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Catalog Number: (100242-228)
Supplier: Southern Biotechnology
Description: Bcl-xL is a 29 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. It is found in both soluble and membrane fractions of cellular lysates. Like Bcl-2, Bcl-xL has been demonstrated to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. While formation of heterodimers with the apoptosis-enhancing protein, Bax does not block the apoptosis-suppressing property of Bcl-xL, heterodimerization with Bad effectively inhibits the protective function of Bcl-xL.


Catalog Number: (103259-820)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG2b-AP antibody with minimal reactivity to human, bovine, and horse serum proteins for use in ELISA, western blotting, and immunocytochemistry assays.


Catalog Number: (103264-198)
Supplier: Southern Biotechnology
Description: Rat IgG1-Pacific Blue for use as a control in flow cytometry assays.


Catalog Number: (100244-216)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgM-AP antibody for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.


Catalog Number: (100245-168)
Supplier: Southern Biotechnology
Description: Rabbit Anti-Mouse IgG(H+L)-HRP antibody for use in ELISA, immunohistochemistry, western blotting, and ELISpot assays.


Catalog Number: (101442-832)
Supplier: Southern Biotechnology
Description: CY5 Anti-Rat IgG2b antibody for use in flow cytometry, immunohistochemistry, and western blotting assays.


Catalog Number: (100242-112)
Supplier: Southern Biotechnology
Description: Low Endotoxin/Azide Free Rat IgG2b for use as a control in flow cytometry, immunohistochemistry, and in vivo assays and as a standard in ELISA.


Catalog Number: (103264-970)
Supplier: Southern Biotechnology
Description: Rabbit Anti-Human IgG(H+L)-PE antibody for use in flow cytometry assays.


Catalog Number: (100243-784)
Supplier: Southern Biotechnology
Description: The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the costimulatory molecule CD28 and both molecules share common B7 family counter-receptors. However CD152 is thought to be a negative regulator of T cell activation and may play a role in apoptotic control of T cells. CD152 is relatively conserved among humans, mice, and chickens.


Catalog Number: (100243-586)
Supplier: Southern Biotechnology
Description: CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes, and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN γ, IL-1, TNF-α, lipopolysaccharide, and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1.


Catalog Number: (100244-268)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgG-HRP antibody for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.


Catalog Number: (100243-466)
Supplier: Southern Biotechnology
Description: Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCRαβ+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B and T cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.


Catalog Number: (100244-126)
Supplier: Southern Biotechnology
Description: The monoclonal antibody 15-5-5 reacts with the H-2Dk class I alloantigen. It cross-reacts with H-2Kd and with cells from mice with the H-2f haplotype. The antibody does not react with other (e.g., a, b, p, q, r, s) haplotypes.


Supplier: Southern Biotechnology
Description: CD9 is a 24 kDa member of the transmembrane 4 superfamily (TM4-SF) of cell surface receptors. It is expressed strongly on platelets, lymphoid progenitor cells, activated lymphocytes and endothelia, and, weakly, on eosinophils, granulocytes, monocytes, and macrophages. CD9 functions as an adhesion molecule where it mediates platelet aggregation and activation.

Catalog Number: (103265-496)
Supplier: Southern Biotechnology
Description: FITC Anti-Mouse TNF-alpha antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100245-830)
Supplier: Southern Biotechnology
Description: PE Anti-Human IgG3 Hinge antibody for use in flow cytometry and multiplex assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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