Supplier: Anaspec Inc

Description: This biotinylated Aß(1-42) contains an 6-carbon long chain (LC) to provide more accessibility for avidin attachment.
Sequence: Biotin-LC-DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
MW: 4853.6 Da
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

Supplier: Anaspec Inc

Description: This peptide is Histone H3 amino acid residues 1 to 21 mono-methylated at Lys-9 with a C-terminal GG linker followed by a biotinylated lysine. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:ARTKQTAR-K(Me1)-STGGKAPRKQLA-GGK(Biotin)
MW:2737.2 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: (103007-586)

Supplier: Anaspec Inc

Description: This peptide is an enterokinase substrate. Enterokinase, also known as enteropeptidase, is a membrane-bound serine endopeptidase that initiates the activation of pancreatic hydrolases by cleaving and activation of trypsinogen. Enteropeptidase is present in the duodenum. Proendopeptidase may be also detected after activation with trypsin and cleavage of this substrate.
Sequence:GDDDDK-βNA
MW:788.8 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103010-208)

Supplier: Anaspec Inc

Description: Oxonol VI is used as an optical indicator for membrane potentials in lipid vesicles. Oxonol VI is a sensitive slow-response membrane potential probe whose magnitude of optical response is much larger than that of faster response probes (Oxonol V). The fluorescence of Oxonol VI decreases upon membrane hyperpolarization. In general, slow response probes are suitable for detecting changes in average membrane potentials of nonexcitable cells caused by respiratory activity, ion-channel permeability, drug binding and other factors.

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Supplier: Anaspec Inc

Description: This peptide is Histone H3 amino acid residues 1 to 21 di-methylated at Lys-4 with a C-terminal GG linker followed by a biotinylated lysine. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:ART-K(Me2)-QTARKSTGGKAPRKQLA-GGK(Biotin)
MW:2751.2 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

Description: This peptide is a neurotoxin that blocks N-type calcium channels.
Sequence:CKS(Hyp)GSSCS(Hyp)TSYNCCRSCN(Hyp)YTKRCY-NH2
MW:3037.4 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

Description: This is cysteine-modified N-terminus of Beta-Amyloid (1-42).
Cysteine modification of beta-amyloid peptides enables specific immobilization via maleimide-terminated surface at the N-terminal cysteine to the mica surface usually used in AFM interaction studies. Since the N-terminal is not involved in fibril formation, certain studies have adopted this strategy of immobilizing the peptide using the maleimide-cystein linkage/functionalization and study Beta-Amyloid interactions.
Sequence: CDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Molecular Weight: 4617.3 Da
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

Catalog Number: (102996-878)

Supplier: Anaspec Inc

Description: The native peptide AAKIQASFRGHMARKK (27173) is a synthetic PKC substrate derived from the sequence of neurogranin, a naturally occurring PKC substrate. The peptide is proven to be a PKC substrate with quite good specificity. It is phosphorylated by purified PKC with a Km of 150 nM. No significant phosphorylation of the peptide by either PKA or by CaMK 2 is reported. Substituting Arg36 with Ile causes a significant reduction in the affinity for PKC. Replacing Lys30 with Arg enhances the catalytic efficiency (Vmax/Km) for PKC but diminishes the selectivity of the substrate for PKC. It is generally considered that basic amino acids on both sides of the phosphorylated Ser are important structural determinants in PKC substrates. In addition, the presence of particular basic amino acids (Arg vs Lys) may also contribute to the degree of selectivity of a substrate for PKC.
Sequence:Biotin-LC-AAKIQASFRGHMARKK
MW:2139.6 Da
% peak area by HPLC:95
Storage condition:-20° C

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Supplier: Anaspec Inc

Description: Aß (1-40) together with Aß (1-42) are two major C-terminal variants of the Aß protein constituting the majority of Aßs. These undergo post-secretory aggregation and deposition in the Alzheimer’s disease brain.
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
Molecular Weight: 4329.9 Da
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

Catalog Number: (103008-380)

Supplier: Anaspec Inc

Description: This is amino acids 180-199 fragment of myelin proteolipid protein (PLP). PLP, the most abundant myelin protein of the central nervous system, has been used in multiple sclerosis (MS) studies. MS is a chronic inflammatory demyelinating disease of the CNS,
Sequence: WTTCQSIAFPSKTSASIGSL
MW: 2085.4 Da
% Peak area by HPLC: 95
Storage condition: -20°C

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Catalog Number: (103006-064)

Supplier: Anaspec Inc

Description: This is a fluorescent 5-FAM labeled scrambled Beta-Amyloid peptide, Abs/Em=494/521 nm.
Sequence: 5-FAM-AIAEGDSHVLKEGAYMEIFDVQGHVFGGKIFRVVDLGSHNVA
MW: 4873.4
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

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Catalog Number: (103011-400)

Supplier: Anaspec Inc

Description: Calcein, AM is a cell-permeant and non-fluorescent compound that is widely used for determining cell viability

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Catalog Number: (103003-366)

Supplier: Anaspec Inc

Description: Defensins are small cysteine-rich cationic proteins found in both vertebrates and invertebrates. They have host defense properties, and are active against bacteria, fungi and many viruses. Beta-defensins are the most widely distributed, being secreted by leukocytes and epithelial cells of many kinds
Sequence:GIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK (Disulfide bridge: 11-40, 18-33, 23-41)
MW:5155.2 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103007-214)

Supplier: Anaspec Inc

Description: This is amino acids 1 to 40 fragment of the beta-amyloid peptide with lysine substituted for glutamic acid at position 22, found in Italian families. The Italian mutation of beta-amyloid 1-40 (E22K) aggregates more rapidly and with more potent neurotoxicity than wild-type beta-amyloid 1-40. The formation of a salt bridge between Lys-22 and Asp-23 in the minor conformer might be a reason why E22K-beta-amyloid 40 is more pathogenic than wild-type beta-amyloid 40.
Sequence: DAEFRHDSGYEVHHQKLVFFAKDVGSNKGAIIGLMVGGVV
Molecular Weight: 4328.9 Da
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

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Catalog Number: (103007-236)

Supplier: Anaspec Inc

Description: This pro-apoptotic peptide, composed of D-amino acids, is a alpha-helical amphipathic peptide toxic to eukaryotic cells if internalized by a suitable targeting mechanism. It disrupts mitochondrial membranes upon receptor-mediated cell internalization and causes programmed cell death.
Sequence:klaklakklaklak-NH2
MW:1523 Da
% peak area by HPLC:95
Storage condition:-20° C

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Catalog Number: (103007-584)

Supplier: Anaspec Inc

Description: This is amino acids 1 to 12 fragment of the beta-amyloid peptide. This N-terminal sequence was used to develop the antibody BR88. An antiserum directed against this peptide stained numerous tangle-bearing cells and bodies, as well as the neuritic component of plaques and neuropil threads. It stained a large number of pyramid cells.
Sequence: DAEFRHDSGYEV
Molecular Weight: 1424.5 Da
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

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