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Catalog Number: (76003-474)
Supplier: Enzo Life Sciences
Description: Produced in E. coli.


Catalog Number: (10033-650)
Supplier: Enzo Life Sciences
Description: Ubiquitin-rhodamine is a high purity industry standard substrate for studying deubiquitinylating activity where detection sensitivity or continuous monitoring of activity.


Catalog Number: (10033-752)
Supplier: Enzo Life Sciences
Description: Designed to screen MMP-12 inhibitors using a quenched fluorogenic substrate.


Catalog Number: (10033-762)
Supplier: Enzo Life Sciences
Description: Bacterial lysate ideal for use as a broad positive control.


Catalog Number: (10033-540)
Supplier: Enzo Life Sciences
Description: High purity toxin with minimal lot-to-lot variation.

SDS


Catalog Number: (10033-526)
Supplier: Enzo Life Sciences
Description: This kit is ideal for reliable and accurate quantification of protein aggregation in solution.


Catalog Number: (10049-786)
Supplier: Enzo Life Sciences
Description: Optimized for the vacuum filtration of multi-well plates


Catalog Number: (10049-454)
Supplier: Enzo Life Sciences
Description: Immunoglobulin G (IgG) is an immunoglobulin monomer consisting of two (gamma) heavy chains and two light chains.  Each IgG molecule contains two antigen binding domains and a single effector (Fc) domain.


Supplier: Enzo Life Sciences
Description: The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

Supplier: Enzo Life Sciences
Description: Glycogen Synthase Kinase 3β (GSK-3β) is a unique serine/threonine kinase that is inactivated by phosphorylation. In response to insulin binding, PKB/AKT phosphorylates GSK-3β on serine 9, which prevents GSK-3β from phosphorylating glycogen synthase. Unphosphorylated glycogen synthase is active and able to synthesize glycogen. GSK-3β is also unique in that it requires a substrate that has been phosphorylated by a distinct kinase before it can phosphorylate the substrate. This phosphate priming mechanism explains why phosphorylation of serine 9 inactivates GSK-3β. The phosphorylated serine binds to the GSK-3β priming phosphate position and prevents binding of alternative substrates. In addition to insulin signaling, GSK-3β participates in the Wnt signaling pathway, where it forms a complex with axin, beta-catenin and adenomatous polyposis coli (APC) protein. In the presence of Wnts, GSK-3β is unable to phosphorylate beta-catenin, which leads to stabilization of beta-catenin. The Wnt pathway inactivates GSK-3β via the proteins, Dishevelled and FRAT, which disrupt the interaction of GSK-3β with axin, beta-catenin, and APC. Clinically, there is considerable interest in GSK-3β inhibitors because they may mimic the effect of insulin or reduce the hyperphosphorylation of Tau that is observed in Alzheimer's Disease.

Catalog Number: (76001-934)
Supplier: Enzo Life Sciences
Description: Produced in E. coli. Non-glycosylated protein, containing 71 amino acids.


Catalog Number: (76002-150)
Supplier: Enzo Life Sciences
Description: Recommended Applications: ELISA, Flow Cytometry, ICC, IF, IHC, IHC (FS), IHC (PS), IP, WB

Species reactivity: Human, Mouse, Rat, Sheep, Rabbit, Porcine, Monkey, Ferret, Bovine


Catalog Number: (10050-138)
Supplier: Enzo Life Sciences
Description: Phosphatidylinositol 3-kinase (PI3-K) is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol and related compounds at the 3


Catalog Number: (10033-628)
Supplier: Enzo Life Sciences
Description: Produced in E. coli. The N-terminus is fused with a His tag.


Catalog Number: (10051-938)
Supplier: Enzo Life Sciences
Description: 31472488


Catalog Number: (76002-240)
Supplier: Enzo Life Sciences
Description: Recommended Applications: IHC (FS), IHC (PS)

Species reactivity: Epstein-Barr virus


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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