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Catalog Number: (RL600-401-E49)
Supplier: Rockland Immunochemical
Description: Anti-Tryptophan Hydroxylase pS260 (Rabbit) antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of 55 kDa in size corresponding to typtophan hydroxylase Protein phosphorylated at Ser 260.


Catalog Number: (RL712-1031)
Supplier: Rockland Immunochemical
Description: Secondary Goat Anti-F(ab')2 Reacts with Rat

SDS


Catalog Number: (76262-856)
Supplier: Rockland Immunochemical
Description: ERK1 antibodies detect the ERK1 isoform. Mitogen activiated protein kinase 3, also known as MAPK3, ERK, or ERK1, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. ERK1 and ERK2 are activated by MEK1 and MEK2 in the B-raf signaling pathway resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Human ERK1 and ERK2 are 84% identical in sequence and share common functionality in cells. Anti-ERK1 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.


Catalog Number: (RL200-B02-N92)
Supplier: Rockland Immunochemical
Description: Anti-TCRbeta is useful for Immunofluorescence, Immunoprecipitation, and Flow Cytometry using mouse spleen cells, or an appropriate cell type (where indicated). Researchers should determine optimal titers for applications that are not stated.


Catalog Number: (RL712-400-002)
Supplier: Rockland Immunochemical
Description: Secondary Rabbit Anti-IgG (H&L) Reacts with Rat


Catalog Number: (RL201032300100)
Supplier: Rockland Immunochemical
Description: Polyclonal antibody, Host:Goat, Species reactivity:Escherichia coli, Label:Peroxidase (Horseradish), Immunogen:Maltose Phosphorylase [E.coli], Application:ELISA, Western Blot, ImmunoPrecipitation


Catalog Number: (RL600-401-B16)
Supplier: Rockland Immunochemical
Description: Anti-TRIM29 Rabbit Polyclonal Antibody


Catalog Number: (76262-846)
Supplier: Rockland Immunochemical
Description: MEK1 antibodies detect the MEK1 isoform. Mitogen-activated protein kinase kinase 1, also known as MKK or MEK, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. This pathway also plays a key role in synaptic plasticity in the brain. Activated MEK 1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase. The MEK1 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.


Catalog Number: (RL600-401-A69)
Supplier: Rockland Immunochemical
Description: Anti-TLR9 Rabbit Polyclonal Antibody


Catalog Number: (RL200406141S)
Supplier: Rockland Immunochemical
Description: Anti-Beta-2-Microglobulin (Human Urine) (Rabbit) Antibody Biotin Conjugated Is Suitable For Western Blotting To Detect A Single Band Of The Expected Apparent Molecular Weight And For ELISA.


Catalog Number: (76262-862)
Supplier: Rockland Immunochemical
Description: ERK1 antibodies detect the ERK1 isoform. Mitogen activiated protein kinase 3, also known as MAPK3, ERK, or ERK1, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. ERK1 and ERK2 are activated by MEK1 and MEK2 in the B-raf signaling pathway resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Human ERK1 and ERK2 are 84% identical in sequence and share common functionality in cells. Anti-ERK1 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.


Catalog Number: (76234-980)
Supplier: Rockland Immunochemical
Description: HbA antibodies detect the hemoglobin beta subunit wild type variant A isoform. Functional adult hemoglobin (Hb) is a hetero tetramer composed of 2 alpha and 2 beta subunits (α2β2). Common isoform variants of hemoglobin include HbA, HbS, HbC, HbF, and HbA-2. Sickle cell disease (SCD), thalassemias and hemoglobinopathies occur when aberrant forms of hemoglobin are expressed in children and adults. Globin gene mutations affect the structure and expression levels of Hb. Sickle cell disease and the more benign sickle cell trait are observed in more than 100 million people globally. Perhaps the most significant mutation is the E6V in the beta subunit and the cause of SCD, but other relevant isoforms of Hb are observed. HbA antibody cross reacts with HbA-2 but does not react other forms Hb. This antibody is ideal for investigators involved in Cardiovascular and developmental biology research.


Catalog Number: (76234-822)
Supplier: Rockland Immunochemical
Description: Leptin is a key player in the regulation of energy balance and body weight control. Once released into the circulation, it has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. It acts as an appetite-regulating factor, regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones, it increases basal metabolism, influences reproductive function, regulates pancreatic beta-cell function and insulin secretion, it induces FOS and SOCS3 expression to release anorexigenic peptides. It has a modulatory role in nutrient absorption. It reduces glucose absorption by enterocytes by activating PKC and leading to a sequential activation of p38, PI3K and ERK signaling pathways which exerts an inhibitory effect on glucose absorption. It acts as a growth factor on certain tissues, through the activation of different signaling pathways increases expression of genes involved in cell cycle regulation such as CCND1, via JAK2-STAT3 pathway, or VEGFA, via MAPK1/3 and PI3K-AKT1 pathways. It may also play an apoptotic role via JAK2-STAT3 pathway and up-regulation of BIRC5 expression. It plays a pro-inflammatory role, in synergy with IL1B, by inducing NOS2 which promotes the production of IL6, IL8 and Prostaglandin E2, through a signaling pathway that involves JAK2, PI3K, MAP2K1/MEK1 and MAPK14/p38. In adaptive immunity, promotes the switch of memory T-cells towards T helper-1 cell immune responses. Increases CD4+CD25- T cells proliferation and reduces autophagy during TCR (T cell receptor) stimulation, through MTOR signaling pathway activation and BCL2 up-regulation.


Catalog Number: (RL600-401-D87)
Supplier: Rockland Immunochemical
Description: Anti-NMDA R1, Splice Variant C2' (Rabbit) Antibody is suitable for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 120 kDa in size corresponding to the NMDA receptor.


Catalog Number: (10802-446)
Supplier: Rockland Immunochemical
Description: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. A mouse DNase that causes DNA fragmentation was identified recently and designated CAD for caspase activated deoxyribonuclease. The human homologue of mouse CAD was more recently identified by three groups independently and termed CPAN, DFF40, and human CAD, respectively. DFF45/ICAD is the inhibitory protein of DFF40/CAD and forms complex with DFF40/CAD. Upon cleavage of DFF45/ICAD by activated caspase, DFF40/CAD is released and activated and eventually causes the degradation of DNA in the nuclei. Activation of DFF40/CAD, which causes DNA degradation, is the hallmark of apoptotic cell death.


Supplier: Rockland Immunochemical
Description: Revitablot™ Western Blot Stripping Buffer

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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