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Catalog Number: (77126-808)

Supplier: Prosci

Description: ADRA1A Peptide

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Catalog Number: (10107-102)

Supplier: Prosci

Description: ZBTB9 contains 1 BTB (POZ) domain and 2 C2H2-type zinc fingers. It may be involved in transcriptional regulation.

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Catalog Number: (76194-192)

Supplier: Prosci

Description: Serum Beta-2 Microglobulin (B2M) levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma.

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Catalog Number: (10749-682)

Supplier: Prosci

Description: Akt1 Antibody: Akt1, initially identified as the cellular homolog to the retro-viral oncogene v-Akt, is part of the phosphatidyl 3'-kinase (PI3K)-Akt signaling pathway that is activated by diverse cellular stimuli and regulates critical cellular functions such as cell growth, proliferation, and survival. Following phosphorylation of the second messenger PIP2 by PI3K, Akt1 translocates to the cell membrane where it is activated by phosphoinositide-dependent kinase (PDK) 1 and PDK2. The active Akt1 is then able to phosphorylate and activate its substrates, including those that are important for cell proliferation and survival such as TOR and the Bcl-2 homolog Bad. Negative regulation of the PI3K-Akt signaling pathway is mainly accomplished by the lipid phosphatase activity of PTEN which catalyzes the conversion of PIP3 to PIP2, thereby preventing the activation of Akt1. Inactivation of this gene often results in excessive Akt1 activity, often leading to the formation of malignant tumors.

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Catalog Number: (76748-656)

Supplier: Prosci

Description: Anti-CACNB2 Rabbit Polyclonal Antibody

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Catalog Number: (10765-852)

Supplier: Prosci

Description: The MAb11 monoclonal antibody specifically reacts with human tumor necrosis factor alpha (TNF-alpha), a 157 amino acid non-glycosylated protein. TNF-alpha is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-alpha is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-alpha also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. The MAB11 antibody was generated from recombinant human TNF and is reported to be a neutralizing antibody.

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Catalog Number: (76764-236)

Supplier: Prosci

Description: Anti-SUCLG1 Rabbit Polyclonal Antibody

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Catalog Number: (89420-446)

Supplier: Prosci

Description: LXR-A peptide is used for blocking the activity of LXR-A antibody.

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Catalog Number: (10114-332)

Supplier: Prosci

Description: Polyclonal, Host: Goat; Immunogen: DYNC1H1 antibody was raised against a 14 amino acid synthetic peptide near the internal region of DYNC1H1; Applications: ELISA

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Catalog Number: (89416-524)

Supplier: Prosci

Description: LGI1 Antibody: The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist, but the top band seen in the western blot is likely to be non-specific. This LGI1 antibody is predicted to be specific to LGI1 and not recognize other LGI proteins.

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Catalog Number: (10751-900)

Supplier: Prosci

Description: RRAS2 Antibody: Activating mutations and overexpression of classical Ras subfamily members (K-RAS, N-RAS and H-RAS) have been widely investigated as key events in the development of human cancers. The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21) and RRAS3 (M-Ras) show overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras and N-Ras) of 55–60%. RRAS2 is a small GTPbinding protein of the Ras superfamily of GTPases. It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins. RRAS2 has high oncogenic potential and overexpression/mutations have been reported in several tumor tissues and cell lines.

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Catalog Number: (76629-250)

Supplier: Prosci

Description: Anti-CD52 Recombinant Antibody [Clone: Campath-1H]

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Catalog Number: (76758-152)

Supplier: Prosci

Description: Anti-BRF2 Rabbit Polyclonal Antibody

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Catalog Number: (76760-518)

Supplier: Prosci

Description: Anti-Cnr1 Rabbit Monoclonal Antibody [clone: E5 ]

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Catalog Number: (77134-538)

Supplier: Prosci

Description: Anti-NP Mouse Monoclonal Antibody [clone: [3D7]]

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Catalog Number: (10109-572)

Supplier: Prosci

Description: Related to nucleologenesis, NOLC1 may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. NOLC1 may play an important role in transcription catalyzed by RNA polymerase I.

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