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Description: Rat IgG1-APC for use as a control in flow cytometry assays.
Catalog Number: 100242-074
Supplier: Southern Biotechnology


Description: Biotin Anti-Goat IgG Fc antibody for use in ELISA, immunohistochemistry, and western blotting assays.
Catalog Number: 103264-996
Supplier: Southern Biotechnology


Description: CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes, and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN γ, IL-1, TNF-α, lipopolysaccharide, and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1.
Catalog Number: 100243-582
Supplier: Southern Biotechnology


Description: Purified Goat Anti-Mouse IgG2a antibody with minimal reactivity to human, bovine, and horse serum proteins for use in ELISA assays.
Catalog Number: 103259-792
Supplier: Southern Biotechnology


Description: Biotin Anti-Mouse IL-10 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, ELISA, and ELISpot assays.
Catalog Number: 100242-436
Supplier: Southern Biotechnology


Description: CD49f is the 125 kDa integrin α6 chain which associates noncovalently with the integrin β1 subunit (CD29) and with the integrin β4 (CD104) chain to form, respectively, the very late antigen-6 (VLA-6) and α6β4 integrin heterodimers. VLA-6 is expressed on thymocytes, T lymphocytes, monocytes, and platelets. CD49f/CD29 expression is upregulated on activated T lymphocytes and memory T cells. VLA-6 serves as the laminin receptor on platelets, monocytes, and T cells. VLA-6-mediated binding to laminin provides a costimulatory signal to T cells for activation and proliferation.
Catalog Number: 100246-302
Supplier: Southern Biotechnology


Description: CD61 is the integrin β3 subunit, a 110 kDa transmembrane glycoprotein expressed on platelets, megakaryocytes, and endothelial cells. Integrin β3 associates with gpIIb (CD41) to form the CD41/CD61 complex that mediates platelet adhesion and aggregation. CD61 also associates with CD51 to form the αVβ3 vitronectin receptor.
Catalog Number: 103265-276
Supplier: Southern Biotechnology


Description: AP Anti-Human IgG1 Hinge antibody for use in ELISA, immunohistochemistry, and western blotting assays.
Catalog Number: 100245-714
Supplier: Southern Biotechnology


Description: Low Endotoxin/Azide Free Anti-Mouse TNF-alpha antibody for use in flow cytometry, immunohistochemistry, western blotting, ELISA, ELISpot, and neutralization assays.
Catalog Number: 101190-238
Supplier: Southern Biotechnology


Description: In the chicken, the CD8 molecule is present in two forms - (i) a homodimer of two α chains and (ii) a heterodimer of an α chain and a β chain. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8α- and CD8β-chains, a relatively large proportion of the CD8+ TCR-γδ cells in the spleens of embryos and young chicks express only the α-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved but there is a population of TCR-γδ CD8αβ cells in the chicken that is not found in rodents. Chicken CD8 is expressed on approximately 80% of thymocytes, 45% of blood mononuclear cells, and 50% of spleen cells but less than 1% of cells in the bursa and bone marrow. The monoclonal antibody EP42 recognizes the CD8β chain.
Catalog Number: 100245-488
Supplier: Southern Biotechnology


Description: Purified Goat Anti-Human IgG Fc antibody for use in ELISA and western blotting assays and for immobilization in surface plasmon resonance.
Catalog Number: 103265-650
Supplier: Southern Biotechnology


Description: Goat Anti-Rat IgM-Alexa Fluor 488 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
Catalog Number: 103264-810
Supplier: Southern Biotechnology


Description: CD158e1 is a 70 kDa transmembrane glycoprotein and a killer cell immunoglobulin (Ig)-like receptor (KIR) that is expressed on a subset of natural killer cells and T cells. The monoclonal antibody DX9 is expressed on a subset of CD3-, CD56+ NK cells isolated from peripheral blood at varying levels (<0.1% to 61%) among individuals but not on thymocytes, B lymphocytes, granulocytes, or monocytes. Interactions with CD158e1 and certain MHC HLA-B antigens on a target cell inhibits cytotoxicity, possibly preventing target cell lysis and death. KIR and MHC class I interactions may regulate NK and T cell response to antigen stimulation.
Catalog Number: 103265-444
Supplier: Southern Biotechnology


Description: CD14 is a 55 kDa glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells, and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.
Catalog Number: 103265-332
Supplier: Southern Biotechnology


Description: Goat Anti-Bovine Human Albumin-Biotin antibody with minimal reactivity bovine serum albumin for use in ELISA assays.
Catalog Number: 103260-040
Supplier: Southern Biotechnology


Description: The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity α chain of the IL-2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O-linked carbohydrates and has a short cytoplasmic tail. CD25 is expressed on activated T cells, B cells, NK cells, and monocytes of all mouse strains tested. It is transiently expressed at a low level during B cell development in bone marrow on the CD45R/B220low TdT- sIg- pre-B II and CD45R/B220low TdT- sIgM+sIgD- immature B cells, but not on the CD45R/B220low TdT+ sIg- pro-B/pre-B I stage nor on CD45R/B220high TdT- sIgM+sIgD+ mature B cells. CD25 is expressed at a higher level during very early T-cell development in fetal and adult thymus. The 7D4 monoclonal antibody reacts with an epitope between amino acids 125 and 212 that is distinct from that recognized by the monoclonal antibody 3C7 (SB Cat. No. 1600). While the monoclonal antibody 7D4 does not block the binding of IL-2 to CD25, when used in combination with the monoclonal antibody 3C7 it results in higher levels of inhibition of IL-2-driven proliferation than either of these two monoclonal antibodies alone.
Catalog Number: 100243-352
Supplier: Southern Biotechnology


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