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Catalog Number: (100244-958)

Supplier: Southern Biotechnology

Description: Purified Goat Anti-Bovine IgG(H+L) antibody for use in ELISA, flow cytometry, immunocytochemistry, western blotting, immunoprecipitation, and purification assays and for immobilization in surface plasmon resonance.

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Catalog Number: (100245-682)

Supplier: Southern Biotechnology

Description: Purified Anti-Human IgG Fc antibody for use in ELISA, flow cytometry, immunohistochemistry, western blotting, and multiplex assays.

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Catalog Number: (100243-290)

Supplier: Southern Biotechnology

Description: CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow.

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Catalog Number: (100243-908)

Supplier: Southern Biotechnology

Description: CD103 is a member of the integrin series of adhesion molecules. This antigen defines a developmentally important subset of T cells, namely mucosal T cells including all IEL (intraepithelial lymphocytes) and ~20% of lamina propria T cells. Expression of CD103 is more restricted outside these mucosal organs appearing at lower levels on T cell subsets of the lymph node, dendritic epidermis, and periphery. In non-epithelial CD103+ T cells there is a bias toward expression on CD8+ cells. The 2E7 monoclonal antibody exhibits antigen immunoprecipitation patterns similar if not identical to the rat anti-mouse CD103 monoclonal antibody M290. 2E7 is reported to have signal-inducing activity in a redirected lysis assay and to costimulate IEL and CD8+ lymph node cells in conjunction with anti-TCR in vitro which runs counter to the usual inhibition of CTL by anti-integrins. This costimulatory activity is also shared by the monoclonal antibody M290. The property of costimulation is not unique to the mouse since the combination of anti-human αIEL plus anti-TCR will produce similar proliferation in human cells with the exception that CD8+ cells are not stimulated.

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Catalog Number: (100245-002)

Supplier: Southern Biotechnology

Description: Goat Anti-Hamster IgG(H+L)-AP antibody with minimal reactivity to mouse and rat proteins for use in ELISA, immunohistochemistry, and western blotting assays.

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Catalog Number: (103264-844)

Supplier: Southern Biotechnology

Description: Alexa Fluor 488 Anti-Rat IgG2b antibody for use in flow cytometry, immunohistochemistry, and western blotting assays.

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Catalog Number: (100245-206)

Supplier: Southern Biotechnology

Description: Goat Anti-Rhesus IgG(H+L)-TRITC antibody for use in immunocytochemistry assays.

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Catalog Number: (100245-462)

Supplier: Southern Biotechnology

Description: CD4 is a type I transmembrane glycoprotein expressed on approximately 70% of thymocytes, 10% of spleen cells, and 45% of peripheral blood lymphocytes but less than 1% of bursal cells.

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Catalog Number: (101442-952)

Supplier: Southern Biotechnology

Description: CD13, also known as aminopeptidase N, is a 150 kDa type II integral membrane glycoprotein. It is expressed on granulocytes, monocytes and their precursors, and on mast cells. CD13 is a zinc-binding metalloprotease that is involved in cell surface antigen presentation via its digestion of many MHC-bound regulatory peptides.

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Catalog Number: (103264-478)

Supplier: Southern Biotechnology

Description: Purified Anti-Mouse IgM antibody for use in ELISA, flow cytometry, immunohistochemistry, and western blotting assays.

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Catalog Number: (103259-856)

Supplier: Southern Biotechnology

Description: HRP Anti-Mouse IgG2b antibody for use in ELISA, immunocytochemistry, and western blotting assays.

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Catalog Number: (100244-120)

Supplier: Southern Biotechnology

Description: The monoclonal antibody 27-11-13S recognizes with the α3 domain of H-2Db class I MHC antigen. The antibody cross-reacts with the α3 domain of H-2Dd, H-2Dq, H-2Ld and H-2Lq but not H-2Kb. Reactivity with haplotypes k, f, p, r, and s has not been observed.

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Supplier: Southern Biotechnology

Description: CD45, also known as the leukocyte common antigen (LCA), exists as four different isoforms (180, 190, 205, 220 kDa) that are generated by alternative splicing of three exons. LCA is found on all cells of hematopoietic origin, except erythrocytes and platelets. CD45 expression is required for T cell and B cell antigen receptor-mediated activation.

Catalog Number: (103265-360)

Supplier: Southern Biotechnology

Description: CD16, a member of the immunoglobulin superfamily, is a 50-65 kDa glycoprotein found as both a transmembrane and GPI-linked form. The transmembrane form of CD16 is expressed on NK cells, granulocytes, macrophages, and mast cells but not on eosinophils. The GPI-anchored type of CD16 is found only on neutrophils. CD16 is involved in NK activation and signal transduction.

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Catalog Number: (100242-502)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG(H+L)-AP antibody with minimal reactivity to human proteins for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.

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Catalog Number: (103264-614)

Supplier: Southern Biotechnology

Description: Ly-6C is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T-cell subsets. Mice with the Ly-6.2 allotype (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have subsets of CD4+Ly-6C+ and CD8+Ly-6C+ cells while Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+Ly-6C+ lymphocytes. Ly-6C may play a role in the development and maturation of lymphocytes.

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