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Description: Purified Goat Anti-Mouse IgE antibody for use in ELISA, flow cytometry, immunocytochemistry, western blotting, and immunoprecipitation assays.
Catalog Number: 100242-762
Supplier: Southern Biotechnology


Description: CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The 145-2C11 monoclonal antibody recognizes an epitope on the 25 kDa ε chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble 145-2C11 can activate primed and naïve T cell in vitro. 145-2C11 can also induce redirected lysis of specific target cells by CTL clones and it can block lysis of specific target cells by antigen-specific CTL’s. Immobilized 145-2C11 can activate both normal T lymphocytes and cloned T cell lines. Under certain conditions, T cell activation by 145-2C11 may result in apoptotic cell death.
Catalog Number: 100243-072
Supplier: Southern Biotechnology


Description: Low Endotoxin/Azide Free Mouse F(ab’)2 IgG1 for use as a control in flow cytometry, immunohistochemistry, and in vitro assays and as a standard in ELISA.
Catalog Number: 100242-064
Supplier: Southern Biotechnology


Description: Goat F(ab’)2 Anti-Mouse IgM-Alexa Fluor 555 antibody with minimal reactivity to human proteins for use in immunohistochemistry / immunocytochemistry assays.
Catalog Number: 103264-368
Supplier: Southern Biotechnology


Description: Purified Anti-Human IgG2 Fc antibody for use in ELISA, flow cytometry, immunocytochemistry, western blotting, ELISpot, and multiplex assays.
Catalog Number: 100245-722
Supplier: Southern Biotechnology


Description: Goat Anti-Human Lambda-Alexa Fluor 488 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
Catalog Number: 103260-012
Supplier: Southern Biotechnology


Description: CD1 molecules, like MHC I and II, play an important role in the immune system by presenting lipid, glycolipid and lipopeptide antigen to T and NKT cells. The chicken CD1 gene is located in the chicken MHC B locus and has an important implication for the primordial MHC gene evolution. Two proteins have been identified - CD1.1 and CD1.2. Analysis of RNA from blood cells showed that both genes are expressed in Bu-1+ cells and CD8α+ cells. CD1.2 is expressed in TCRγδ cells but is nearly undetectable in TCRαβ. The monoclonal antibody CB3 antibody can identify cells of the B cell lineage and recognizes CD1.1 but not CD1.2 on the surface of transfected mammalian cells.
Catalog Number: 103265-154
Supplier: Southern Biotechnology


Description: CD11a, also known as leukocyte function-associated antigen-1 (LFA-1α), represents the 180 kDa integrin αL subunit which combines with the CD18 β2 integrin subunit to form the αLβ2 integrin heterodimer. It is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T cells. CD11a mediates adhesion of lymphocytes to vascular endothelium and is involved in costimulation.
Catalog Number: 101442-904
Supplier: Southern Biotechnology


Description: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). The two keratin types share only 30% sequence homology. Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 8 belongs to the type B (basic) subfamily of keratins and exists in combination with keratin 18. It is expressed in all simple type epithelia tissues (e.g., liver, pancreas, kidney, gut epithelial lining) but not in stratified squamous epithelia. Cytokeratin 8 is also present in the majority of adenocarcinomas and ductal carcinomas but is absent in most squamous cell carcinomas.
Catalog Number: 103265-464
Supplier: Southern Biotechnology


Description: Goat Anti-Hamster IgG(H+L)-Biotin antibody for use in ELISA, western blotting, and separation assays.
Catalog Number: 100244-996
Supplier: Southern Biotechnology


Description: Goat Anti-Hamster IgG(H+L)-HRP antibody with minimal reactivity to mouse and rat proteins for use in ELISA, immunohistochemistry, and western blotting assays.
Catalog Number: 100245-004
Supplier: Southern Biotechnology


Description: Goat Anti-Rat Ig-AP antibody with minimal reactivity to mouse proteins for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.
Catalog Number: 100244-414
Supplier: Southern Biotechnology


Description: Rat IgG2b-PE/CY7 for use as a control in flow cytometry assays.
Catalog Number: 100242-116
Supplier: Southern Biotechnology


Description: CD40 is a type I cell surface protein belonging to the tumor necrosis factor superfamily of cell surface receptors. In mice it is expressed on B lineage cells, follicular dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zone of secondary lymphoid organs. CD40 first becomes detectable on a subset of small pre-B II cells in bone marrow with the levels of CD40 expression increasing thereafter during B cell maturation. Immature B cells (IgM+IgDloB220lo) express intermediate levels of CD40, whereas mature B cells (IgM+IgDhiB220hi) express high levels. CD40 has a central role in B cell growth and differentiation, and signaling through CD40 in combination with IL-4 reportedly induces immunoglobulin isotype switching and secretion of IgE. The agonistic 1C10 antibody closely resembles gp39/CD40 ligand in its ability to stimulate proliferation of small, resting B lymphocytes in the absence of other cofactors.
Catalog Number: 100243-482
Supplier: Southern Biotechnology


Description: CD14 is a 55 kDa glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells, and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.
Catalog Number: 100246-154
Supplier: Southern Biotechnology


Description: CD45RC represents an exon C-dependent isoform of CD45 glycoprotein. It is expressed at high density on all B lymphocytes, at intermediate density on most CD8+ splenic T cells, and on two subpopulations of CD4+ splenic T cells with high and low density of expression. CD45RC is also present on a small subset of thymocytes.
Catalog Number: 100243-940
Supplier: Southern Biotechnology


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