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Catalog Number: (10049-588)
Supplier: Enzo Life Sciences
Description: TPPP plays a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. Plays a role in mitotic spindle assembly and nuclear envelope breakdown.


Supplier: Enzo Life Sciences
Description: A potent and selective vanilloid receptor (TRPV1) antagonist. An effective antagonist of hTRPV1 when stimulated by capsaicin, acid, or noxious heat.

Catalog Number: (10049-612)
Supplier: Enzo Life Sciences
Description: DcR1 is a 65kDa GPI-anchored member of the TNFR superfamily (TNFRSF10C) also known as TRAIL-R3, TRID, CD263, and LIT. Although not expressed by most tumors, DcR1 is expressed at low levels on normal tissues, acting as a TRAIL decoy receptor, thus inhibiting apoptosis. DcR1 is termed a decoy receptor, as it does not have a functional death domain to induce apoptosis following TRAIL ligation.


Catalog Number: (10049-846)
Supplier: Enzo Life Sciences
Description: SARM (SAM and ARM-containing protein) is thought to serve as an adaptor protein for the Toll-like receptors (TLRs) and allow for the activation of downstream kinases and NF-κB, ultimately leading to the expression of proteins involved in host defense. While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interleukin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule.


Catalog Number: (89158-676)
Supplier: Enzo Life Sciences
Description: Host: Rabbit


Catalog Number: (89163-908)
Supplier: Enzo Life Sciences
Description: Produced in <i>E.coli.</i> Active Matrix Metalloproteinase-14 (MMP-14, Membrane-Type Matrix Metalloproteinase 1, MT1-MMP) catalytic domain from human cDNA. The enzyme consists of the catalytic domain of human MMP-14 (Tyr112-Arg298, NM_004995) with a C-terminal purification tag. This represents a naturally-occurring active form of MMP-14 which lacks the C-terminal hemopexin domain. MMPs lacking this domain cannot cleave native collagens; however, activity toward other targets such as gelatin, casein, or peptide substrates is unaffected.


Supplier: Enzo Life Sciences
Description: Necrosis inhibitor.

Catalog Number: (76014-146)
Supplier: Enzo Life Sciences
Description: Recommended Applications: ICC, IHC (FS), IHC (PS), WB

Species reactivity: Human, Mouse


Catalog Number: (89160-280)
Supplier: Enzo Life Sciences


Catalog Number: (89152-786)
Supplier: Enzo Life Sciences
Description: TLR4 activator.


Supplier: Enzo Life Sciences
Description: Specific, potent and membrane permeant activator of the Epac cAMP receptor.

Catalog Number: (10049-366)
Supplier: Enzo Life Sciences
Description: The IHC wash buffer is a for washing and removing excess reagents during immunostaining.


Supplier: Enzo Life Sciences
Description: PARP5a inhibitor

Catalog Number: (89153-866)
Supplier: Enzo Life Sciences
Description: Mammalian apurinic/apyrimidinic (AP) endonuclease (APE1; APEX; HAP1; Ref-1) is a multifunctional, bipartite enzyme that belongs to the class II AP endonucleases and that plays an important role in numerous, cellular functions, like repairing abasic sites (loss of purine or pyrimidine base) in DNA, regulating the redox state of other proteins that play roles in oxidative signalling, transcription factor regulation (Fos, Jun, NF-κ B, Myb, HIF-1α, CREB, Pac), cell cycle control (p53) and apoptosis. APE1 initiates the DNA base excision repair (BER) by cleaving the DNA immediately adjacent to the 5’ of an AP site to produce a hydroxyl group at the 3’ terminus of an unmodified nucleotide upstream of the nick and a 5’-deoxyribose phosphate moiety downstream. The product of APE1 is further processed by DNA polymerase β to release 5’-deoxyribose phosphate with its intrinsic lyase activity. The nicked DNA is then sealed by DNA ligase I or DNA ligaseIII/XRCC1 to complete this repair process. In addition to the AP endonuclease activity, APE1 also possesses a 3’-5’ DNA exonuclease activity, a 3’-phosphodiesterase activity, a 3’-phosphatase activity, and a RNase H activity. It has been shown that APE1 is capable of excision L-configuration deoxyribonucleoside analogs from the 3’ termini of DNA. Human APE1 gene is located on chromosome 14q 11.2-12.


Supplier: Enzo Life Sciences
Description: Potent inhibitor of phosphatidic acid generation

Catalog Number: (76002-798)
Supplier: Enzo Life Sciences
Description: Recommended Applications: ELISA, ICC, IHC, WB

Species reactivity: Human, Xenopus, Mammalian, Chicken


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