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Catalog Number: (100243-914)
Supplier: Southern Biotechnology
Description: CD103 is a member of the integrin series of adhesion molecules. This antigen defines a developmentally important subset of T cells, namely mucosal T cells including all IEL (intraepithelial lymphocytes) and ~20% of lamina propria T cells. Expression of CD103 is more restricted outside these mucosal organs appearing at lower levels on T cell subsets of the lymph node, dendritic epidermis, and periphery. In non-epithelial CD103+ T cells there is a bias toward expression on CD8+ cells. The 2E7 monoclonal antibody exhibits antigen immunoprecipitation patterns similar if not identical to the rat anti-mouse CD103 monoclonal antibody M290. 2E7 is reported to have signal-inducing activity in a redirected lysis assay and to costimulate IEL and CD8+ lymph node cells in conjunction with anti-TCR in vitro which runs counter to the usual inhibition of CTL by anti-integrins. This costimulatory activity is also shared by the monoclonal antibody M290. The property of costimulation is not unique to the mouse since the combination of anti-human αIEL plus anti-TCR will produce similar proliferation in human cells with the exception that CD8+ cells are not stimulated.


Catalog Number: (100245-990)
Supplier: Southern Biotechnology
Description: CD56, an isoform of the neural cell adhesion molecule (NCAM), is a heavily glycosylated type I transmembrane protein. On human hematopoietic cells its expression is restricted to NK cells and a subpopulation of T lymphocytes (known as large granular lymphocytes) which demonstrate natural killer activity. While it is clear that NCAM plays a role in homotypic adhesion of neuronal cells, the significance of CD56 expression on NK cells is not clear and remains controversial.


Catalog Number: (103264-814)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Rat IgG-HRP antibody for use in ELISA assays.


Catalog Number: (103265-342)
Supplier: Southern Biotechnology
Description: CD16, a member of the immunoglobulin superfamily, is a 50-65 kDa glycoprotein found as both a transmembrane and GPI-linked form. The transmembrane form of CD16 is expressed on NK cells, granulocytes, macrophages, and mast cells but not on eosinophils. The GPI-anchored type of CD16 is found only on neutrophils. CD16 is involved in NK activation and signal transduction.


Catalog Number: (100242-106)
Supplier: Southern Biotechnology
Description: Rat IgG2b-PE for use as a control in flow cytometry assays.


Catalog Number: (100244-844)
Supplier: Southern Biotechnology
Description: Porcine CD4 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. CD4 is an accessory molecule in the recognition of foreign antigens in association with MHC Class II molecules by T lymphocytes.


Catalog Number: (100246-038)
Supplier: Southern Biotechnology
Description: CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3 is expressed on 70-80% of normal peripheral blood lymphocytes and on 10-20% of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation. The monoclonal antibody UCHT1 reacts with the 20 kDa ε chain of the CD3/TCR complex.


Catalog Number: (103264-888)
Supplier: Southern Biotechnology
Description: Goat Anti-Rabbit IgG(H+L)-Alexa Fluor 488 antibody with minimal reactivity to mouse and human proteins for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100245-224)
Supplier: Southern Biotechnology
Description: Purified Rabbit Anti-Hamster IgG(H+L) antibody with minimal reactivity to mouse proteins for use in ELISA and flow cytometry assays.


Catalog Number: (103264-732)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgG(H+L)-Biotin antibody with minimal reactivity to mouse, bovine, and horse serum proteins for use in ELISA assays.


Catalog Number: (101442-518)
Supplier: Southern Biotechnology
Description: Mouse IgA-APC/CY5.5 for use as a control in flow cytometry assays.


Catalog Number: (100246-542)
Supplier: Southern Biotechnology
Description: CD26, also known as dipeptidyl peptidase (DPP IV), is a 110 kDa type II integral membrane glycoprotein that is primarily expressed by CD3+ medullary thymocytes and peripheral T cells. CD26 is serine protease that is also associated with T cell activation and proliferation, cell to cell adhesion, and HIV infection.


Catalog Number: (103264-870)
Supplier: Southern Biotechnology
Description: Goat Anti-Rabbit IgG Fab-HRP antibody for use in ELISA assays.


Catalog Number: (103265-292)
Supplier: Southern Biotechnology
Description: CD11b is the 165 kDa αM chain which combines with the CD18 β2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2).


Catalog Number: (103265-036)
Supplier: Southern Biotechnology
Description: Donkey Anti-Mouse IgG(H+L)-Alexa Fluor 488 antibody for use in fluorescent assays.


Catalog Number: (100244-256)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Human IgD-Biotin antibody for use in ELISA, flow cytometry, immunohistochemistry, and separation assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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