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Catalog Number: (103264-206)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Mouse Ig-Alexa Fluor 488 antibody with minimal reactivity to human proteins for use in flow cytometry, immunocytochemistry, and western blotting assays.


Catalog Number: (103264-962)
Supplier: Southern Biotechnology
Description: Goat Anti-Chicken IgY(H+L)-FITC antibody with minimal reactivity to human, mouse, rat, bovine, horse, hamster, goat, sheep, rabbit, and guinea pig serum proteins for use in fluorescent assays.


Catalog Number: (100243-126)
Supplier: Southern Biotechnology
Description: CD4 is a type I transmembrane glycoprotein expressed on most thymocytes and the helper/inducer subpopulation of mature T lymphocytes of all mouse strains tested. CD4 has also been detected at low density on pluripotent hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic lymphoid precursors. The CD4 antigen functions as a co-receptor, interacting with class II major histocompatability complex (MHC) molecules in the recognition of foreign antigens by T cells. In vivo and in vitro treatment with the GK1.5 monoclonal antibody effectively depletes CD4+ cells. GK1.5 also blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.


Catalog Number: (100245-128)
Supplier: Southern Biotechnology
Description: Rabbit Anti-Sheep IgG(H+L)-Biotin antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (103264-704)
Supplier: Southern Biotechnology
Description: Goat Anti-Human Ig-Alexa Fluor 555 antibody for use in immunocytochemistry and western blotting assays.


Catalog Number: (100243-098)
Supplier: Southern Biotechnology
Description: CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The monoclonal antibody C363.29B recognizes an epitope on the 25 kDa ε chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble C363.29B can activate primed and naïve T cell in vitro. Immobilized C363.2B9 monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. The monoclonal antibody is cytolytic, easily used for cell surface staining, and a good immunoprecipitating antibody.


Catalog Number: (103259-706)
Supplier: Southern Biotechnology
Description: Rat IgG2b-HRP for use as a control in immunohistochemistry assays.


Catalog Number: (103265-602)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG1-Alexa Fluor 488 antibody for use in immunocytochemistry and fluorescent assays.


Catalog Number: (100245-768)
Supplier: Southern Biotechnology
Description: FITC Anti-Human IgA2 antibody for use in flow cytometry, immunohistochemistry, and western blotting assays.


Catalog Number: (103265-444)
Supplier: Southern Biotechnology
Description: CD158e1 is a 70 kDa transmembrane glycoprotein and a killer cell immunoglobulin (Ig)-like receptor (KIR) that is expressed on a subset of natural killer cells and T cells. The monoclonal antibody DX9 is expressed on a subset of CD3-, CD56+ NK cells isolated from peripheral blood at varying levels (<0.1% to 61%) among individuals but not on thymocytes, B lymphocytes, granulocytes, or monocytes. Interactions with CD158e1 and certain MHC HLA-B antigens on a target cell inhibits cytotoxicity, possibly preventing target cell lysis and death. KIR and MHC class I interactions may regulate NK and T cell response to antigen stimulation.


Catalog Number: (100242-966)
Supplier: Southern Biotechnology
Description: Purified Anti-Type II Collagen antibody for use in ELISA, immunohistochemistry / immunocytochemistry, electron microscopy, western blotting, and immunoprecipitation assays.


Catalog Number: (100243-388)
Supplier: Southern Biotechnology
Description: CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80 (B7-1) and CD86 (B7-2) on B cells and other antigen presenting cells and plays an important role in the interaction between T cells and B cells. CD28 is a costimulatory receptor involved in many, but not all, T-cell independent immune responses.


Catalog Number: (100243-352)
Supplier: Southern Biotechnology
Description: The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity α chain of the IL-2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O-linked carbohydrates and has a short cytoplasmic tail. CD25 is expressed on activated T cells, B cells, NK cells, and monocytes of all mouse strains tested. It is transiently expressed at a low level during B cell development in bone marrow on the CD45R/B220low TdT- sIg- pre-B II and CD45R/B220low TdT- sIgM+sIgD- immature B cells, but not on the CD45R/B220low TdT+ sIg- pro-B/pre-B I stage nor on CD45R/B220high TdT- sIgM+sIgD+ mature B cells. CD25 is expressed at a higher level during very early T-cell development in fetal and adult thymus. The 7D4 monoclonal antibody reacts with an epitope between amino acids 125 and 212 that is distinct from that recognized by the monoclonal antibody 3C7 (SB Cat. No. 1600). While the monoclonal antibody 7D4 does not block the binding of IL-2 to CD25, when used in combination with the monoclonal antibody 3C7 it results in higher levels of inhibition of IL-2-driven proliferation than either of these two monoclonal antibodies alone.


Catalog Number: (101442-590)
Supplier: Southern Biotechnology
Description: Low Endotoxin/Azide Free Anti-Human IL-10 antibody for use in flow cytometry, immunohistochemistry, ELISA, ELISpot, western blotting, multiplex, and neutralization assays.


Catalog Number: (103265-332)
Supplier: Southern Biotechnology
Description: CD14 is a 55 kDa glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells, and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.


Catalog Number: (100244-910)
Supplier: Southern Biotechnology
Description: Purified Rabbit F(ab')2 Anti-Human IgG(H+L) antibody for use in ELISA, immunocytochemistry, and western blotting assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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