You Searched For: PROSCI INCORPORATED

Catalog Number: (76749-358)

Supplier: Prosci

Description: Anti-CAMK2G Rabbit Polyclonal Antibody

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Catalog Number: (10110-168)

Supplier: Prosci

Description: PRTFDC1 belongs to the purine/pyrimidine phosphoribosyltransferase family. Epigenetic silencing of PRTFDC1 by hypermethylation of the CpG islands leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis.

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Catalog Number: (75794-298)

Supplier: Prosci

Description: Mouse B7-H2, also called CD275, B7RP-1, B7h, LICOS and GL50, is a member of the growing B7 family of immune costimulatory proteins. CD275 has been identified as the ligand for ICOS, a member of the CD28 family of co-stimulatory receptors. Mouse CD275 is expressed on resting B cells and at low levels on monocytes. The CD275/ ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.

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Catalog Number: (76750-914)

Supplier: Prosci

Description: Anti-P2RX3 Rabbit Polyclonal Antibody

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Catalog Number: (76757-972)

Supplier: Prosci

Description: Anti-GRIN2B Rabbit Polyclonal Antibody

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Catalog Number: (10080-630)

Supplier: Prosci

Description: Polyclonal, Host: Rabbit, Species reacivity: human, Immunogen: Synthetic 19 amino acid peptide from internal region of human ENPP3, Tested application: IHC

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Catalog Number: (89417-554)

Supplier: Prosci

Description: ALKBH2 Antibody: The E. coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA; ALKBH2 and ALKBH3 are mammalian homologs of AlkB that catalyze the removal of 1-methyladenine and 3-methylcytosine, modifications that left unchecked could lead to cancerous cells. Mutations in both ALKBH2 and ALKBH3 have been observed in pediatric brain tumors indicating that these proteins are important in the prevention of cancer formation. Like the histone demethylase JMJD1A, ALKBH2 is a non-heme iron enzyme that is inhibited by Nickel ions, suggesting that inhibition of ALKBH2 by Nickel ions may play a role in the development of cancer. Conversely, ALKBH2 mRNA and protein levels are increased glioma cells following Photofrin-mediated photodynamic therapy, an adjuvant therapy in cancer treatment, suggesting that down-regulating ALKBH2 expression in cancer cells may enhance the anti-cancer effectiveness of this treatment.

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Catalog Number: (76629-884)

Supplier: Prosci

Description: Anti-CCR3 Recombinant Antibody [Clone: 5E8-G9-B4]

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Catalog Number: (10107-622)

Supplier: Prosci

Description: PGBD1 belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. This gene product is specifically expressed in the brain, however, its exact function is not known. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. This gene product is specifically expressed in the brain, however, its exact function is not known.

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Supplier: Prosci

Description: Epidermal Growth Factor (EGF) is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-alpha and VGF (vaccinia virus growth factor).

Catalog Number: (75791-162)

Supplier: Prosci

Description: Mouse Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases.Mouse Shh is synthesized as a 437 aa precursor that contains a 24 aa signal sequence and a 413 aa mature region. The mature region is autocatalytically processed into a nonglycosylated, 20 kDa, 174 aa N­terminal fragment (Shh­N), and a catalytic­processing,glycosylated, 34 kDa, 239 aa C­terminal fragment. The 20 kDa Shh­N fragment is the core of the active hedgehog molecule. Mouse Shh­N is 99%, 98%, and 100% aa identical to human, rat and gerbil Shh­N, respectively.

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Catalog Number: (10101-174)

Supplier: Prosci

Description: KCNK10 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is highly expressed in the kidney and pancreas. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. The protein is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Three transcript variants have been identified for this gene.

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Catalog Number: (10102-106)

Supplier: Prosci

Description: This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer.This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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Catalog Number: (77123-500)

Supplier: Prosci

Description: Anti-Cd3e Hamster Monoclonal Antibody [clone: [500-A2]]

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Catalog Number: (10752-006)

Supplier: Prosci

Description: La Crosse Virus Nucleocapsid Antibody: La Crosse virus (LCV) is a single-stranded RNA virus that can cause encephalitis in humans and is transmitted predominantly by mosquitoes. It is often mistaken for herpes simplex encephalitis. During human infections, LCV initially presents as a nonspecific summertime illness with fever, headache, nausea, vomiting and lethargy. Death occurs in less than 1% of clinical cases.

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Catalog Number: (76748-842)

Supplier: Prosci

Description: Anti-IP6K2 Rabbit Polyclonal Antibody

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