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Catalog Number: (100243-620)
Supplier: Southern Biotechnology
Description: CD69, also known as very early activation (VEA) antigen, is a disulfide-linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa. It is a C-type lectin most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. CD69 is widely expressed on hematopoietic cells, including lymphocytes, neutrophils and eosinophils. Although not detectable on resting lymphocytes, its expression is rapidly upregulated upon activation of T, B and NK cells, and neutrophils. Constitutive expression of CD69 on subsets of thymocytes suggests that it may be involved in regulation of developmental events in addition to its role in activation of a variety of hematopoietic cells. The monoclonal antibody H1.2F3 augments PMA-induced T-cell proliferation and induces redirected lysis of Fc receptor-bearing target cells by NK cells.


Catalog Number: (100244-942)
Supplier: Southern Biotechnology
Description: Purified Rabbit F(ab')2 Anti-Goat IgG(H+L) antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (103265-238)
Supplier: Southern Biotechnology
Description: HRP Anti-Human Kappa antibody for use in ELISA assays.


Catalog Number: (100244-450)
Supplier: Southern Biotechnology
Description: Goat Anti-Rat IgM-Biotin antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (103259-782)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Mouse IgG2a antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (103265-308)
Supplier: Southern Biotechnology
Description: CD11c is a 150 kDa adhesion glycoprotein that associates with β2 integrin to form the CD11c/CD18 heterodimer that binds CD54 (ICAM-1) and fibrinogen. It is expressed on NK cells, a subset of B and T cells, granulocytes, monocytes, and macrophages. It functions in cytotoxic T cell killing and in neutrophil and monocyte adhesion to endothelium.


Catalog Number: (100246-310)
Supplier: Southern Biotechnology
Description: CD51 represents the integrin αV chain that associates with integrin β3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils, and platelets. CD51 is the most promiscuous integrin α subunit as it can form heterodimers with the β1 (CD29), β3 (CD61), β5, β6 and β8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.


Catalog Number: (100245-120)
Supplier: Southern Biotechnology
Description: Rabbit Anti-Sheep IgG(H+L)-FITC antibody for use in immunohistochemistry / immunocytochemistry and western blotting assays.


Catalog Number: (103264-886)
Supplier: Southern Biotechnology
Description: Goat Anti-Rabbit IgG(H+L)-HRP antibody with minimal reactivity to mouse, rat, and human proteins for use in ELISA assays.


Catalog Number: (103264-596)
Supplier: Southern Biotechnology
Description: CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes, and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN γ, IL-1, TNF-α, lipopolysaccharide, and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1.


Catalog Number: (101442-674)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG3-APC/CY7 antibody with minimal reactivity to human proteins for use in flow cytometry assays.


Catalog Number: (103265-684)
Supplier: Southern Biotechnology
Description: The monoclonal antibody KUL01 is useful in the study of the development, distribution, function, and ontogeny of the mononuclear phagocyte system (MPS) of the chicken by exclusively recognizing the cells of the MPS. It identifies chicken monocytes and macrophages as well as interdigitating cells and activated microglia cells. This antibody does not react with B (Bu-1+) or T (CD3+) lymphocytes.


Catalog Number: (100244-600)
Supplier: Southern Biotechnology
Description: Biotin Anti-Rat IgG2a antibody for use in flow cytometry, ELISA, immunohistochemistry, and ELISpot assays.


Catalog Number: (100244-842)
Supplier: Southern Biotechnology
Description: Porcine CD4 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. CD4 is an accessory molecule in the recognition of foreign antigens in association with MHC Class II molecules by T lymphocytes.


Catalog Number: (100245-812)
Supplier: Southern Biotechnology
Description: AP Anti-Human IgG4 Fc antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (101442-776)
Supplier: Southern Biotechnology
Description: CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B-cell specific stimuli with peak expression at 18-42 hours after stimulation. CD86, along with CD80 (B7-1), is an important accessory molecule in T cell costimulation via its interaction with CD28 and CD152 (CTLA-4). Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. The monoclonal antibody GL1 blocks mixed lymphocyte reactions and stimulation of T cells by antigen-presenting cells.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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