XAV939 ≥98% (by TLC)
Supplier: SAFE AND SURE NEDERLAND B.V.
Ratings:
(No Reviews)
Total Ratings: 0
Avg. Ratings: 0.0 out of 5
BML-WN100-0005
BML-WN100-0025
76002-190EA
80.66
USD
76002-190
76002-192
XAV939 ≥98% (by TLC)
XAV939
PARP5a inhibitor
Potent inhibitor of Tankyrase 1 (IC50=11nM) and Tankyrase 2 (IC50=4nM). Inhibition of tankyrase promotes stabilization of axin resulting in β-catenin degradation and Wnt signalling disruption. Inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1. Promotes cardiomyogenic development in mesoderm progenitor cells.
Formula:
C₁₄H₁₁F₃N₂OS |
MDL Number:
MFCD16879017 CAS Number: 284028-89-3 |
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