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Description: Alexa Fluor 647 Anti-Mouse IL-2 antibody for use in flow cytometry and immunohistochemistry assays.
Catalog Number: 103265-490
Supplier: Southern Biotechnology


Description: Purified Goat F(ab')2 Anti-Mouse IgG(H+L) antibody with minimal reactivity to human proteins for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.
Catalog Number: 100242-520
Supplier: Southern Biotechnology


Description: CD57 represents a 110 kDa oligosaccharide antigenic determinant present on a variety of polypeptides, lipids, and chondroitan sulfate proteoglycans. It is expressed on 7-35% of normal peripheral blood lymphocytes, including subsets of NK cells and CD8+ T lymphocytes. The carbohydrate is expressed on various cell adhesion molecules in the nervous system and is suggested to play a role in cell–cell and cell–substrate interactions.
Catalog Number: 100246-342
Supplier: Southern Biotechnology


Description: The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity α chain of the IL-2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O-linked carbohydrates and has a short cytoplasmic tail. CD25 is expressed on activated T cells, B cells, NK cells, and monocytes of all mouse strains tested. It is transiently expressed at a low level during B cell development in bone marrow on the CD45R/B220low TdT- sIg- pre-B II and CD45R/B220low TdT- sIgM+sIgD- immature B cells, but not on the CD45R/B220low TdT+ sIg- pro-B/pre-B I stage nor on CD45R/B220high TdT- sIgM+sIgD+ mature B cells. CD25 is expressed at a higher level during very early T-cell development in fetal and adult thymus. The 7D4 monoclonal antibody reacts with an epitope between amino acids 125 and 212 that is distinct from that recognized by the monoclonal antibody 3C7 (SB Cat. No. 1600). While the monoclonal antibody 7D4 does not block the binding of IL-2 to CD25, when used in combination with the monoclonal antibody 3C7 it results in higher levels of inhibition of IL-2-driven proliferation than either of these two monoclonal antibodies alone.
Catalog Number: 100243-340
Supplier: Southern Biotechnology


Description: CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.
Catalog Number: 103265-390
Supplier: Southern Biotechnology


Description: Rat IgG2a-PE for use as a control in flow cytometry assays.
Catalog Number: 100242-088
Supplier: Southern Biotechnology


Description: Mouse IgG-PE/CY5 (SPRD) for use as a control in flow cytometry assays.
Catalog Number: 100241-996
Supplier: Southern Biotechnology


Description: Rabbit F(ab')2 Anti-Rat IgG(H+L)-AP antibody with minimal reactivity to human proteins for use in ELISA and immunocytochemistry assays.
Catalog Number: 100245-094
Supplier: Southern Biotechnology


Description: CD22, also known as Lyb-8, is a heterodimeric transmembrane glycoprotein and a member of a structurally related group of immunoglobulin (Ig) superfamily domain-containing proteins called the sialoadhesin family. It is detected in the cytoplasm early in B cell development (late pro-B cell stage), appears on the cell surface concomitant with IgD, and is found on most IgM+IgD+ mature B lymphocytes. Expression is lost with terminal differentiation of B cells and is absent on plasma cells. Activation of B cells via cross-linking of surface Ig increases CD22 expression. CD22 associates with the B cell receptor (BCR) complex and mediates intercellular adhesion. Its intracellular domain is phosphorylated after antigen receptor cross-linking and is involved in negative regulation of B cell activation.
Catalog Number: 100243-302
Supplier: Southern Biotechnology


Description: Goat F(ab')2 Anti-Rat IgG-Texas Red antibody with minimal reactivity to mouse proteins for use in flow cytometry and immunohistochemistry assays.
Catalog Number: 100244-562
Supplier: Southern Biotechnology


Description: CD5, a member of the scavenger receptor superfamily of cell surface receptors, is a type I transmembrane glycoprotein whose ligand is CD72. It is expressed on most thymocytes, all mature T cells, and a subset of B cells. CD5 plays a role in regulation of T cell activation and signaling.
Catalog Number: 103260-198
Supplier: Southern Biotechnology


Description: CD10, also known as the common acute lymphoblastic leukemia antigen (CALLA), is a type II transmembrane glycoprotein. It is expressed on granulocytes, a subset of B progenitor cells, germinal center cells, and fibroblasts. CD10 is a zinc-binding metalloprotease which is thought to down-regulate cellular responses to peptide hormones.
Catalog Number: 101442-948
Supplier: Southern Biotechnology


Description: Goat F(ab')2 Anti-Mouse IgG(H+L)-PE antibody with minimal reactivity to human proteins for use in flow cytometry assays.
Catalog Number: 100242-530
Supplier: Southern Biotechnology


Description: CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B-cell specific stimuli with peak expression at 18-42 hours after stimulation. CD86, along with CD80 (B7-1), is an important accessory molecule in T cell costimulation via its interaction with CD28 and CD152 (CTLA-4). Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. The monoclonal antibody GL1 blocks mixed lymphocyte reactions and stimulation of T cells by antigen-presenting cells.
Catalog Number: 100243-660
Supplier: Southern Biotechnology


Description: Alexa Fluor 488 Anti-Human IgG4 pFc' antibody for use in flow cytometry, immunohistochemistry, and western blotting assays.
Catalog Number: 103265-216
Supplier: Southern Biotechnology


Description: Goat F(ab')2 Anti-Mouse IgG(H+L)-Alexa Fluor 488 antibody with minimal reactivity to human proteins for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
Catalog Number: 103264-386
Supplier: Southern Biotechnology


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