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Catalog Number: (103264-976)
Supplier: Southern Biotechnology
Description: Rabbit Anti-Sheep IgG(H+L)-FITC antibody with minimal reactivity to human serum proteins for use in immunohistochemistry and western blotting assays.


Catalog Number: (103259-980)
Supplier: Southern Biotechnology
Description: The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid production of primitive hematopoietic progenitor cells. A variety of cytokines act synergistically with SCF to stimulate proliferation and differentiation of bone marrow progenitor cells. For example, SCF plus IL-7 can stimulate the combined myeloid and B cell differentiation of uncommitted hematopoietic progenitor cells. SCF/c-Kit also participates in erythropoiesis in both the bone marrow and spleen. Loss-of-function mutations for SCF/c-Kit lead to a variety of pleiotropic developmental defects while gain-of-function mutations can lead to constitutive activation of the kit receptor and links to cancer. Examples of the former are mast cell deficiency and severe macrocytic anemia while the latter mutation has been identified in mastocytomas.


Catalog Number: (100241-944)
Supplier: Southern Biotechnology
Description: Low Endotoxin/Azide Free Mouse IgG2b for use as a control in flow cytometry, immunohistochemistry, and in vitro assays and as a standard in ELISA.


Catalog Number: (100244-214)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgM-TRITC antibody for use in immunohistochemistry / immunocytochemistry assays.


Catalog Number: (100245-518)
Supplier: Southern Biotechnology
Description: Purified Anti-Chicken IgY antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, ELISA, and immunoprecipitation assays.


Catalog Number: (103265-160)
Supplier: Southern Biotechnology
Description: Alexa Fluor 647 Anti-Human IgM antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100243-756)
Supplier: Southern Biotechnology
Description: The TCRγδ heterodimer of the CD3/T cell receptor complex is clonotypic and consists of Ig-like variable and constant domains. It is expressed during thymopoiesis and on the small subpopulation of γδ TCR-expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are γδ+ and have limited receptor diversity. The TCRγδ heterodimer recognizes peptide antigen bound to MHC antigens and subsequent signal transduction mediated by the invariant chains leads to T cell activation. The monoclonal antibody UC7-13D5 is specific for the γδ heterodimer and plate-bound UC7-13D5 activates γδ TCR-bearing cells. This antibody does not react with αβ TCR-expressing T cells.


Catalog Number: (103259-834)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Mouse IgG3 antibody for use in ELISA assays.


Catalog Number: (100245-008)
Supplier: Southern Biotechnology
Description: Goat Anti-Hamster IgG(H+L)-PE antibody with minimal reactivity to mouse and rat proteins for use in flow cytometry assays.


Catalog Number: (100243-622)
Supplier: Southern Biotechnology
Description: CD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the transferrin receptor. It is essential for the growth of normal and neoplastic cells. It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and mitogens presumably reflecting the iron dependence of proliferation. Its expression declines with maturation and differentiation. CD71 plays a critical role in cell proliferation by controlling the supply of iron which is essential for many metabolic pathways through the binding and endocytosis of transferrin, the major iron-carrying protein. It may also be involved in signal transduction via its association with the T cell receptor ζ chain. The monoclonal antibody RI7217 inhibits cell proliferation in vitro.


Catalog Number: (100245-286)
Supplier: Southern Biotechnology
Description: Purified Donkey Anti-Rabbit IgG(H+L) antibody with minimal reactivity to human, mouse, and rat serum proteins for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100246-348)
Supplier: Southern Biotechnology
Description: CD71 is a 95 kDa type II heterodimeric transmembrane glycoprotein that is the receptor for transferrin. CD71 expression is very low on resting leukocytes but is upregulated upon activation. CD71 plays a critical role in cell proliferation by controlling the supply of iron which is essential for many metabolic pathways through the binding and endocytosis of transferrin.


Catalog Number: (100245-278)
Supplier: Southern Biotechnology
Description: Donkey Anti-Rat IgG(H+L)-AP antibody with minimal reactivity to mouse serum proteins for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100244-374)
Supplier: Southern Biotechnology
Description: Goat Anti-Human Lambda-TRITC antibody for use in immunohistochemistry / immunocytochemistry and western blotting assays.


Catalog Number: (103265-460)
Supplier: Southern Biotechnology
Description: ApoScreen® Annexin V (SB Cat. No. 10040) is a recombinant protein that is expressed in E. coli. A number of changes in cell structure occur during apoptosis. One major change is the loss of membrane phospholipid asymmetry, with translocation of phosphatidylserine (PS) from the inner leaflet of the phospholipid bilayer to the external surface. Annexin V, a member of the annexin family of calcium-dependent phospholipid binding proteins, has a high affinity for phosphatidylserine (PS)-containing phospholipid bilayers. Conjugated Annexin V can be used to monitor changes in cell membrane phospholipid asymmetry, thereby providing a convenient tool for detection of apoptotic cells.


Catalog Number: (103264-492)
Supplier: Southern Biotechnology
Description: AP Anti-Mouse IgG1 antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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