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Image Unavailable-100243-818

Anti-CD45.2 Mouse Monoclonal Antibody (Spectral Red® RPE (R-Phycoerythrin)/Cy5®) [clone: 104]

Catalog Number: (100243-818)
Supplier: Southern Biotechnology
Description: The CD45 antigen is an essential regulator of leukocyte activation and development and is now known to be a protein tyrosine phosphatase, e.g., CD45 is able to dephosporylate the Src family of protein kinases. This activity is known to be required for signal transduction induced by T and B cell antigen receptor engagement, cytokine signaling, and Fc receptor stimulation. The functional state of CD45 also has a pronounced effect on lymphocyte development. CD45 exists in multiple forms, such as the restricted variants (CD45R; see companion products 1660, 1665, 1675, 1685 and 1820) and as allelic forms CD45.1 (Ly-5.1) and CD45.2 (Ly-5.2). The specificity of antibodies to CD45.1 and CD45.2 has been exploited in studies where resolution of donor and recipient cells is essential, such as in gene therapy or bone marrow transplantation. The monoclonal antibody 104 recognizes CD45 (leukocyte common antigen) on all leukocytes of mouse strains expressing the CD45.2 allotype (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129).
Image Unavailable-100244-126

Anti-H-2Dk Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: 15-5-5]

Catalog Number: (100244-126)
Supplier: Southern Biotechnology
Description: The monoclonal antibody 15-5-5 reacts with the H-2Dk class I alloantigen. It cross-reacts with H-2Kd and with cells from mice with the H-2f haplotype. The antibody does not react with other (e.g., a, b, p, q, r, s) haplotypes.
Image Unavailable-100242-546

Anti-IgG (H+L) Goat Antibody (AP (Alkaline Phosphatase))

Catalog Number: (100242-546)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG(H+L)-AP antibody with minimal reactivity to rat proteins for use in ELISA, immunohistochemistry / immunocytochemistry, ELISpot, and western blotting assays.
Image Unavailable-100244-366

Anti-Kappa Goat Antibody (Biotin)

Catalog Number: (100244-366)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Human Kappa-Biotin antibody with minimal reactivity to mouse proteins for use in ELISA, flow cytometry, ELISpot, and stimulation assays.
Image Unavailable-103265-076

Anti-IgG (H+L) Donkey Antibody

Catalog Number: (103265-076)
Supplier: Southern Biotechnology
Description: Purified Donkey F(ab')2 Anti-Goat IgG(H+L) antibody with minimal reactivity to mouse and rat serum proteins for use in ELISA assays.
Image Unavailable-100242-376

Anti-IgM Goat Antibody (Biotin)

Catalog Number: (100242-376)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgM-Biotin antibody with minimal reactivity to human proteins for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, electron microscopy, western blotting, immunoprecipitation, and ELISpot assays.
Image Unavailable-100244-946

Anti-IgG (H+L) Rabbit Antibody (AP (Alkaline Phosphatase))

Catalog Number: (100244-946)
Supplier: Southern Biotechnology
Description: Rabbit F(ab')2 Anti-Goat IgG(H+L)-AP antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.
Image Unavailable-103264-524

Anti-CD2 Rat Monoclonal Antibody [clone: 43449]

Catalog Number: (103264-524)
Supplier: Southern Biotechnology
Description: CD2, also known as leukocyte function-associated antigen-2 (LFA-2), is a member of the immunoglobulin superfamily of cell adhesion molecules. It is expressed on the surface of >95% of thymocytes, and essentially all B cells, T cells and NK cells. In the mouse, CD2 is the receptor for CD48. CD2 is thought to play a major role in mediating T-cell adhesion, T-cell recognition/activation, T-cell signaling, and intrathymic differentiation.
Image Unavailable-101442-952

Anti-CD13 Mouse Monoclonal Antibody [clone: 22A5]

Catalog Number: (101442-952)
Supplier: Southern Biotechnology
Description: CD13, also known as aminopeptidase N, is a 150 kDa type II integral membrane glycoprotein. It is expressed on granulocytes, monocytes and their precursors, and on mast cells. CD13 is a zinc-binding metalloprotease that is involved in cell surface antigen presentation via its digestion of many MHC-bound regulatory peptides.
Image Unavailable-103259-856

Anti-IgG2b Rat Antibody (HRP (Horseradish Peroxidase)) [clone: SB74g]

Catalog Number: (103259-856)
Supplier: Southern Biotechnology
Description: HRP Anti-Mouse IgG2b antibody for use in ELISA, immunocytochemistry, and western blotting assays.
Image Unavailable-100245-682

Anti-IgG F(c) Mouse Antibody [clone: JDC-10]

Catalog Number: (100245-682)
Supplier: Southern Biotechnology
Description: Purified Anti-Human IgG Fc antibody for use in ELISA, flow cytometry, immunohistochemistry, western blotting, and multiplex assays.
Image Unavailable-100244-120

Anti-H-2Db Mouse Monoclonal Antibody (RPE (R-Phycoerythrin)) [clone: 27-11-13S]

Catalog Number: (100244-120)
Supplier: Southern Biotechnology
Description: The monoclonal antibody 27-11-13S recognizes with the α3 domain of H-2Db class I MHC antigen. The antibody cross-reacts with the α3 domain of H-2Dd, H-2Dq, H-2Ld and H-2Lq but not H-2Kb. Reactivity with haplotypes k, f, p, r, and s has not been observed.
Image Unavailable-100245-206

Anti-IgG (H+L) Goat Antibody (TRITC (Tetramethylrhodamine Isothiocyanate))

Catalog Number: (100245-206)
Supplier: Southern Biotechnology
Description: Goat Anti-Rhesus IgG(H+L)-TRITC antibody for use in immunocytochemistry assays.
Image Unavailable-103264-478

Anti-IgM Rat Antibody [clone: SB73a]

Catalog Number: (103264-478)
Supplier: Southern Biotechnology
Description: Purified Anti-Mouse IgM antibody for use in ELISA, flow cytometry, immunohistochemistry, and western blotting assays.
Image Unavailable-100243-904

Anti-CD94 Rat Monoclonal Antibody (RPE (R-Phycoerythrin)) [clone: 18d3]

Catalog Number: (100243-904)
Supplier: Southern Biotechnology
Description: The monoclonal antibody 18d3 reacts with the mouse CD94 receptor subunit, a type II transmembrane glycoprotein. CD94 is expressed on the surface of NK cells, NK T cells, and some memory phenotype CD8+ cells. When CD94 is paired with NKG2A, C, or E subunit, it binds the nonclassical MHC class Ib molecule Qa-1b and results in a CD94high population by flow cytometry. Approximately half of NK cells do not express NKG2A, C or E; these cells express CD94 on the surface in a form that does not bind Qa-1b and is believed to be nonfunctional, producing a CD94low population by flow cytometry. CD94 is thought to play a role in the adhesion and activation of the NK cell lineage.
Image Unavailable-100243-962

Anti-CD104 Rat Monoclonal Antibody [clone: 346-11A]

Catalog Number: (100243-962)
Supplier: Southern Biotechnology
Description: CD104 represents the integrin β4 subunit that associates non-covalently with integrin α6 (CD49f) to form the α6β4 integrin heterodimer. The α6β4 complex is expressed on the basal surface of a variety of epithelial cell types particularly on stratified squamous epithelia. It is also found in peripheral nerves, in certain subsets of endothelial cells, and on immature thymocytes. It also has been found to be associated with a number of malignant tissues. Hemidesmosomal α6β4 plays an important role in the adhesion of epithelial cells to basement membranes via interactions with laminin and/or kalinin anchoring filaments. It is not known if the monoclonal antibody 346-11A can block this adhesion.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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