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Description: CD45, also known as the leukocyte common antigen (LCA), exists as four different isoforms (180, 190, 205, 220 kDa) that are generated by alternative splicing of three exons. LCA is found on all cells of hematopoietic origin, except erythrocytes and platelets. CD45 expression is required for T cell and B cell antigen receptor-mediated activation.
Catalog Number: 103265-402
Supplier: Southern Biotechnology


Description: Purified Goat F(ab')2 Anti-Mouse IgG(H+L) antibody with minimal reactivity to human proteins for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.
Catalog Number: 100242-520
Supplier: Southern Biotechnology


Description: Biotin Anti-Human IgG Fc antibody for use in ELISA, flow cytometry, immunohistochemistry, western blotting, and multiplex assays.
Catalog Number: 100245-688
Supplier: Southern Biotechnology


Description: FITC Anti-Rat Kappa antibody for use in flow cytometry, ELISA, immunohistochemistry, and western blotting assays.
Catalog Number: 100244-640
Supplier: Southern Biotechnology


Description: Goat Anti-Mouse IgA-TRITC antibody for use in immunohistochemistry / immunocytochemistry assays.
Catalog Number: 100242-560
Supplier: Southern Biotechnology


Description: FITC Anti-Human Kappa antibody for use in flow cytometry assays.
Catalog Number: 103265-234
Supplier: Southern Biotechnology


Description: CD43, a member of the sialomucin family of cell surface receptors, is a 95-135 kDa type I transmembrane glycoprotein whose variability in molecular weight is dependent upon the nature of the extracellular O-glycans. It is the major sialoglycoprotein on thymocytes, T cells, and neutrophils. It is also present on activated B cells, plasma cells, NK cells, granulocytes, monocytes, macrophages, platelets, and bone marrow hematopoietic stem cells. CD43, which binds to ICAM-1 (CD54), appears to function as an anti-adhesion molecule, inhibiting T cell interactions including T cell killing, and by increasing the threshold for T cell activation.
Catalog Number: 100246-268
Supplier: Southern Biotechnology


Description: CD5, a member of the scavenger receptor superfamily of cell surface receptors, is a type I transmembrane glycoprotein whose ligand is CD72. It is expressed on most thymocytes, all mature T cells, and a subset of B cells. CD5 plays a role in regulation of T cell activation and signaling.
Catalog Number: 103260-198
Supplier: Southern Biotechnology


Description: Rabbit F(ab')2 Anti-Rat IgG(H+L)-AP antibody with minimal reactivity to human proteins for use in ELISA and immunocytochemistry assays.
Catalog Number: 100245-094
Supplier: Southern Biotechnology


Description: The monoclonal antibody DX5 reacts with CD49b, also known as very late antigen-2 (VLA-2) and α2 integrin. The antibody stains the majority of NK cells and a small subpopulation of T cells in all mouse strains tested (e.g., A/J, AKR, BALB/c, C3H/HeJ, C57BL/6, C57BL/10, C57BR, C58, CBA/Ca, CBA/J, DBA/1, DBA/2, SJL, SWR). Three-color flow cytometry analysis has revealed that most cells that express NK-1.1 (NKR-P1C) also express CD49b. However, small subsets of DX5+NK-1.1- and DX5-NK-1.1+ cells can be found, especially among the CD3+ population of T lymphocytes. NK cells cultured in the presence of IL-2 progressively lose reactivity with DX5 as a consequence of cellular proliferation. Therefore, DX5 can be used to define functionally distinct subsets of murine NK cells. The monoclonal antibody DX5 has not been demonstrated to have activating or blocking activity.
Catalog Number: 100243-878
Supplier: Southern Biotechnology


Description: CD4 is a type I transmembrane glycoprotein expressed on approximately 70% of thymocytes, 10% of spleen cells, and 45% of peripheral blood lymphocytes but less than 1% of bursal cells.
Catalog Number: 100245-460
Supplier: Southern Biotechnology


Description: Mouse IgG-PE/CY5 (SPRD) for use as a control in flow cytometry assays.
Catalog Number: 100241-996
Supplier: Southern Biotechnology


Description: CD22, also known as Lyb-8, is a heterodimeric transmembrane glycoprotein and a member of a structurally related group of immunoglobulin (Ig) superfamily domain-containing proteins called the sialoadhesin family. It is detected in the cytoplasm early in B cell development (late pro-B cell stage), appears on the cell surface concomitant with IgD, and is found on most IgM+IgD+ mature B lymphocytes. Expression is lost with terminal differentiation of B cells and is absent on plasma cells. Activation of B cells via cross-linking of surface Ig increases CD22 expression. CD22 associates with the B cell receptor (BCR) complex and mediates intercellular adhesion. Its intracellular domain is phosphorylated after antigen receptor cross-linking and is involved in negative regulation of B cell activation.
Catalog Number: 100243-302
Supplier: Southern Biotechnology


Description: CD69, also known as very early activation (VEA) antigen, is a disulfide-linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa. It is a C-type lectin most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. CD69 is widely expressed on hematopoietic cells, including lymphocytes, neutrophils and eosinophils. Although not detectable on resting lymphocytes, its expression is rapidly upregulated upon activation of T, B and NK cells, and neutrophils. Constitutive expression of CD69 on subsets of thymocytes suggests that it may be involved in regulation of developmental events in addition to its role in activation of a variety of hematopoietic cells. The monoclonal antibody H1.2F3 augments PMA-induced T-cell proliferation and induces redirected lysis of Fc receptor-bearing target cells by NK cells.
Catalog Number: 103259-938
Supplier: Southern Biotechnology


Description: CD19 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is expressed at all stages of B cell differentiation except terminally differentiated plasma cells. It is also present on the cell surface of follicular dendritic cells. CD19 associates with CD21, CD81, Leu 13 and/or MHC Class II molecules to form a signal transduction complex on the B cell surface. This signaling complex modulates the activation threshold for the B cell antigen receptor (BCR).
Catalog Number: 103265-702
Supplier: Southern Biotechnology


Description: Low Endotoxin/Azide Free Anti-Mouse IL-10 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, ELISA, ELISpot, neutralization assays.
Catalog Number: 101190-232
Supplier: Southern Biotechnology


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