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Image Unavailable-100243-194

Anti-CD11a Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: I21/7]

Catalog Number: (100243-194)
Supplier: Southern Biotechnology
Description: The monoclonal antibody I21/7 reacts with the α subunit of mouse and human CD11a, also known as LFA-1, and a member of the integrin family of cell adhesion molecules. The antigen is expressed on thymocytes, T and B lymphocytes, and on non-lymphoid cells in the bone marrow. CD11a appears to be an essential component for T-cell activation by antigen-presenting cells and is important for cell-mediated killing. Costimulatory signaling by LFA-1 is achieved by pairing with its ligand, CD54/ICAM-1.
Image Unavailable-100243-134

Anti-CD4 Rat Monoclonal Antibody (RPE (R-Phycoerythrin)/Cy7®) [clone: GK1.5]

Catalog Number: (100243-134)
Supplier: Southern Biotechnology
Description: CD4 is a type I transmembrane glycoprotein expressed on most thymocytes and the helper/inducer subpopulation of mature T lymphocytes of all mouse strains tested. CD4 has also been detected at low density on pluripotent hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic lymphoid precursors. The CD4 antigen functions as a co-receptor, interacting with class II major histocompatability complex (MHC) molecules in the recognition of foreign antigens by T cells. In vivo and in vitro treatment with the GK1.5 monoclonal antibody effectively depletes CD4+ cells. GK1.5 also blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.
Image Unavailable-103264-210

Anti-Ig Goat Antibody (Alexa Fluor® 555)

Catalog Number: (103264-210)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Mouse Ig-Alexa Fluor 555 antibody with minimal reactivity to human proteins for use in immunocytochemistry and western blotting assays.
Image Unavailable-100245-096

Anti-IgG (H+L) Rabbit Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (100245-096)
Supplier: Southern Biotechnology
Description: Rabbit F(ab')2 Anti-Rat IgG(H+L)-HRP antibody with minimal reactivity to human proteins for use in ELISA and immunocytochemistry assays.
Image Unavailable-100244-966

Anti-IgG (H+L) Goat Antibody

Catalog Number: (100244-966)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Equine IgG(H+L) antibody for use in ELISA, flow cytometry, immunocytochemistry, and western blotting assays.
Image Unavailable-100244-354

Anti-Kappa Goat Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (100244-354)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Human Kappa-FITC antibody for use in flow cytometry, immunocytochemistry, and western blotting assays.
Image Unavailable-100245-650

Anti-IgM Mouse Antibody (APC (Allophycocyanin)) [clone: SA-DA4]

Catalog Number: (100245-650)
Supplier: Southern Biotechnology
Description: APC Anti-Human IgM antibody for use in flow cytometry assays.
Image Unavailable-100244-158

Anti-H-2Kk Mouse Monoclonal Antibody (RPE (R-Phycoerythrin)) [clone: 36-7-5]

Catalog Number: (100244-158)
Supplier: Southern Biotechnology
Description: The monoclonal antibody 36-7-5 reacts with the H-2Kk MHC class I alloantigen. Cross-reactivity with splenocytes of SJL/Hsd mice has been observed by flow cytometry. The antibody does not react with other (e.g., b, d, q) haplotypes.
Image Unavailable-103264-934

Anti-IgG (H+L) Rabbit Antibody (AP (Alkaline Phosphatase))

Catalog Number: (103264-934)
Supplier: Southern Biotechnology
Description: Rabbit F(ab')2 Anti-Sheep IgG(H+L)-AP antibody with minimal reactivity to human serum proteins for use in ELISA assays.
Image Unavailable-103264-394

Anti-IgG F(c) Goat Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (103264-394)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG Fc-HRP antibody for use in ELISA and western blotting assays.
Image Unavailable-100243-616

Anti-CD69 Hamster Monoclonal Antibody (Spectral Red® RPE (R-Phycoerythrin)/Cy5®) [clone: H1.2F3]

Catalog Number: (100243-616)
Supplier: Southern Biotechnology
Description: CD69, also known as very early activation (VEA) antigen, is a disulfide-linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa. It is a C-type lectin most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. CD69 is widely expressed on hematopoietic cells, including lymphocytes, neutrophils and eosinophils. Although not detectable on resting lymphocytes, its expression is rapidly upregulated upon activation of T, B and NK cells, and neutrophils. Constitutive expression of CD69 on subsets of thymocytes suggests that it may be involved in regulation of developmental events in addition to its role in activation of a variety of hematopoietic cells. The monoclonal antibody H1.2F3 augments PMA-induced T-cell proliferation and induces redirected lysis of Fc receptor-bearing target cells by NK cells.
Image Unavailable-100246-106

Anti-CD8 Mouse Monoclonal Antibody (Biotin) [clone: RFT8]

Catalog Number: (100246-106)
Supplier: Southern Biotechnology
Description: CD8 is a 33 kDa transmembrane glycoprotein expressed as either a CD8αα homodimer or CD8αβ heterodimer. It is expressed on the “cytotoxic/suppressor” subpopulation of peripheral T cells. CD8 functions primarily as a coreceptor with MHC class I-restricted TCR’s in antigen recognition.
Image Unavailable-100243-732

Anti-BP-1 Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: FG35.4]

Catalog Number: (100243-732)
Supplier: Southern Biotechnology
Description: BP-1, also known as Ly-51 and 6C3 antigen, is a type II homodimeric transmembrane glycoprotein formed by two disulfide-linked chains of 140 kDa. Originally identified on the surface of pre-B cell lymphomas the cDNA encoding BP-1 has been cloned and found to represent aminopeptidase A. It is expressed at high levels on bone marrow stromal cell lines which support in vitro B lymphopoiesis and on a wide variety of mouse tissues known to possess aminopeptidase activity. Subsets of normal bone marrow pre-B and B cells express low levels of BP-1 which is rapidly upregulated on pre-B cells in the presence of IL-7. The BP-1 marker is commonly used to identify B cells in different stages of development.
Image Unavailable-101442-546

Rat IgG2a Isotype Control [clone: KLH/G2a-1-1] (APC (Allophycocyanin)/Cy5.5®)

Catalog Number: (101442-546)
Supplier: Southern Biotechnology
Description: Rat IgG2a-APC/CY5.5 for use as a control in flow cytometry assays.
Image Unavailable-103259-616

Mouse IgG1 Isotype Control [clone: 15H6] (Alexa Fluor® 488)

Catalog Number: (103259-616)
Supplier: Southern Biotechnology
Description: Mouse IgG1-Alexa Fluor 488 for use as a control in flow cytometry and immunohistochemistry / immunocytochemistry assays.
Image Unavailable-100243-576

Anti-CD49e Rat Monoclonal Antibody [clone: 5H10.27]

Catalog Number: (100243-576)
Supplier: Southern Biotechnology
Description: The monoclonal antibody 5H10.27 reacts with the α5 chain (VLA-5) of the CD49e/CD29 heterodimeric fibronectin receptor. It is expressed on thymocytes, activated T cells, mast cells, and a variety of mouse cell lines. Soluble 5H10.27 antibody inhibits VLA-5-mediated functions in vitro. Immobilized 5H10.27 has also been demonstrated to costimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3 monoclonal antibody.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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