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Catalog Number: (100242-698)
Supplier: Southern Biotechnology
Description: Goat F(ab’)2 Anti-Mouse IgG2a-FITC antibody with minimal reactivity to human proteins for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.


Catalog Number: (101442-506)
Supplier: Southern Biotechnology
Description: Mouse IgG2a-APC/CY5.5 for use as a control in flow cytometry assays.


Catalog Number: (103265-262)
Supplier: Southern Biotechnology
Description: CD54, also known as intercellular cell adhesion molecule-1 (ICAM-1), is a 90 kDa type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It exhibits a wide tissue distribution being expressed on both hematopoietic and non-hematopoietic cells. ICAM-1 expression on leukocytes is low but is rapidly upregulated upon activation. Expression on endothelium and other non-hematopoietic cells is strongly upregulated by inflammatory mediators. The ligands of CD54 are CD11a/LFA-1α and CD11b/Mac-1α. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels particularly in areas of inflammation. CD54 on antigen-presenting cells (APC) contributes to antigen-specific T cell activation presumably by enhancing interactions between T cells and APC.


Catalog Number: (100245-280)
Supplier: Southern Biotechnology
Description: Donkey Anti-Rat IgG(H+L)-HRP antibody with minimal reactivity to mouse serum proteins for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100242-766)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgE-Biotin antibody for use in ELISA, flow cytometry, immunocytochemistry, western blotting, and immunoprecipitation assays.


Catalog Number: (103264-786)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgG-HRP antibody with minimal reactivity to rhesus and cynomolgus proteins for use in ELISA assays.


Catalog Number: (101190-268)
Supplier: Southern Biotechnology
Description: FITC Anti-Human TLR2 antibody for use in flow cytometry assays.


Catalog Number: (103259-676)
Supplier: Southern Biotechnology
Description: Interleukin-21 (IL-21) is a four helical bundle type I cytokine. The mature form of human IL-21 is a 131 amino acid protein. IL-21 is expressed primarily by NKT and CD4+ T cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. The effects of IL-21 include promotion of antibody production, NK cell differentiation, proliferation and differentiation of cells of monocyte and granulocyte lineages, costimulation of T cells, and augmentation of antitumor activity of CD8+ T cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation and suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.


Catalog Number: (100244-140)
Supplier: Southern Biotechnology
Description: CD86 (B7-2) is an 80 kDa type I integral membrane protein and a member of the immunoglobulin superfamily of cell surface receptors. Along with CD80 (B7-1), CD86 participates in T cell costimulation via interaction with CD28 and CD152 (CTLA-4). It is expressed at very low density in normal tissues but is rapidly upregulated on stimulated B cells, monocytes, and dendritic cells. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.


Catalog Number: (101442-972)
Supplier: Southern Biotechnology
Description: CD42b, also known as GPIbα, is a two-chain membrane glycoprotein that forms a noncovalent complex with CD42a (GPIX) on the surface of platelets and megakaryocytes. Binding of the GPIb/GPIX heterodimer to von Willebrand factor bound to exposed subendothelial surfaces is essential for platelet adhesion at sites of injury.


Catalog Number: (100245-624)
Supplier: Southern Biotechnology
Description: ChT1, a member of the Ig superfamily with one V-like and one C2-like domain, is a T cell antigen that is expressed on the surface of embryonic thymocytes (day 10). In young chickens about 90% of the thymocytes as well as a subpopulation of peripheral lymphocytes, which represent recent thymic emigrants are ChT1 positive. Expression in the periphery declines with age and, in correlation with partial thymectomy, indicates that ChT1 can be used as an accurate marker for studying thymic function. The monoclonal antibody CT1 also recognizes the ChT1 antigen in quail cortical thymocytes.


Catalog Number: (103265-326)
Supplier: Southern Biotechnology
Description: CD14 is a 55 kDa glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells, and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.


Catalog Number: (100244-014)
Supplier: Southern Biotechnology
Description: The monoclonal antibody NIMR-4 reacts specifically with a non-polymorphic I-A-encoded epitope on MHC Class II antigens. Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells, and certain epithelial cells.


Catalog Number: (100242-714)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG2b-Texas Red antibody with minimal reactivity to human proteins for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.


Supplier: Southern Biotechnology
Description: CD4 is a 55 kDa type I transmembrane glycoprotein and a member of the Ig-SF of cell surface receptors. It is expressed predominantly on the “helper/inducer” subpopulation of mature T lymphocytes and on monocytes and macrophages. Domains 1 and 2 bind to MHC Class II antigens, while domains 3 and 4 may be involved in cis interactions with the CD3/TCR complex. CD4 functions as an accessory molecule in the recognition of foreign antigens in association with MHC class II antigens by T cells.

Catalog Number: (100245-678)
Supplier: Southern Biotechnology
Description: Biotin Anti-Human IgD antibody for use in ELISA, flow cytometry, immunohistochemistry, immunoprecipitation, and separation assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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