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Description: Mouse IgG2a-PE/CY7 for use as a control in flow cytometry assays.
Catalog Number: 100241-930
Supplier: Southern Biotechnology


Description: CD9 is a 24 kDa member of the transmembrane 4 superfamily (TM4-SF) of cell surface receptors. It is expressed strongly on platelets, lymphoid progenitor cells, activated lymphocytes and endothelia, and, weakly, on eosinophils, granulocytes, monocytes, and macrophages. CD9 functions as an adhesion molecule where it mediates platelet aggregation and activation.
Catalog Number: 100245-870
Supplier: Southern Biotechnology


Description: CD45, also known as the leukocyte common antigen (LCA), exists as four different isoforms (180, 190, 205, 220 kDa) that are generated by alternative splicing of three exons. LCA is found on all cells of hematopoietic origin, except erythrocytes and platelets. CD45 expression is required for T cell and B cell antigen receptor-mediated activation.
Catalog Number: 103265-398
Supplier: Southern Biotechnology


Description: Laminins, a family of extracellular matrix glycoproteins, are a major component of basement membranes consisting of an α-chain, a β-chain, and a γ-chain. Laminins have been implicated in a numerous biological activities including cell migration, adhesion, and differentiation.
Catalog Number: 100243-002
Supplier: Southern Biotechnology


Description: Donkey Anti-Mouse IgG(H+L)-Alexa Fluor 647 antibody with minimal reactivity to human, goat, sheep, bovine, rabbit, chicken, horse, and guinea pig serum proteins for use in immunocytochemistry assays.
Catalog Number: 103265-066
Supplier: Southern Biotechnology


Description: The monoclonal antibody 2F1 reacts with mouse killer cell lectin-like receptor G1 (KLRG1; formerly known as mouse MAFA), a homodimeric member of the lectin-like type 2 transmembrane receptor family that contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1. The 2F1 antibody stains 30-60% of NK1.1+CD3- splenocytes, and a small fraction of T cells in all mouse strains tested (C57BL/6, BALB/c, 129/J, C3H.SW, AKR/J, SJL). Cell surface expression of KLRG1 is up-regulated by expression of MHC class I molecules. The effect of MHC class I expression is indirect, and can be mediated by interactions with class I-specific Ly49 inhibitory receptors.
Catalog Number: 100243-890
Supplier: Southern Biotechnology


Description: AP Anti-Rabbit Light Chain antibody for use in ELISA and western blotting assays.
Catalog Number: 103260-052
Supplier: Southern Biotechnology


Description: Rabbit F(ab')2 Anti-Mouse IgG(H+L)-HRP antibody for use in ELISA and immunocytochemistry assays.
Catalog Number: 100245-070
Supplier: Southern Biotechnology


Description: Purified Donkey F(ab')2 Anti-Mouse IgG(H+L) antibody for use in ELISA assays.
Catalog Number: 103265-042
Supplier: Southern Biotechnology


Description: Purified Rat IgG2a for use as a control in flow cytometry, immunohistochemistry, immunoprecipitation, and in vitro assays and as a standard in ELISA.
Catalog Number: 100242-082
Supplier: Southern Biotechnology


Description: Ly-6C is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T-cell subsets. Mice with the Ly-6.2 allotype (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have subsets of CD4+Ly-6C+ and CD8+Ly-6C+ cells while Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+Ly-6C+ lymphocytes. Ly-6C may play a role in the development and maturation of lymphocytes.
Catalog Number: 103264-618
Supplier: Southern Biotechnology


Description: Purified Goat F(ab’)2 IgG for use as a control in flow cytometry and immunocytochemistry assays and as a standard in ELISA.
Catalog Number: 100242-028
Supplier: Southern Biotechnology


Description: The CD35 antigen is composed of four different allotypes having different molecular weights [A (or F) - 160 kDa, B (or S) - 190 kDa, C - 220 kDa, and D - 250 kDa]. It is the receptor for C3b and is found on B cells, a subset of T cells, monocytes, neutrophils, follicular dendritic cells, erythrocytes, and kidney glomelular podocytes. CD35 mediates neutrophil and monocyte phagocytosis of particles coated with C3b and/or C4b. This interaction also enhances phagocytosis mediated by the Fc receptors.
Catalog Number: 100246-232
Supplier: Southern Biotechnology


Description: In the mouse, CD8 exists in two forms – (i) a CD8 heterodimer composed of an α chain (CD8α) and a β chain (CD8β); and (ii) a homodimer of two α chains. The heterodimer is found on the surface of essentially all thymocytes and the “suppressor/cytotoxic” subpopulation of mature T lymphocytes. Subsets of intestinal intraepithelial lymphocytes express CD8α without CD8β. It has been suggested that CD8+β- T cells mature extrathymically, while development of the CD8α+β+ population of T cells is thymus-dependent. CD8 acts as a coreceptor with MHC Class I-restricted T cell receptors in antigen recognition and positive selection of MHC class I-restricted CD8+ T cells. In vivo and in vitro treatment with the 53-6.7 monoclonal antibody effectively depletes CD8α+ cells. The 53-6.7 monoclonal antibody also blocks allogeneic help specific for class I MHC antigens and T cell responses to IL-2.
Catalog Number: 100243-176
Supplier: Southern Biotechnology


Description: CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P-selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes.
Catalog Number: 100243-332
Supplier: Southern Biotechnology


Description: Goat F(ab')2 Anti-Mouse IgG(H+L)-PE/CY5 (SPRD) antibody with minimal reactivity to human proteins for use in flow cytometry assays.
Catalog Number: 100242-534
Supplier: Southern Biotechnology


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