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Description: Anti-Sheep Igg (Handl) (Rabbit) Antibody Dylight* 488 Conjugated (5 X 100Ug) - 613441-002-0.5 Sheep Igg (Handl) Antibody Dylight* 488 Conjugated 500Ug

Catalog Number: RL6134410020.5

Supplier: Rockland Immunochemical

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Description: 10X Tris-Borate-EDTA (TBE) (0.9 M Tris-Borate, 0.01 M EDTA, pH 8.3)

Catalog Number: RLMB-019

Supplier: Rockland Immunochemical

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Description: Suitable for highly specific immunological methods requiring extremely low background levels, absence of F(c) mediated binding, lot-to-lot consistency, high titer and specificity.

Catalog Number: RL809-1102

Supplier: Rockland Immunochemical

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Description: PIWI-L2 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. PIWI-L2 has been implicated in multiple roles including stem cell self-renewal and is highly expressed in many breast cancers. In these tumors, PIWI-L2 silences the expression of STAT3, a regulator of Bcl-XL and cyclin D1, allowing the proliferation and survival of breast cancer stem cells. Recent studies have shown that overexpression of PIWI-like proteins are potential biomarkers for colon and other cancers.

Catalog Number: 75931-032

Supplier: Rockland Immunochemical

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Description: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59L is a type I membrane glycoprotein that is expressed in the brain. A related protein, TMEM59, is a Golgi-localized protein that modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP and inhibits APP transport and shedding.

Catalog Number: 75932-976

Supplier: Rockland Immunochemical

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Description: Secondary Goat Anti-IgG (H&L) Reacts with Guinea Pig

Catalog Number: RL606-102-129

Supplier: Rockland Immunochemical

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Description: Secondary Goat Anti-IgM Reacts with Mouse

Catalog Number: RL110-1107

Supplier: Rockland Immunochemical

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Description: Anti-VlsE antibody has been tested in ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band at ~36.3 kDa in size corresponding to VlsE by Western blotting in the appropriate cell lysate or extract.

Catalog Number: RL200-401-C33S

Supplier: Rockland Immunochemical

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Description: SOX17 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate (1,2). SOX17 is part of the SoxF subgroup which plays an important role in the differentiation of different cell types, including visceral and definitive endoderm and hematopoietic cell types (3,4). SOX17 is also essential for acquisition and maintenance of arterial identity (5).

Catalog Number: 75932-118

Supplier: Rockland Immunochemical

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Description: USP10, also known as ubiquitin specific peptidase 10, belongs to the ubiquitin-specific protease family of cysteine proteases. USP10 functions to catalyze the cleavage of ubiquitin from ubiquitin-conjugated protein substrates such as p53/TP53, SNX3 and CFTR. USP10 has been identified as a subunit of DNA-bound androgen receptor (AR) complexes and may play a role in the activity of the DNA-bound androgen receptor complex. USP10 also acts as an essential regulator of p53/TP53 stability and is thought to function as a tumor suppressor.

Catalog Number: 75933-456

Supplier: Rockland Immunochemical

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Description: It Is Suitable For Use In WB And ELISA. Expect A Band Approximately 78Kda Corresponding To Specific Lysates. Specific Conditions For Reactivity Should Be Optimized By The End User.

Catalog Number: RL200-301-F37

Supplier: Rockland Immunochemical

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Description: The emission spectra for this ATTO conjugate matches the principle output wavelengths of most common fluorescence instrumentation.

Catalog Number: RL605-453-013

Supplier: Rockland Immunochemical

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Description: STREPTAVIDIN ATTO 550 Conjugated

Catalog Number: RLS00054

Supplier: Rockland Immunochemical

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Description: Periphilin, known as PPHLN1 or gastric cancer antigen Ga50, plays a role in epithelial differentiation and contributes to epidermal integrity and barrier formation. It interacts with periplakin, a known precursor of the cornified cell envelope. Periphilin 1 is ubiquitously expressed and localizes to nucleus and cytoplasm. Existing as eight alternatively spliced isoforms, Periphilin is highly insoluble and contains a putative nuclear localization signal (NLS) within its N-terminal half, a prerequisite for the formation of insoluble complexes and a possible caspase recognition sequence and a potential nuclear export signal. Periphilin may play an important role in the nervous system.

Catalog Number: 75930-794

Supplier: Rockland Immunochemical

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Description: rHuman Fractalkine (CX3CL1) control protein

Catalog Number: 10801-480

Supplier: Rockland Immunochemical

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Description: Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFa, LPS and mitogens. A serine/threonine protein kinase which mediates NF-kB activation by IL-1, TNFa and CD95 was identified recently and designated NIK (for NF-kB inducing kinase). NIK is an activator of IkB kinase alpha and beta (IKKa and IKKb). Therefore, NIK is a key molecule in the NF-kB signaling pathway leading to the induction of a variety of gene expression in response to proinflammatory cytokines and bacteria products.

Catalog Number: 75930-438

Supplier: Rockland Immunochemical

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