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Catalog Number: (103264-602)
Supplier: Southern Biotechnology
Description: CD90 (Thy-1) is a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily consisting of a single V-set domain. The Thy-1.2 alloantigen is expressed on all thymocytes, peripheral T lymphocytes, and some intraepithelial T cells of most mouse strains. It is also expressed in the brain and at varying levels on other non-lymphoid tissues. The 30-H12 monoclonal antibody does not cross react with mouse and rat strains bearing the Thy-1.1 alloantigen (e.g., AKR/J, PL).


Catalog Number: (103264-340)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Mouse IgG Fc antibody with minimal reactivity to human, bovine, and horse serum proteins for use in ELISA assays.


Catalog Number: (103264-490)
Supplier: Southern Biotechnology
Description: FITC Anti-Mouse IgG1 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100242-994)
Supplier: Southern Biotechnology
Description: Protein tyrosine residues are phosphorylated as a result of intracellular protein kinase activation (e.g., via growth factors) during normal growth and development and in oncogenesis. The most abundant population of target proteins for tyrosine phosphorylation is cell surface glycoproteins. Antibodies to phosphotyrosine enable the detection, isolation, and characterization of proteins containing phosphotyrosine. The monoclonal antibody PY20 prevents internalization of activated receptors (e.g., EGFR) when microinjected into cells. The affinity of PY20 for phosphotyrosine is approximately 10-6 to 10-7 M. PY20 binding to phosphorylated tyrosines can be inhibited by free phosphotyrosine and phenylphosphate but not by phosphoserine, phosphothreonine, or free phosphate.


Catalog Number: (100243-464)
Supplier: Southern Biotechnology
Description: Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCRαβ+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B and T cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.


Catalog Number: (100245-184)
Supplier: Southern Biotechnology
Description: Rabbit Anti-Rat IgG(H+L)-FITC antibody for use in immunohistochemistry and western blotting assays.


Catalog Number: (100245-384)
Supplier: Southern Biotechnology
Description: Feline CD5, a member of the scavenger receptor family of cell surface receptors, is a type I transmembrane glycoprotein that is expressed on most thymocytes and mature T lymphocytes. CD5 is thought to function in both cell-cell recognition and signal transduction. The monoclonal antibody f43 is useful as a pan T cell marker.


Catalog Number: (100244-792)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Rabbit IgG(H+L)-AP antibody with minimal reactivity to mouse and human proteins for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100241-986)
Supplier: Southern Biotechnology
Description: Mouse IgG-FITC for use as a control in flow cytometry and immunohistochemistry / immunocytochemistry assays.


Catalog Number: (103260-054)
Supplier: Southern Biotechnology
Description: HRP Anti-Rabbit Light Chain antibody for use in ELISA and western blotting assays.


Catalog Number: (103265-590)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG1-Alexa Fluor 555 antibody with minimal reactivity to human proteins for use in immunohistochemistry / immunocytochemistry and western blotting assays.


Catalog Number: (100245-092)
Supplier: Southern Biotechnology
Description: Rabbit F(ab')2 Anti-Rat IgG(H+L)-FITC antibody with minimal reactivity to human proteins for use in flow cytometry and immunocytochemistry assays.


Catalog Number: (100243-402)
Supplier: Southern Biotechnology
Description: CD30 is a type I transmembrane protein and a member of the tumor necrosis factor receptor superfamily of proteins. Murine CD30 is expressed predominantly in the thymus and it is inducible in mouse splenocytes stimulated with pokeweed mitogen or concanavalin A. In anti-CD3ε-activated spleen cells, CD30 is expressed primarily on the surface of CD8+ T cells with peak expression on days 4 and 5. Stimulation of CD30+ CTL lines with plate-bound anti-CD30 directly signals IL-5 but not IFN-γ production. While these studies demonstrate that CD30 directs cytokine secretion and suggest that CD30 may play a pivotal role in the pattern of cytokine production by T cells, the precise roles of CD30 and its ligand (CD153) in T-cell development have not been clearly defined.


Catalog Number: (100242-338)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Mouse Ig-CY5 antibody with minimal reactivity to human proteins for use in flow cytometry, immunocytochemistry, and western blotting assays.


Catalog Number: (103264-868)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Rabbit IgG Fab antibody for use in ELISA assays.


Catalog Number: (103264-850)
Supplier: Southern Biotechnology
Description: Alexa Fluor 488 Anti-Rat IgM antibody for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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