You Searched For: OPTEM

Catalog Number: (100245-048)

Supplier: Southern Biotechnology

Description: Purified Goat Anti-Chicken IgY(H+L) antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.

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Catalog Number: (100242-724)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG2b-CY5 antibody with minimal reactivity to human proteins for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.

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Catalog Number: (100242-032)

Supplier: Southern Biotechnology

Description: Goat F(ab’)2 IgG-PE for use as a control in flow cytometry assays.

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Catalog Number: (100246-446)

Supplier: Southern Biotechnology

Description: CD74 represents a type II integral membrane protein known as MHC class II-associated invariant chain. It is moderately expressed on B cells and weakly on monocytes and macrophages. CD74 is also found on a subset of activated T cells, Langerhans cells, dendritic cells, and some epithelial cells. CD74 may play a role in antigen processing and presentation through intracellular transport and expression of class II molecules on the cell surface.

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Catalog Number: (100244-838)

Supplier: Southern Biotechnology

Description: Porcine CD3ε is a member of the T-cell receptor-associated CD3 complex. It is found on a subpopulation of thymocytes and on all pig T lymphocytes.

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Catalog Number: (100245-716)

Supplier: Southern Biotechnology

Description: HRP Anti-Human IgG1 Hinge antibody for use in ELISA, immunohistochemistry, and western blotting assays.

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Catalog Number: (103259-724)

Supplier: Southern Biotechnology

Description: Rat IgG2c-PE for use as a control in flow cytometry assays.

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Catalog Number: (103259-980)

Supplier: Southern Biotechnology

Description: The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid production of primitive hematopoietic progenitor cells. A variety of cytokines act synergistically with SCF to stimulate proliferation and differentiation of bone marrow progenitor cells. For example, SCF plus IL-7 can stimulate the combined myeloid and B cell differentiation of uncommitted hematopoietic progenitor cells. SCF/c-Kit also participates in erythropoiesis in both the bone marrow and spleen. Loss-of-function mutations for SCF/c-Kit lead to a variety of pleiotropic developmental defects while gain-of-function mutations can lead to constitutive activation of the kit receptor and links to cancer. Examples of the former are mast cell deficiency and severe macrocytic anemia while the latter mutation has been identified in mastocytomas.

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Supplier: Southern Biotechnology

Description: PE Anti-Mouse Kappa antibody for use in flow cytometry assays.

Catalog Number: (100246-058)

Supplier: Southern Biotechnology

Description: CD4 is a 55 kDa type I transmembrane glycoprotein and a member of the Ig-SF of cell surface receptors. It is expressed predominantly on the “helper/inducer” subpopulation of mature T lymphocytes and on monocytes and macrophages. Domains 1 and 2 bind to MHC Class II antigens, while domains 3 and 4 may be involved in cis interactions with the CD3/TCR complex. CD4 functions as an accessory molecule in the recognition of foreign antigens in association with MHC class II antigens by T cells.

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Catalog Number: (103264-976)

Supplier: Southern Biotechnology

Description: Rabbit Anti-Sheep IgG(H+L)-FITC antibody with minimal reactivity to human serum proteins for use in immunohistochemistry and western blotting assays.

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Catalog Number: (103264-616)

Supplier: Southern Biotechnology

Description: Ly-6C is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T-cell subsets. Mice with the Ly-6.2 allotype (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have subsets of CD4+Ly-6C+ and CD8+Ly-6C+ cells while Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+Ly-6C+ lymphocytes. Ly-6C may play a role in the development and maturation of lymphocytes.

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Catalog Number: (100243-542)

Supplier: Southern Biotechnology

Description: CD45R, also known as B220, a member of the protein tyrosine phosphate family and a major cell surface glycoprotein, represents a restricted form of the CD45 family which primarily recognizes only cells of B-lineage from pro-B cell through mature B lymphocytes and prior to the availability of anti-CD19 monoclonal antibodies was commonly used as a pan B-cell marker. It also reacts with certain activated T cells as well as non-MHC-restricted lytically active lymphokine-activated killer (LAK) cells. In vivo administration of RA3-6B2 has been shown to affect differentiation of both T and B cells in normal mice and reduce the level of anti-DNA antibodies and lymphadenopathies in MRL/lpr mice.

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Catalog Number: (100242-764)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgE-HRP antibody for use in ELISA, immunocytochemistry, and western blotting assays.

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Catalog Number: (100244-396)

Supplier: Southern Biotechnology

Description: Purified Goat F(ab')2 Anti-Human Lambda antibody with minimal reactivity to mouse proteins for use in ELISA, flow cytometry, and stimulation assays.

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Catalog Number: (101442-980)

Supplier: Southern Biotechnology

Description: CD45, also known as the leukocyte common antigen (LCA), exists as four different isoforms (180, 190, 205, 220 kDa) that are generated by alternative splicing of three exons. LCA is found on all cells of hematopoietic origin, except erythrocytes and platelets. CD45 expression is required for T cell and B cell antigen receptor-mediated activation.

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