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Description: Purified Rat IgM for use as a control in flow cytometry and immunohistochemistry assays and as a standard in ELISA.
Catalog Number: 100242-118
Supplier: Southern Biotechnology


Description: Biotin Anti-Human IL-5 antibody for use in flow cytometry, ELISA, and immunohistochemistry / immunocytochemistry assays.
Catalog Number: 100242-314
Supplier: Southern Biotechnology


Description: Goat Anti-Mouse IgG1-HRP antibody for use in ELISA and immunocytochemistry assays.
Catalog Number: 103265-598
Supplier: Southern Biotechnology


Description: CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow.
Catalog Number: 100243-284
Supplier: Southern Biotechnology


Description: Goat Anti-Mouse IgG(H+L)-HRP antibody for use in ELISA assays.
Catalog Number: 103264-408
Supplier: Southern Biotechnology


Description: Goat Anti-Hamster IgG(H+L)-FITC antibody for use in western blotting and other fluorescent assays.
Catalog Number: 100244-990
Supplier: Southern Biotechnology


Description: AP Anti-Mouse IgG2b antibody for use in ELISA,, immunocytochemistry, and western blotting assays.
Catalog Number: 103259-854
Supplier: Southern Biotechnology


Description: Purified Anti-Mouse IgG3 antibody for use in ELISA and flow cytometry assays.
Catalog Number: 103259-864
Supplier: Southern Biotechnology


Description: The monoclonal antibody 34-5-8S reacts with a conformational epitope on H-2Dd MHC Class I found on the N-terminal domains of α1 and α2 chains when complexed with β2-microglobulin. The antibody does not react with H-2Dd α chains synthesized in vitro. Weak cross-reactivity with cells from mice of the H-2b, H-2q, and H-2s haplotypes has been observed by flow cytometric analysis. Reactivity with cells from mice of the H-2f, H-2k, H-2p, and H-2r haplotypes has not been observed. 34-5-8S has been reported to block the recognition of H-2Dd by Ly-49A+, Ly-49C+, and Ly-49G2+ natural killer cells.
Catalog Number: 100244-108
Supplier: Southern Biotechnology


Description: CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor crosslinking with peak expression occurring between 48 and 72 hours post-activation. The interaction of CD80 with its ligands, CD28 and CD152 (CTLA-4), provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex. The monoclonal antibody 1G10 blocks binding of CTLA-4 to CD80 but it does not block stimulation of T cells by natural antigen-presenting cells.
Catalog Number: 100243-646
Supplier: Southern Biotechnology


Description: Purified Goat Anti-Rabbit IgG Fab antibody with minimal reactivity to mouse and human serum proteins for use in ELISA assays.
Catalog Number: 103264-910
Supplier: Southern Biotechnology


Description: Goat F(ab’)2 IgG-APC for use as a control in flow cytometry assays.
Catalog Number: 100242-034
Supplier: Southern Biotechnology


Description: Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR) and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCRαβ+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B and T cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.
Catalog Number: 100243-452
Supplier: Southern Biotechnology


Description: CD62E represents the 97 kDa type I transmembrane glycoprotein E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1). It is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial attachment and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues. CD62P is a 140 kDa membrane glycoprotein formerly known as platelet activation-dependent granule membrane protein (PADGEM) or GMP-140. It is expressed on platelets, megakaryocytes, and epithelium. It is thought to mediate the adhesive interactions of neutrophils and monocytes with endothelium in inflammatory responses and of activated platelets to neutrophils and monocytes in hemostasis. The monoclonal antibody 1.2B6 recognizes a common epitope shared by CD62E and CD62P.
Catalog Number: 100246-006
Supplier: Southern Biotechnology


Description: FITC Anti-Human IgE antibody for use in western blotting assays.
Catalog Number: 103265-686
Supplier: Southern Biotechnology


Description: HRP Anti-Hamster IgG3 antibody for use in ELISA assays.
Catalog Number: 103264-676
Supplier: Southern Biotechnology


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