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Catalog Number: (100243-256)
Supplier: Southern Biotechnology
Description: CD18 represents the common β2 integrin subunit that associates non-covalently with the α/β chains of CD11a, CD11b, and CD11c to form various integrin heterodimers. It is expressed strongly on lymphocytes and monocytes and weakly on granulocytes. CD18 mediates a variety of heterotypic and homotypic intercellular adhesion reactions and it regulates the ligand-binding activates of the various CD11/CD18 complexes. The monoclonal antibody C71/16 has not been reported to inhibit cell adhesion.


Catalog Number: (100243-034)
Supplier: Southern Biotechnology
Description: VLA-4 belongs to the β1-integrin family, which functions both as cell-matrix and cell-cell receptors. As a matrix receptor VLA-4 binds to an alternatively spliced domain of fibronectin, while as a cellular receptor it associates with its counter-receptor ligand VCAM-1. In addition to CD44/Pgp-1, VLA-4 has been shown to be important for lymphopoiesis, and is also believed to be important for extravasation of lymphocytes into sites of inflammation as a second signal in addition to LFA/ICAM-1. CD49d is expressed in low amounts on resting lymphocytes and monocytes, is absent or minimally detectable on stromal cells, whereas virtually all lymphoid and myeloid cells in bone marrow and in long-term culture are positive. Antibody PS/2 also reacts with human VLA-4.


Catalog Number: (101442-868)
Supplier: Southern Biotechnology
Description: Goat Anti-Chicken IgY(H+L)-PE antibody for use in flow cytometry assays.


Catalog Number: (103259-926)
Supplier: Southern Biotechnology
Description: CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes, and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN γ, IL-1, TNF-α, lipopolysaccharide, and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1.


Catalog Number: (100245-788)
Supplier: Southern Biotechnology
Description: FITC Anti-Human Lambda antibody for use in flow cytometry and western blotting assays.


Catalog Number: (100244-556)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Rat IgG antibody with minimal reactivity to mouse and human proteins for use in ELISA and flow cytometry assays.


Catalog Number: (100241-896)
Supplier: Southern Biotechnology
Description: Mouse IgG1-Biotin for use as a control in flow cytometry, immunohistochemistry / immunocytochemistry, and multiplex assays.


Catalog Number: (100244-750)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Rabbit IgG antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100245-400)
Supplier: Southern Biotechnology
Description: Feline CD4, a member of the immunoglobulin superfamily of cell surface receptors, is a type I transmembrane glycoprotein that is expressed on the helper/inducer subpopulation of peripheral T lymphocytes. It is present on approximately 55% of thymocytes, 15% of splenocytes, 40% of lymph node cells, and 25% of peripheral blood lymphocytes. CD4 functions as an accessory molecule in the recognition of foreign antigens in association with MHC Class II antigens by T cells.


Catalog Number: (103259-722)
Supplier: Southern Biotechnology
Description: Rat IgG2c-Biotin for use as a control in flow cytometry assays.


Catalog Number: (100246-068)
Supplier: Southern Biotechnology
Description: CD5, a member of the scavenger receptor superfamily of cell surface receptors, is a type I transmembrane glycoprotein whose ligand is CD72. It is expressed on most thymocytes, all mature T cells, and a subset of B cells. CD5 plays a role in regulation of T cell activation and signaling.


Supplier: Southern Biotechnology
Description: CD19 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is expressed at all stages of B cell differentiation except terminally differentiated plasma cells. It is also present on the cell surface of follicular dendritic cells. CD19 associates with CD21, CD81, Leu 13 and/or MHC Class II molecules to form a signal transduction complex on the B cell surface. This signaling complex modulates the activation threshold for the B cell antigen receptor (BCR).

Catalog Number: (103264-790)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgG-Alexa Fluor 647 antibody with minimal reactivity to rhesus and cynomolgus proteins for use in fluorescent assays.


Catalog Number: (100241-878)
Supplier: Southern Biotechnology
Description: Mouse IgM-FITC for use as a control in flow cytometry and immunohistochemistry assays.


Catalog Number: (103265-118)
Supplier: Southern Biotechnology
Description: Donkey Anti-Goat IgG Fc-HRP antibody for use in ELISA assays.


Catalog Number: (100245-412)
Supplier: Southern Biotechnology
Description: CD3 is a member of the T cell receptor-associated CD3 complex. The monoclonal antibody CT-3 recognizes a complex of at least three polypeptides of Mr 20, 19, and 17 kDa (two of which are N-glycosylated) on chicken T cells. The antibody also coprecipitates a polypeptide of 90 kDa from digitonin solubilized T cell lysates, which can be reduced to two polypeptides of Mr 50 and 40 kDa.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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