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Catalog Number: (10049-612)
Supplier: Enzo Life Sciences
Description: DcR1 is a 65kDa GPI-anchored member of the TNFR superfamily (TNFRSF10C) also known as TRAIL-R3, TRID, CD263, and LIT. Although not expressed by most tumors, DcR1 is expressed at low levels on normal tissues, acting as a TRAIL decoy receptor, thus inhibiting apoptosis. DcR1 is termed a decoy receptor, as it does not have a functional death domain to induce apoptosis following TRAIL ligation.


Catalog Number: (76285-122)
Supplier: Enzo Life Sciences
Description: Recombinant monclonal antibody (Rat IgG2bκ).

Recommended Applications: Flow Cytometry, IHC


Catalog Number: (76285-126)
Supplier: Enzo Life Sciences
Description: Recombinant monclonal antibody (Human IgG1κ).

Recommended Applications: ELISA, IHC (FS), WB


Supplier: Enzo Life Sciences
Description: Hsp60 is a member of the chaperonin family of heat shock proteins, with homologs functioning in the cytosol and mitochondria to fold nascent and aggregated proteins. Hsp60 is the eukaryotic homolog of the E. coli GroEL protein, and forms a multimeric complex in the mitochondria with Hsp10 (Cpn10) to form a large central cavity in which ATP-dependent protein folding takes place. TRiC/CCT, a eukaryotic relative of Hsp60, is expressed in the cytosol and participates in the folding of actin and tubulin substrates, but lacks any association with an Hsp10-like co-factor.

Supplier: Enzo Life Sciences
Description: The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.

SDS

Supplier: Enzo Life Sciences
Description: Transferrin is a serum glycoprotein involved in iron transport. Transferrin exists in two forms, the iron-free Apotransferrin, which binds two Fe3+ ions to generate Ferrotransferrin. Apotransferrin remains tightly bound to its receptor until the complex is recycled to the cell surface, where Apotransferrin is released into the extracellular space to recruit more Fe3+ ions.

SDS

Catalog Number: (10049-568)
Supplier: Enzo Life Sciences
Description: Anti-GRP78 Rabbit Polyclonal Antibody


Catalog Number: (76201-832)
Supplier: Enzo Life Sciences
Description: Recombinant monoclonal antibody


Supplier: Enzo Life Sciences
Description: Ixabepilone is an epothilone B analog and nontaxane microtubule-stabilizing compound with clinical activity in a range of solid tumors

Catalog Number: (200060-572)
Supplier: Enzo Life Sciences
Description: HGF/SF (Hepatocyte growth factor/Scatter factor) is a multifunctional heterodimeric polypeptide. It mediates the growth and scattering of various cell types, epithelial mesenchymal transition, the formation of tubules and lumens, and promotes angiogenesis. The ligand-receptor pair has also shown to be uniquely involved in most human solid tumors and to participate in tumor development, invasion, and metastasis.


Catalog Number: (76002-566)
Supplier: Enzo Life Sciences
Description: Recommended Applications: IHC (PS), WB

Species reactivity: Human, Mouse


Catalog Number: (76002-582)
Supplier: Enzo Life Sciences
Description: Recommended Applications: ELISA, IHC, WB, FUNC

Species reactivity: Mammalian


Catalog Number: (76002-628)
Supplier: Enzo Life Sciences
Description: Recommended Applications: Flow Cytometry, IF

Species reactivity: Human


Supplier: Enzo Life Sciences
Description: Recommended Applications: ELISA, IHC, WB

Species reactivity: Human

Catalog Number: (76002-904)
Supplier: Enzo Life Sciences
Description: Recommended Applications: ELISA, Flow Cytometry, ICC, IF, IHC (PS), WB

Species reactivity: Human, Mouse, Rat, Yeast, Rabbit, Insect, Hamster, E. coli, Chicken


Catalog Number: (76529-708)
Supplier: Enzo Life Sciences
Description: Purified human IgE with kappa light chains produced <i>in vitro</i> from a monoclonal hybridoma.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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