You Searched For: PROSCI INCORPORATED

Catalog Number: (76750-854)

Supplier: Prosci

Description: Anti-CNOT1 Rabbit Polyclonal Antibody

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Catalog Number: (10075-106)

Supplier: Prosci

Description: Polyclonal, Host: Rabbit; Species Reactivity: Human; Immunogen: Mouse very low density lipoprotein; Isotype: IgG; Tested Applications: Radial Immunodiffusion Assay, IHC, WB

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Catalog Number: (10113-208)

Supplier: Prosci

Description: Polyclonal, Host: Goat, Species Reactivity: Human, Mouse, Immunogen: AIRE antibody was raised against a 14 amino acid synthetic peptide near the internal region of AIRE, Tested Applications: ELISA, WB

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Catalog Number: (76009-052)

Supplier: Prosci

Description: Isoform CDV-1 may be involved in cardiac hypertrophy caused by carnitine deficiency (By similarity). Isoform CDV-1R appears to play a role in development of the testis and spermatogenesis (By similarity).

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Catalog Number: (10075-384)

Supplier: Prosci

Description: There is accumulating evidence to suggest that progesterone plays an essential role in the regulation of growth and differentiation of mammary glands and thus may play a key role in breast cancer. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (A and B forms). In most cell contexts, the B form functions as a transcriptional activator, whereas the A form functions as a transcriptional inhibitor of steroid hormones. Recently it has been demonstrated that there is differential hormone dependent regulation of the phosphorylation of the A and B forms of the receptor. Treatment of T47D breast cancer cells with progestin agonist increases the phosphorylation of Ser190 and Ser294 with different kinetics. These phosphorylation events may differentially affect the transcriptional activity of the receptor.

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Catalog Number: (76010-170)

Supplier: Prosci

Description: The protein encoded by this gene is specifically expressed in the inner ear, and is located at the interface between the apical surface of the inner ear sensory epithelia and their overlying acellular gels. It is prposed that this protein is involved in the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in this gene are associated with autosomal recessive deafness type 22 (DFNB22). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

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Catalog Number: (10108-096)

Supplier: Prosci

Description: The function remains unknown.

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Catalog Number: (76194-948)

Supplier: Prosci

Description: CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

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Catalog Number: (75794-306)

Supplier: Prosci

Description: Mitochondrial NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Can use tiazofurin monophosphate as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i. e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, mitochondrial NMNAT isoform can use NAD(+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NAADP+. Protects against axonal degeneration following injury.

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Catalog Number: (76009-976)

Supplier: Prosci

Description: May be involved in transcriptional regulation.

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Catalog Number: (77126-460)

Supplier: Prosci

Description: Human Recombinant IL-36 alpha Protein (from <i>E. coli</i>)

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Catalog Number: (77125-440)

Supplier: Prosci

Description: RCBTB2 Peptide

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Catalog Number: (89419-520)

Supplier: Prosci

Description: BRCC36 peptide is used for blocking the activity of BRCC36 antibody.

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Catalog Number: (10764-236)

Supplier: Prosci

Description: The OKT3 monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains gamma, delta, and epsilon chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.

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Catalog Number: (10108-170)

Supplier: Prosci

Description: PRPF6 appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. PRPF6 also can bind androgen receptor, providing a link between transcriptional activation and splicing.The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing.

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Catalog Number: (76012-374)

Supplier: Prosci

Description: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

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