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Catalog Number: (103264-782)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Human IgG antibody with minimal reactivity to rhesus and cynomolgus proteins for use in ELISA and immunoprecipitation assays.


Catalog Number: (100242-224)
Supplier: Southern Biotechnology
Description: PE ApoScreen® Annexin V Apoptosis Kit for use in flow cytometry assays.


Catalog Number: (100242-964)
Supplier: Southern Biotechnology
Description: Biotin Anti-Type I Collagen antibody for use in ELISA, immunohistochemistry / immunocytochemistry, electron microscopy, flow cytometry, western blotting, and immunoprecipitation assays.


Catalog Number: (103264-352)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgM-Alexa Fluor 647 antibody with minimal reactivity to human proteins for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100242-796)
Supplier: Southern Biotechnology
Description: FITC Anti-Mouse IgM antibody for use in flow cytometry, immunohistochemistry, and western blotting assays.


Catalog Number: (103265-082)
Supplier: Southern Biotechnology
Description: Donkey Anti-Goat IgG(H+L)-Biotin antibody with minimal reactivity to human, mouse, rat, hamster, rabbit, chicken, horse, and guinea pig serum proteins for use in ELISA, western blotting, and immunohistochemistry assays.


Catalog Number: (103265-376)
Supplier: Southern Biotechnology
Description: The BC96 monoclonal antibody reacts with human CD25, the 55 kDa interleukin-2 receptor α chain (IL-2Rα). CD25 is expressed by early progenitors of T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor β chain) and CD132 (common γ chain) to form the high affinity IL-2 receptor. CD25 plays a role in lymphocyte differentiating and activation/proliferation. CD25 is expressed on activated B cells, monocytes/macrophages, and T cells.


Catalog Number: (101442-748)
Supplier: Southern Biotechnology
Description: CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow.


Catalog Number: (103265-272)
Supplier: Southern Biotechnology
Description: CD56, an isoform of the neural cell adhesion molecule (NCAM), is a heavily glycosylated type I transmembrane protein. On human hematopoietic cells its expression is restricted to NK cells and a subpopulation of T lymphocytes (known as large granular lymphocytes) which demonstrate natural killer activity. While it is clear that NCAM plays a role in homotypic adhesion of neuronal cells, the significance of CD56 expression on NK cells is not clear and remains controversial.


Catalog Number: (100243-026)
Supplier: Southern Biotechnology
Description: CD106, also known as VCAM-1, is an adhesion molecule and a major mediator of the inflammatory response. It is expressed on activated microvascular endothelial cells in response to signals arising from immune responses in infection, graft rejection, tumor recognition and killing. The complementary binding ligand for VCAM-1 is VLA-4/CD49d. In addition to VCAM-1, VLA-4 also recognizes the extracellular matrix molecule fibronectin. This pairing of VCAM-1 and VLA-4 is able to provide a second signal (e.g., non-antigen specific) for T cell stimulation, such as that seen in transplantation. The monoclonal antibody MK-2 has been used in transplant studies to suppress cardiac rejection and induce long-term cardiac graft survival. In addition to inflammatory responses, VCAM-1 has a significant role in hemopoiesis through its ability to retain lymphocyte and myeloid precursors on stromal cells in the marrow and lymphoid organs. CD106/VCAM-1 exists as an integral membrane protein. The M/K-2 monoclonal antibody immunoprecipitates a peptide that gives a single band on SDS-PAGE gels with an apparent Mr of ~100 kDa under reducing conditions and 92 kDa under non-reducing conditions.


Catalog Number: (100242-474)
Supplier: Southern Biotechnology
Description: Biotin Anti-Mouse IFN-gamma antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, ELISA, ELISpot, and multiplex assays.


Catalog Number: (103265-484)
Supplier: Southern Biotechnology
Description: FITC Anti-Mouse IL-2 antibody for use in flow cytometry and immunohistochemistry assays.


Catalog Number: (103259-878)
Supplier: Southern Biotechnology
Description: FITC Anti-Type I Collagen antibody for use in immunohistochemistry / immunocytochemistry, flow cytometry, and western blotting assays.


Catalog Number: (103265-538)
Supplier: Southern Biotechnology
Description: Glial fibrillary acid protein (GFAP) is a member of the type III intermediate filament family of proteins. GFAP is heavily expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and functions of the cell’s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cell; however, its precise function remains poorly understood. In adults, GFAP levels increase in response to the proliferation of astrocytes associated with Alzheimer’s disease, epilepsy, and multiple sclerosis. Antibodies specific for GFAP are useful as markers of astrocytic cells and neural stem cells as well as for distinguishing neoplasms of astrocytic origin from other neoplasms in the central nervous system.


Supplier: Southern Biotechnology
Description: CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107a is expressed by activated T cells, macrophages, dendritic cells, activated platelets, tonsillar epithelium, and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential where they may increase adhesion to extracellular matrix and endothelium.

Catalog Number: (103264-974)
Supplier: Southern Biotechnology
Description: Purified Rabbit Anti-Sheep IgG(H+L) antibody with minimal reactivity to human serum proteins for use in ELISA, immunohistochemistry, and western blotting assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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