You Searched For: AMERICAN RADIOLABELED CHEM MS


3,038  results were found

Sort Results

List View Easy View (new)
SearchResultCount:"3038"
Description: CD45, also known as the leukocyte common antigen (LCA), exists as four different isoforms (180, 190, 205, 220 kDa) that are generated by alternative splicing of three exons. LCA is found on all cells of hematopoietic origin, except erythrocytes and platelets. CD45 expression is required for T cell and B cell antigen receptor-mediated activation.
Catalog Number: 103265-398
Supplier: Southern Biotechnology


Description: Laminins, a family of extracellular matrix glycoproteins, are a major component of basement membranes consisting of an α-chain, a β-chain, and a γ-chain. Laminins have been implicated in a numerous biological activities including cell migration, adhesion, and differentiation.
Catalog Number: 100243-002
Supplier: Southern Biotechnology


Description: HRP Anti-Mouse Lambda antibody for use in ELISA, immunohistochemistry, and western blotting assays.
Catalog Number: 100242-874
Supplier: Southern Biotechnology


Description: Purified Anti-Human IL-7 antibody for use in ELISA and immunocytochemistry assays.
Catalog Number: 100242-342
Supplier: Southern Biotechnology


Description: Hamster IgG-PE/CY5 (SPRD) for use as a control in flow cytometry assays.
Catalog Number: 100242-144
Supplier: Southern Biotechnology


Description: CD62L, also known as L-selectin, is a type I transmembrane glycoprotein with lectin-like and epidermal growth factor-like domains. It binds to sialylated oligosaccharide determinants on high endothelial venules (HEV) in peripheral lymph nodes. In the mouse, CD62L is expressed on most thymocytes and on peripheral leukocytes, including B and T lymphocytes, neutrophils, monocytes, and eosinophils. This member of the selectin family of cell adhesion molecules appears to be required for lymphocyte homing to peripheral lymph nodes and for leukocyte extravasation at sites of inflammation. Expression of CD62L on lymphocytes and neutrophils is rapidly down-regulated upon cell activation and the level of CD62L expression, along with other markers, distinguishes naive T cells from effector/memory T cells. The monoclonal antibody MEL-14 blocks in vitro binding of lymphocytes to peripheral lymph node HEV and inhibits in vivo lymphocyte extravasation into peripheral lymph nodes and the late stages of leukocyte rolling.
Catalog Number: 103259-932
Supplier: Southern Biotechnology


Description: The αβ TCR is expressed on T lymphocytes of all mouse strains tested. The H57-597 monoclonal antibody does not react with γδ TCR-bearing cells. Plate-bound or soluble H57-597 activates αβ TCR-bearing T cells. In vitro and in vivo, H57-597 can induce immature thymocytes to undergo apoptosis. In vivo administration of H57-597 has been shown to deplete αβ TCR-bearing cells to near completion and prevent graft rejection.
Catalog Number: 103264-626
Supplier: Southern Biotechnology


Description: The monoclonal antibody TCR-3 precipitates a CD3-associated heterodimer of Mr 88 kDa (two bands of Mr 48 kDa and 40 kDa upon reduction) on chicken peripheral blood T cells. Deglycosylation of the heterodimer yields two polypeptides of Mr 34 kDa and 31 kDa. In the chicken, two distinct subpopulations of αβ T cells appear in the thymus subsequent to the appearance of γδ T cells. These subpopulations, originally denoted as TCR-2 and TCR-3, arise sequentially in the thymus during ontogeny and are now known to represent two distinct Vβ families, Vβ1 and Vβ2, respectively. The TCR-3 monoclonal antibody reacts with approximately 9% of thymocytes, 15-25% of blood mononuclear cells, and 13% of splenocytes young adult chickens. Two-color immunofluorescence has revealed that the TCR-3+ thymocytes include CD4+CD8-, CD4-CD8+, CD4+CD8+, and CD4-CD8- subpopulations. The TCR-3+ thymocytes can be separated into two subsets. One subset is characterized by relatively low levels of expression of the TCR-3/CD3 complex and most of the cells in this subset are CD4+CD8+. Cells in the other subset express TCR-3/CD3 in higher density and are either CD4+CD8- or CD4-CD8+, corresponding to the more mature medullary subset of thymocytes. The TCR-3+] cells in the blood and spleen express relatively high levels of the TCR-3/CD3 receptor complex and are “single positive” with CD4+CD8- cells being four times more frequent that the CD4-CD8+ cells (~ 80% CD4+ vs ~ 20% CD8+).
Catalog Number: 100245-456
Supplier: Southern Biotechnology


Description: Ly-6C is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T-cell subsets. Mice with the Ly-6.2 allotype (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have subsets of CD4+Ly-6C+ and CD8+Ly-6C+ cells while Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+Ly-6C+ lymphocytes. Ly-6C may play a role in the development and maturation of lymphocytes.
Catalog Number: 103264-618
Supplier: Southern Biotechnology


Description: Murine CD79 is a disulfide-linked heterodimer composed of an α chain (CD79a) and a β chain (CD79b) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation.
Catalog Number: 100243-958
Supplier: Southern Biotechnology


Description: AP Anti-Rabbit Light Chain antibody for use in ELISA and western blotting assays.
Catalog Number: 103260-052
Supplier: Southern Biotechnology


Description: Purified Donkey F(ab')2 Anti-Mouse IgG(H+L) antibody for use in ELISA assays.
Catalog Number: 103265-042
Supplier: Southern Biotechnology


Description: Rat IgG2a-PE/Texas Red for use as a control in flow cytometry assays.
Catalog Number: 101442-542
Supplier: Southern Biotechnology


Description: Low Endotoxin/Azide Free Anti-Mouse IL-3 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, ELISA, ELISpot, multiplex, and neutralization assays.
Catalog Number: 101190-234
Supplier: Southern Biotechnology


Description: Goat F(ab’)2 Anti-Mouse IgG1-Alexa Fluor 647 antibody with minimal reactivity to human proteins for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.
Catalog Number: 103265-610
Supplier: Southern Biotechnology


Description: Goat Anti-Mouse IgG2a-APC antibody with minimal reactivity to human proteins for use in flow cytometry assays.
Catalog Number: 100242-692
Supplier: Southern Biotechnology