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Catalog Number: (100242-450)
Supplier: Southern Biotechnology
Description: Purified Goat F(ab')2 Anti-Mouse IgM antibody with minimal reactivity to human proteins for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, stimulation, and purification assays.


Catalog Number: (101190-242)
Supplier: Southern Biotechnology
Description: Low Endotoxin/Azide Free Anti-Mouse IFN-gamma antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, ELISA, ELISpot, and neutralization assays.


Catalog Number: (100242-474)
Supplier: Southern Biotechnology
Description: Biotin Anti-Mouse IFN-gamma antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, ELISA, ELISpot, and multiplex assays.


Catalog Number: (103265-592)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Mouse IgG1 antibody for use in ELISA and immunocytochemistry assays.


Catalog Number: (100244-542)
Supplier: Southern Biotechnology
Description: Goat Anti-Rat IgG-TRITC antibody with minimal reactivity to mouse proteins for use in immunohistochemistry / immunocytochemistry assays.


Catalog Number: (103265-272)
Supplier: Southern Biotechnology
Description: CD56, an isoform of the neural cell adhesion molecule (NCAM), is a heavily glycosylated type I transmembrane protein. On human hematopoietic cells its expression is restricted to NK cells and a subpopulation of T lymphocytes (known as large granular lymphocytes) which demonstrate natural killer activity. While it is clear that NCAM plays a role in homotypic adhesion of neuronal cells, the significance of CD56 expression on NK cells is not clear and remains controversial.


Catalog Number: (100245-122)
Supplier: Southern Biotechnology
Description: Rabbit Anti-Sheep IgG(H+L)-TRITC antibody for use in immunohistochemistry / immunocytochemistry assays.


Catalog Number: (103259-878)
Supplier: Southern Biotechnology
Description: FITC Anti-Type I Collagen antibody for use in immunohistochemistry / immunocytochemistry, flow cytometry, and western blotting assays.


Catalog Number: (100245-466)
Supplier: Southern Biotechnology
Description: CD4 is a type I transmembrane glycoprotein expressed on approximately 70% of thymocytes, 10% of spleen cells, and 45% of peripheral blood lymphocytes but less than 1% of bursal cells.


Supplier: Southern Biotechnology
Description: CD56, an isoform of the neural cell adhesion molecule (NCAM), is a heavily glycosylated type I transmembrane protein. On human hematopoietic cells its expression is restricted to NK cells and a subpopulation of T lymphocytes (known as large granular lymphocytes) which demonstrate natural killer activity. While it is clear that NCAM plays a role in homotypic adhesion of neuronal cells, the significance of CD56 expression on NK cells is not clear and remains controversial.

Catalog Number: (100243-026)
Supplier: Southern Biotechnology
Description: CD106, also known as VCAM-1, is an adhesion molecule and a major mediator of the inflammatory response. It is expressed on activated microvascular endothelial cells in response to signals arising from immune responses in infection, graft rejection, tumor recognition and killing. The complementary binding ligand for VCAM-1 is VLA-4/CD49d. In addition to VCAM-1, VLA-4 also recognizes the extracellular matrix molecule fibronectin. This pairing of VCAM-1 and VLA-4 is able to provide a second signal (e.g., non-antigen specific) for T cell stimulation, such as that seen in transplantation. The monoclonal antibody MK-2 has been used in transplant studies to suppress cardiac rejection and induce long-term cardiac graft survival. In addition to inflammatory responses, VCAM-1 has a significant role in hemopoiesis through its ability to retain lymphocyte and myeloid precursors on stromal cells in the marrow and lymphoid organs. CD106/VCAM-1 exists as an integral membrane protein. The M/K-2 monoclonal antibody immunoprecipitates a peptide that gives a single band on SDS-PAGE gels with an apparent Mr of ~100 kDa under reducing conditions and 92 kDa under non-reducing conditions.


Catalog Number: (103265-538)
Supplier: Southern Biotechnology
Description: Glial fibrillary acid protein (GFAP) is a member of the type III intermediate filament family of proteins. GFAP is heavily expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and functions of the cell’s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cell; however, its precise function remains poorly understood. In adults, GFAP levels increase in response to the proliferation of astrocytes associated with Alzheimer’s disease, epilepsy, and multiple sclerosis. Antibodies specific for GFAP are useful as markers of astrocytic cells and neural stem cells as well as for distinguishing neoplasms of astrocytic origin from other neoplasms in the central nervous system.


Supplier: Southern Biotechnology
Description: CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107a is expressed by activated T cells, macrophages, dendritic cells, activated platelets, tonsillar epithelium, and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential where they may increase adhesion to extracellular matrix and endothelium.

Catalog Number: (100243-004)
Supplier: Southern Biotechnology
Description: Fibronectin is a high molecular weight dimeric glycoprotein which is present in soluble and insoluble forms. The soluble form is the major component of blood plasma and is mainly produced by hepatocytes while insoluble fibronectin is a major component of the extracellular matrix. Fibronectin is involved in cell adhesion, growth, migration, and differentiation.


Catalog Number: (103260-118)
Supplier: Southern Biotechnology
Description: Anti-Biotin may be used for indirect immunostaining when working with a biotinylated primary antibody. As an effective alternative to avidin, Anti-Biotin amplifies signal and reduces background that can be caused by avidin and its derivatives.


Catalog Number: (100242-964)
Supplier: Southern Biotechnology
Description: Biotin Anti-Type I Collagen antibody for use in ELISA, immunohistochemistry / immunocytochemistry, electron microscopy, flow cytometry, western blotting, and immunoprecipitation assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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