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Catalog Number: (10801-518)
Supplier: Rockland Immunochemical
Description: GAB1 pY659 antibody detects phosphorylated GAB1. GAB1 is a member of the IRS1-like multisubstrate docking protein family. The protein is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. GAB1 plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. It is known to play a role in FGFR1 signaling and is probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). GAB1 interacts with GRB2 and with other SH2-containing proteins. It is known to interact with phosphorylated LAT2, PTPRJ, FRS2, GRB2, PIK3R1 and SOS1. GAB1 gets phosphorylated in response to FGFR1 activation. This tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains. Anti-GAB1 Antibody is ideal for investigators involved in Cell Signaling, Cancer, Neuroscience and Signal Transduction research.


Supplier: Rockland Immunochemical
Description: Suspensions are suitable for complement fixation, hemagglutination, hemadsorption, and other related serological procedures

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Catalog Number: (10799-582)
Supplier: Rockland Immunochemical
Description: The actin filament-associated protein AFAP1 (AFAP-110) is an actin cross-linking protein first identified as a substrate of the viral oncogene v-Src. AFAP1 has a fundamental role in actin cytoskeleton arrangement. It contains a carboxyterminal actin-binding domain that directly binds to F-actin and serves as an adaptor protein in the regulation of SRC and PKC signal transduction by several functional domains, including 2 pleckstrin homology (PH) domains, a Src homology 3-binding (SH3-binding) motif, and several SH2-binding motifs. It is overexpressed in prostate carcinoma and contributes to tumor growth by regulating cell-matrix adhesions and migration in the cancer cells. AFAP1 represent a possible therapeutic target for controlling tumorigenesis and metastasis.


Catalog Number: (10801-132)
Supplier: Rockland Immunochemical
Description: The Drosha-DGCR8 microprocessor complex is required for microRNA (miRNA) biogenesis. DGCR8 (DiGeorge Syndrome Critical Region 8) recognizes the RNA substrate, whereas Drosha functions as the endonuclease. DGCR8, which contains two double-stranded RNA (dsRNA)-binding domains, interacts with the pri-miRNA and functions as the molecular anchor that measures the distance from the ds-RNA-ssRNA junction and directs Drosha cleavage 11bp away. The efficiency of Drosha cleavage increases in the presence of heme and promotes the formation of highly ordered DGCR8 structures upon binding to RNA. DGCR8 pS377 Antibody is ideal for researchers interested in neuroscience research.


Catalog Number: (10802-050)
Supplier: Rockland Immunochemical
Description: Beclin-1 plays a key role in tumor suppression and autophagy. It has been suggested that autophagy proteins such as beclin-1 can inhibit tumorigenesis and that decreased expression of these proteins may contribute to the development of human malignancies. Beclin-1 has been shown to interact with 14-3-3 proteins through Akt-mediated phosphorylation at Ser234. Beclin 1 pS234 Antibody is ideal for researchers interested in cancer research.


Catalog Number: (75930-222)
Supplier: Rockland Immunochemical
Description: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP13 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP13, it has been suggested that it may be implicated in the activation of proinflammatory caspases via inflammasomes.


Supplier: Rockland Immunochemical
Description: Sterile Plasma in Anticoagulant

Catalog Number: (75932-074)
Supplier: Rockland Immunochemical
Description: SNCB control protein-HIS Epitope


Supplier: Rockland Immunochemical
Description: LACTATE DEHYDROGENASE antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 36 kDa in size.

Catalog Number: (RL600-401-412)
Supplier: Rockland Immunochemical
Description: This affinity purified polyclonal antibody was tested by ELISA and immunoblotting and was found to be reactive with 48 kDa mouse and Rat caspase-2.


Supplier: Rockland Immunochemical
Description: Anti-Dopamine beta-Hydroxylase Antibody is suitable for use in ELISA and Western Blotting. Specific conditions for reactivity should be optmized by the end user. Expect a band of approximately 75 kDa in size corresponding to DBH Protein.

Catalog Number: (10800-968)
Supplier: Rockland Immunochemical
Description: The CXCR3 protein is a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-gamma), CXCL10/IP10 (interferon-gamma-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell alpha-chemoattractant) (reviewed in 1). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration (2). Similar to other chemokine receptors such as CXCR4, CXCR3 has been implicated in several malignancies as a biomarker of tumor behavior as well as a potential therapeutic target (3).


Catalog Number: (RL200-401-A67)
Supplier: Rockland Immunochemical
Description: Anti-TIRAP Rabbit Polyclonal Antibody


Catalog Number: (76222-530)
Supplier: Rockland Immunochemical
Description: MEK1 C-Term Blocking Control Peptide


Catalog Number: (RL100-401-A17)
Supplier: Rockland Immunochemical
Description: This antibody reacts with human CDC20 (fizzy) by western blot and immunoprecipitation.  The antibody immunoprecipitates in vitro translated Protein and Protein from overexpressing cell lysates (using HeLa and NIH-3T3, and others).


Supplier: Rockland Immunochemical
Description: TrueBlot® Biotin Magnetic Beads

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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