You Searched For: VEL CHEMICALS DECONDITIONERING

Description: DNMT colorimetric drug discovery kit is a simple method to detect DNA methylation activity or inhibition.

Catalog Number: 10135-968

Supplier: Enzo Life Sciences

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Description: The lymphocyte activation gene-3 (LAG-3, CD223), a member of the immunoglobulin superfamily (IgSF) related to CD4, binds to the major histocompatibility complex (MHC) class II molecules but with higher affinity than CD4. Several alternative mRNA splice-variants of human LAG-3 have been described, two of them encoding potential secreted forms: LAG-3V1 (i.e. the D1-D2 domains of the protein, 36 kDa) and LAG-3V3 (D1-D3, 52 kDa). The longer form was detected by ELISA in the serum of healthy individuals as well as of tuberculosis patients with a favorable outcome. LAG-3 expression by T cell clones correlated with IFN-γ production, and hence soluble LAG-3 has been suggested as a serological marker of Th1 responses.

Catalog Number: 10049-878

Supplier: Enzo Life Sciences

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Description: ß-Nicotinamide adenine dinucleotide phosphate (NADP-Na₂, oxidized form)

Catalog Number: 89151-472

Supplier: Enzo Life Sciences

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Description: A potent substrate analog inhibitor of snake venom PLA2 (IC50=2 µM). It inhibits human recombinant sPLA2 (IC50=0.9 µM) selectively over cPLA2.

Catalog Number: 89164-798

Supplier: Enzo Life Sciences

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Description: The ER-ID® Green assay kit is specifically designed for use with RFP- or OFP-expressing cell lines, as well as cells expressing blue or cyan fluorescent proteins (BFPs, CFPs).

Catalog Number: 89165-914

Supplier: Enzo Life Sciences

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Description: Recommended Applications: Flow Cytometry, IHC (FS)

Species reactivity: Human, Sheep

Catalog Number: 76002-758

Supplier: Enzo Life Sciences

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Description: Isolated from human A431 cells.

Catalog Number: 89163-778

Supplier: Enzo Life Sciences

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Description: Complete kit to digest and label DNA for CGH+SNP arrays.

Catalog Number: 75802-910

Supplier: Enzo Life Sciences

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Description: Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins at the neuromuscular junction during development. Agrin, MuSK, and Rapsyn are all essential components for AChR aggregation, through an unknown mechanism. The C-terminal region of agrin is released into the medium, interacts with receptors on the muscle surface and induces AChR aggregation.

Catalog Number: 200061-662

Supplier: Enzo Life Sciences

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Description: For the quantitative determination of symmetric dimethylarginine (SDMA) in human EDTA-plasma and serum.

Catalog Number: 89156-154

Supplier: Enzo Life Sciences

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Description: The Hsp70 family of heat shock proteins contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

Catalog Number: 95042-194

Supplier: Enzo Life Sciences

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Description: Fluorescein-12-UTP is ideal for in vitro transcription reactions catalyzed by T3, T7, or SP6 RNA polymerases and reverse transcriptase to produce fluorophore-labeled RNA transcripts. RNA-based probes can be used to identify complementary sequences by in situ hybridization to fixed cells and tissues by direct or indirect fluorescence detection or by membrane hybridization procedures.

Catalog Number: 89165-846

Supplier: Enzo Life Sciences

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Description: Fluorogenic substrate for ADAM8 (kcat/Km = 1.0 x 105 M-1s-1), ADAM10 (6.2 x 103), ADAM12 (2.8 x 105), TACE (TNF-α converting enzyme, ADAM17) (4.3 x 105), and likely other ADAMs, especially those that cleave TNF-α type sequences. Also efficiently cleaved by MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, and MMP-14. FAM fluorescence is quenched by the Dabcyl group until cleavage separates them. Ex.: 485nm, Em.: 530nm. This substrate is useful for inhibitor screening and kinetic analysis.

Catalog Number: 89161-126

Supplier: Enzo Life Sciences

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Description: Grp94 (Glucose-regulated protein 94) is an abundant resident endoplasmic reticulum (ER) lumenal stress protein, which together with cytosolic Hsp90 belongs to the Hsp90 family of molecular chaperones. Grp94 expression is upregulated by stress conditions such as glucose starvation and heat shock, which promote protein misfolding or unfolding. In addition to a homeostatic role in protein folding and assembly, Grp94 can function in the intracellular trafficking of peptides from the extracellular space to the MHC class I antigen processing pathway of antigen presentation cells.

Catalog Number: 95042-134

Supplier: Enzo Life Sciences

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Description: Recombinant monclonal antibody (Mouse IgG1κ).

Recommended Applications: Flow Cytometry

Catalog Number: 76284-982

Supplier: Enzo Life Sciences

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Description: Adenylate cyclase inhibitor

Catalog Number: 89157-018

Supplier: Enzo Life Sciences

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