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Catalog Number: (100242-228)
Supplier: Southern Biotechnology
Description: Bcl-xL is a 29 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. It is found in both soluble and membrane fractions of cellular lysates. Like Bcl-2, Bcl-xL has been demonstrated to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. While formation of heterodimers with the apoptosis-enhancing protein, Bax does not block the apoptosis-suppressing property of Bcl-xL, heterodimerization with Bad effectively inhibits the protective function of Bcl-xL.


Catalog Number: (100245-930)
Supplier: Southern Biotechnology
Description: CD20 is a 33-37 kDa unglycosylated phosphoprotein. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. It is expressed on all stages of B cell differentiation except plasma cells. The CD20 molecule is involved in regulation of B cell differentiation presumably via its reported function as a Ca++ channel subunit.


Catalog Number: (103259-658)
Supplier: Southern Biotechnology
Description: Interleukin-25 (IL-25), also known as interleukin-17E (IL-17E), is a 17 kDa protein and member of the IL-17 cytokine family. This cytokine is secreted by a variety of cells including type 2 helper T cells (Th2), bone marrow-derived mast cells, and alveolar macrophages. On target cells, IL-25 can induce the production of several type 2 cytokines including IL-4, IL-5, and IL-13 and implicates a role for this cytokine in type 2 immune response. Studies have linked this cytokine in promoting airway hyperreactivity, limiting pro-inflammatory cytokine production and chronic intestinal inflammation, and providing protective immunity following intestinal helminth infection.


Catalog Number: (100244-766)
Supplier: Southern Biotechnology
Description: Goat Anti-Rabbit IgG(H+L)-FITC antibody with minimal reactivity to mouse and human proteins for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100241-956)
Supplier: Southern Biotechnology
Description: Mouse IgG3-Biotin for use as a control in flow cytometry and immunocytochemistry assays.


Catalog Number: (103264-762)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Human IgD-Alexa Fluor 488 antibody for use in flow cytometry and immunohistochemistry assays.


Catalog Number: (100242-506)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG(H+L)-Texas Red antibody with minimal reactivity to human proteins for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (103264-484)
Supplier: Southern Biotechnology
Description: Alexa Fluor 555 Anti-Mouse IgM antibody for use in immunohistochemistry and western blotting assays.


Catalog Number: (100245-168)
Supplier: Southern Biotechnology
Description: Rabbit Anti-Mouse IgG(H+L)-HRP antibody for use in ELISA, immunohistochemistry, western blotting, and ELISpot assays.


Catalog Number: (103264-778)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgG Fc-Alexa Fluor 647 antibody for use in western blotting and for other fluorescent assays.


Catalog Number: (100245-052)
Supplier: Southern Biotechnology
Description: Goat Anti-Chicken IgY(H+L)-AP antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (103265-480)
Supplier: Southern Biotechnology
Description: Low Endotoxin/Azide Free Anti-Human IL-5 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, ELISA, ELISpot, and neutralization assays.


Supplier: Southern Biotechnology
Description: Gelatin Subbed Slides are subbed with a solution of 0.1% gelatin and chromium potassium sulfate.

Catalog Number: (100245-082)
Supplier: Southern Biotechnology
Description: Rabbit F(ab')2 Anti-Rat IgG(H+L)-FITC antibody for use in immunohistochemistry / immunocytochemistry and western blotting assays.


Catalog Number: (101442-832)
Supplier: Southern Biotechnology
Description: CY5 Anti-Rat IgG2b antibody for use in flow cytometry, immunohistochemistry, and western blotting assays.


Catalog Number: (100243-310)
Supplier: Southern Biotechnology
Description: The CD23 antigen is the low affinity IgE Fc receptor, which is a 45-49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells) and can also be found on the surface of T cells, macrophages and platelets. It is distinct from the high affinity IgE receptors found on basophils and mast cells which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system which involves interactions of cells, cytokines, antibodies and regulatory factors. CD23 has been described as a “membrane bound cytokine," in that the soluble cleavage products of CD23 are themselves able to act as cytokines in vitro.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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