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Description: CD11b, the integrin αM subunit, combines with CD18, the integrin β2 subunit, to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1/CD54. Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. Mac-1 expression is rapidly up-regulated on neutrophils after activation and in the same time period that CD62L is shed from the cell surface. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils. Cross-reaction of M1/70 to human CD11b has been observed on monocytes, polymorphonuclear leukocytes, and NK cells.
Catalog Number: 100243-238
Supplier: Southern Biotechnology


Description: Rabbit F(ab’)2 IgG-FITC for use as a control in flow cytometry assays.
Catalog Number: 100242-046
Supplier: Southern Biotechnology


Description: The monoclonal antibody 15-5-5 reacts with the H-2Dk class I alloantigen. It cross-reacts with H-2Kd and with cells from mice with the H-2f haplotype. The antibody does not react with other (e.g., a, b, p, q, r, s) haplotypes.
Catalog Number: 100244-124
Supplier: Southern Biotechnology


Description: Low Endotoxin/Azide Free Anti-Human IL-7 antibody for use in ELISA, immunocytochemistry, and neutralization assays.
Catalog Number: 101442-608
Supplier: Southern Biotechnology


Description: The 3C4 monoclonal antibody reacts with the cell surface glycoprotein mouse CD102 (ICAM-2), a ligand for the leucocyte integrin CD11a/CD18 (LFA-1). CD102 is constitutively expressed on T cells, B cells, and at high levels on vascular endothelial cells. It is also expressed on a variety of leukocyte cell lines. The 3C4 antibody blocks the interaction between ICAM-2 and LFA-1.
Catalog Number: 103264-672
Supplier: Southern Biotechnology


Description: CD45, also known as the leukocyte common antigen (LCA), exists as four different isoforms (180, 190, 205, 220 kDa) that are generated by alternative splicing of three exons. LCA is found on all cells of hematopoietic origin, except erythrocytes and platelets. CD45 expression is required for T cell and B cell antigen receptor-mediated activation.
Catalog Number: 103265-394
Supplier: Southern Biotechnology


Description: Purified Goat Anti-Rat IgG(H+L) antibody with minimal reactivity to mouse serum proteins for use in ELISA assays.
Catalog Number: 103264-828
Supplier: Southern Biotechnology


Description: CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The 145-2C11 monoclonal antibody recognizes an epitope on the 25 kDa ε chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble 145-2C11 can activate primed and naïve T cell in vitro. 145-2C11 can also induce redirected lysis of specific target cells by CTL clones and it can block lysis of specific target cells by antigen-specific CTL’s. Immobilized 145-2C11 can activate both normal T lymphocytes and cloned T cell lines. Under certain conditions, T cell activation by 145-2C11 may result in apoptotic cell death.
Catalog Number: 103264-530
Supplier: Southern Biotechnology


Description: HRP Anti-Human IgA1 antibody for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.
Catalog Number: 100245-760
Supplier: Southern Biotechnology


Description: Hamster IgG-Alexa Fluor 488 for use as a control in flow cytometry assays.
Catalog Number: 103259-742
Supplier: Southern Biotechnology


Description: Biotin Anti-Mouse IgG2a antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and multiplex assays.
Catalog Number: 103264-508
Supplier: Southern Biotechnology


Description: Goat Anti-Equine IgG(H+L)-PE antibody for use in flow cytometry assays.
Catalog Number: 100244-976
Supplier: Southern Biotechnology


Description: CD79 is a disulfide-linked heterodimer composed of an α chain (CD79a) and a β chain (CD79b) that associates non-covalently with membrane immunoglobulin to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes first appearing on the surface at the pro-B cell stage and remaining through all stages of B cell differentiation prior to plasma cells. Crosslinking of the BCR leads to B cell activation. The monoclonal antibody CB3-1 reacts with the β chain of CD79.
Catalog Number: 100246-380
Supplier: Southern Biotechnology


Description: Purified Goat Anti-Human IgG(H+L) antibody for use in ELISA assays.
Catalog Number: 103264-722
Supplier: Southern Biotechnology


Description: Chicken Bu-1b, a product of the Bu-1b allele, is expressed on the cell surface as a disulfide-linked homodimer. In 10-week-old H.B15 and H.B2 chickens, Bu-1 is found on 85-90% of bursal cells, 2-8% of thymocytes, 15-27% of spleen cells, and 2-18% of peripheral blood cells. It is also expressed on subsets of macrophages and monocytes but not on granulocytes, erythrocytes, or thrombocytes. In chickens heterozygous for the Bu-1 alleles (Bu-1a/b), Bu-1a does not exhibit allelic exclusion. The monoclonal antibody 5-11G2 reacts with lymphoid cells from CHA and H.B14Ab strains but does not react with cells from H.B14Aa
Catalog Number: 100245-578
Supplier: Southern Biotechnology


Description: The 695H1-9-9 antibody reacts with a Qa-2-determined alloantigen. It recognizes an epitope distinct from that recognized by monoclonal antibody 1-1-2.
Catalog Number: 100244-080
Supplier: Southern Biotechnology


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