Dynasore ≥98% (by NMR)
Supplier: SAFE AND SURE NEDERLAND B.V.
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270-502-M005
270-502-M025
89148-114EA
75.21
USD
89148-114
89148-116
Dynasore ≥98% (by NMR)
Dynasore
GTPase inhibitor
Small molecule GTPase inhibitor targeting Dynamin-1, Dynamin-2 and Drp1 (mitochondrial Dynamin). Noncompetitive inhibitor of Dynamin GTPase activity. Blocks Dynamin-dependent endocytosis in cells (including neurons). Fast acting (seconds). Strong, dose dependent block of the traffic and accumulation of transferrin with 80µM dynasore (IC50 = 15µM). Has also been shown to block human papillomavirus type 16 (HPV16) and bovine papillomavirus type 1 (BPV1) (pseudovirions) infections.
Formula:
C₁₈H₁₄N₂O₄ |
MDL Number:
MFCD00292551 CAS Number: 304448-55-3 |
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