haplotypes has not been observed. 34-5-8S has been reported to block the recognition of H-2Dd by Ly-49A+, Ly-49C+, and Ly-49G2+ natural killer cells.


Catalog Number: (103265-148)
Supplier: Southern Biotechnology
Description: CD3 is a member of the T cell receptor-associated CD3 complex. The monoclonal antibody CT-3 recognizes a complex of at least three polypeptides of Mr 20, 19, and 17 kDa (two of which are N-glycosylated) on chicken T cells. The antibody also coprecipitates a polypeptide of 90 kDa from digitonin solubilized T cell lysates, which can be reduced to two polypeptides of Mr 50 and 40 kDa.


Catalog Number: (103265-034)
Supplier: Southern Biotechnology
Description: Donkey Anti-Mouse IgG(H+L)-Biotin antibody for use in ELISA assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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