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Catalog Number: (100242-262)
Supplier: Southern Biotechnology
Description: Purified Anti-Human IL-10 antibody for use in flow cytometry, immunohistochemistry, ELISA, ELISpot, western blotting, and multiplex assays.


Catalog Number: (100242-168)
Supplier: Southern Biotechnology
Description: Purified Human IgG1 Kappa for use as a control in flow cytometry, immunoprecipitation, Fc mediated stimulation, blocking, and in vitro assays, as a standard in ELISA, and for immobilization in surface plasmon resonance.


Catalog Number: (103265-270)
Supplier: Southern Biotechnology
Description: CD56, an isoform of the neural cell adhesion molecule (NCAM), is a heavily glycosylated type I transmembrane protein. On human hematopoietic cells its expression is restricted to NK cells and a subpopulation of T lymphocytes (known as large granular lymphocytes) which demonstrate natural killer activity. While it is clear that NCAM plays a role in homotypic adhesion of neuronal cells, the significance of CD56 expression on NK cells is not clear and remains controversial.


Catalog Number: (100244-338)
Supplier: Southern Biotechnology
Description: Goat Anti-Human Kappa-TRITC antibody for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.


Catalog Number: (100246-040)
Supplier: Southern Biotechnology
Description: CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3 is expressed on 70-80% of normal peripheral blood lymphocytes and on 10-20% of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation. The monoclonal antibody UCHT1 reacts with the 20 kDa ε chain of the CD3/TCR complex.


Supplier: Southern Biotechnology
Description: CD44, also known as phagocytic glycoprotein-1 (Pgp-1), exists as a large number of different isoforms resulting from alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type I transmembrane protein. Other variable isoforms containing glycosaminoglycans have molecular weights ranging from 110 to 250 kDa and are widely expressed on hematopoietic and non-hematopoietic cells. CD44 contributes to the adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. It also plays a functional role in cell migration, lymphocyte homing, and adhesion during hematopoiesis and lymphocyte activation.

Supplier: Southern Biotechnology
Description: FITC Anti-Mouse Kappa antibody for use in flow cytometry, immunohistochemistry, and western blotting assays.

Catalog Number: (100245-794)
Supplier: Southern Biotechnology
Description: Biotin Anti-Human Lambda antibody for use in ELISA, flow cytometry, western blotting, and immunoprecipitation assays.


Catalog Number: (100243-444)
Supplier: Southern Biotechnology
Description: The lymphocyte Fcγ receptors recognize the Fc portion of IgG, presented either as immune complexes or as free antibody. The different classes of receptors are distinct because of varying size, tissue distribution and affinity for IgGs. The Fc type II receptor is expressed on a wide variety of cells including B cells, hematopoietic cells, monocyte/macrophages, neutrophils, platelets, Langerhans cells, eosinophils, basophils, trophoblasts, and endothelial cells of the placenta. The Fcγ type III receptors are higher affinity than the type II and are expressed on macrophages, NK cells and neutrophils. Both types of receptors can be expressed on the same cell and in varying ratios. The receptors are constitutively expressed, although cytokines and lymphokines can modulate their expression. Besides identifying FcγR+ cells, monoclonal antibodies to the FcγII/III receptor have been used to block Fc receptor binding of IgG, Fc-mediated signal transduction and effector functions, clearance of immune complexes and to attenuate infection by organisms dependent on FcγR for parasitic invasion. The monoclonal antibody 93 recognizes a conformational epitope formed by FcγII and FcγIII receptors.


Catalog Number: (103259-794)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG2a-AP antibody with minimal reactivity to human, bovine, and horse serum proteins for use in ELISA assays.


Catalog Number: (100242-444)
Supplier: Southern Biotechnology
Description: Purified Anti-Mouse IL-17A antibody for use in flow cytometry, ELISA, and ELISpot assays.


Catalog Number: (101190-240)
Supplier: Southern Biotechnology
Description: Low Endotoxin/Azide Free Anti-Mouse GM-CSF antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, ELISA, ELISpot, multiplex, and neutralization assays.


Catalog Number: (103264-546)
Supplier: Southern Biotechnology
Description: CD5, also known as Lyt-1, is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B-cell antigen CD72. The frequency of CD5+ B cells exhibits strain-dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells. Binding of CD5 on the T cell surface can augment alloantigen- or mitogen-induced lymphocyte proliferation and induces increased cytosolic free calcium, IL-2 secretion, and IL-2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T-cell and B-cell receptors.


Catalog Number: (100246-158)
Supplier: Southern Biotechnology
Description: CD14 is a 55 kDa glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells, and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.


Catalog Number: (103264-606)
Supplier: Southern Biotechnology
Description: Ly-6A/E, also known as Sca-1, is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly-6.1 and Ly-6.2 allotypes. In the periphery, Ly-6A/E exhibits a pattern of expression which is based on differences between the two allotypes. Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Ly-6A/E+ resting peripheral lymphocytes whereas Ly-6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have relatively high numbers of Ly-6A/E+ lymphocytes. The expression of Ly-6A/E is dramatically upregulated in all strains upon cellular activation. Studies with the monoclonal antibody D7 suggest that Ly-6A/E may be involved in B and T lymphocyte responses and it appears that the antigen may be required for T-cell receptor-mediated T-cell activation.


Catalog Number: (100243-554)
Supplier: Southern Biotechnology
Description: CD45RB represents an exon B-dependent form of CD45 glycoprotein. It is expressed at high density on peripheral B cells, the suppressor/cytotoxic subpopulation of T lymphocytes, a subset of helper T cells, most thymocytes, and at low density on macrophages and dendritic cells.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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