You Searched For: DuPont+Tychem®+2000

Catalog Number: (103259-952)

Supplier: Southern Biotechnology

Description: CD90 (Thy-1) is a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily consisting of a single V-set domain. The Thy-1.2 alloantigen is expressed on all thymocytes, peripheral T lymphocytes, and some intraepithelial T cells of most mouse strains. It is also expressed in the brain and at varying levels on other non-lymphoid tissues. The 30-H12 monoclonal antibody does not cross react with mouse and rat strains bearing the Thy-1.1 alloantigen (e.g., AKR/J, PL).

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Supplier: Southern Biotechnology

Description: CD14 is a 55 kDa glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells, and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.

Catalog Number: (103265-146)

Supplier: Southern Biotechnology

Description: CD3 is a member of the T cell receptor-associated CD3 complex. The monoclonal antibody CT-3 recognizes a complex of at least three polypeptides of Mr 20, 19, and 17 kDa (two of which are N-glycosylated) on chicken T cells. The antibody also coprecipitates a polypeptide of 90 kDa from digitonin solubilized T cell lysates, which can be reduced to two polypeptides of Mr 50 and 40 kDa.

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Catalog Number: (100244-826)

Supplier: Southern Biotechnology

Description: Porcine CD3ε is a member of the T-cell receptor-associated CD3 complex. It is found on a subpopulation of thymocytes and on all pig T lymphocytes. The monoclonal antibody PPT3 is mitogenic when presented to peripheral blood mononuclear cells in immobilized form.

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Catalog Number: (103264-542)

Supplier: Southern Biotechnology

Description: CD4 is a type I transmembrane glycoprotein expressed on most thymocytes and the helper/inducer subpopulation of mature T lymphocytes of all mouse strains tested. CD4 has also been detected at low density on pluripotent hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic lymphoid precursors. The CD4 antigen functions as a co-receptor, interacting with class II major histocompatability complex (MHC) molecules in the recognition of foreign antigens by T cells. In vivo and in vitro treatment with the GK1.5 monoclonal antibody effectively depletes CD4+ cells. GK1.5 also blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.

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Catalog Number: (100243-882)

Supplier: Southern Biotechnology

Description: The monoclonal antibody DX5 reacts with CD49b, also known as very late antigen-2 (VLA-2) and α2 integrin. The antibody stains the majority of NK cells and a small subpopulation of T cells in all mouse strains tested (e.g., A/J, AKR, BALB/c, C3H/HeJ, C57BL/6, C57BL/10, C57BR, C58, CBA/Ca, CBA/J, DBA/1, DBA/2, SJL, SWR). Three-color flow cytometry analysis has revealed that most cells that express NK-1.1 (NKR-P1C) also express CD49b. However, small subsets of DX5+NK-1.1- and DX5-NK-1.1+ cells can be found, especially among the CD3+ population of T lymphocytes. NK cells cultured in the presence of IL-2 progressively lose reactivity with DX5 as a consequence of cellular proliferation. Therefore, DX5 can be used to define functionally distinct subsets of murine NK cells. The monoclonal antibody DX5 has not been demonstrated to have activating or blocking activity.

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Catalog Number: (100242-284)

Supplier: Southern Biotechnology

Description: Purified Anti-Human IL-10 antibody for use in immunohistochemistry, ELISA, ELISpot, and western blotting assays.

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Catalog Number: (100242-470)

Supplier: Southern Biotechnology

Description: Biotin Anti-Mouse GM-CSF antibody for use in immunohistochemistry / immunocytochemistry, ELISA, immunoprecipitation, and multiplex assays.

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Catalog Number: (103260-100)

Supplier: Southern Biotechnology

Description: Purified Rabbit Anti-Hamster IgG(H+L) antibody with minimal reactivity to mouse and rat serum proteins for use in ELISA, flow cytometry, immunohistochemistry, and western blotting assays.

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Catalog Number: (100245-022)

Supplier: Southern Biotechnology

Description: Purified Goat Anti-Canine IgG(H+L) antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.

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Catalog Number: (103265-244)

Supplier: Southern Biotechnology

Description: Alexa Fluor 647 Anti-Human Kappa antibody for use in flow cytometry assays.

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Catalog Number: (101190-222)

Supplier: Southern Biotechnology

Description: Human IgG1 Kappa-PE for use as a control in flow cytometry assays.

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Catalog Number: (100244-592)

Supplier: Southern Biotechnology

Description: PE Anti-Rat IgG1 antibody for use in flow cytometry assays.

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Supplier: Southern Biotechnology

Description: CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.

Catalog Number: (100242-746)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG3-Biotin antibody with minimal reactivity to human proteins for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.

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Catalog Number: (103259-854)

Supplier: Southern Biotechnology

Description: AP Anti-Mouse IgG2b antibody for use in ELISA,, immunocytochemistry, and western blotting assays.

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