You Searched For: PROSCI INCORPORATED

Catalog Number: (76012-518)

Supplier: Prosci

Description: PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.

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Catalog Number: (76759-070)

Supplier: Prosci

Description: Anti-WASF3 Rabbit Polyclonal Antibody

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Catalog Number: (77124-696)

Supplier: Prosci

Description: BRSK2 Peptide

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Catalog Number: (76758-696)

Supplier: Prosci

Description: Anti-STAT5B Rabbit Polyclonal Antibody

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Catalog Number: (10109-310)

Supplier: Prosci

Description: HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least eleven alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

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Catalog Number: (10748-398)

Supplier: Prosci

Description: XAF-1 Antibody: XAF-1 binds to XIAP, an inhibitor of caspases-3, -7, and -9, and triggers its relocation from the cytosol to the nucleus. Overexpression of XAF-1 results in the neutralization of XIAP's ability to inhibit cell death. XAF-1 is normally expressed in all adult and fetal tissues but was found to be present in very low levels in a variety of cancer cell lines. In contrast, XIAP levels have been shown to be high in a majority of cell lines. Low XAF-1 and high basal expression of XIAP may therefore play a critical role in maintaining survival of cancer cell lines. Both IFN-alpha2 and IFN-beta can induce XAF-1 mRNA in all cells examined but induction of XAF-1 protein (as observed by immunoblot analysis) was seen only in cell lines sensitive to the apoptotic effects of IFNs.

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Catalog Number: (76764-352)

Supplier: Prosci

Description: Anti-NEU3 Rabbit Polyclonal Antibody

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Catalog Number: (76753-618)

Supplier: Prosci

Description: Anti-RNH1 Rabbit Polyclonal Antibody

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Catalog Number: (89419-510)

Supplier: Prosci

Description: TRIM25 peptide is used for blocking the activity of TRIM25 antibody.

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Catalog Number: (76630-818)

Supplier: Prosci

Description: Anti-V5 Epitope Tag Recombinant Antibody [Clone: SV5-P-K]

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Catalog Number: (75789-176)

Supplier: Prosci

Description: Phosphomannomutase 2 (PMM2) is an enzyme that is a member of the highly variable methyltransferase superfamily

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Catalog Number: (76749-238)

Supplier: Prosci

Description: Anti-EEF1G Rabbit Polyclonal Antibody

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Catalog Number: (10068-078)

Supplier: Prosci

Description: Polyclonal, Host: Chicken, Species Reactivity: Human, Immunogen: Human transferrin mix peptides (aa30-41, aa292-303, aa431-422) as combined immunogens, Tested Applications: ELISA, Western blotting, Immuno histochemistry, Immunocytochemistry

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Catalog Number: (76194-682)

Supplier: Prosci

Description: PAX8 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins which contain a paired box domain, an octapeptide, and a paired-type homeodomain. The PAX gene family has an important role in the formation of tissues and organs during embryonic development and maintaining the normal function of some cells after birth. The PAX genes give instructions for making proteins that attach themselves to certain areas of DNA. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. PAX8 releases the hormones important for regulating growth, brain development, and metabolism. Also functions in very early stages of kidney organogenesis, the müllerian system, and the thymus. Additionally, PAX8 is expressed in the renal excretory system, epithelial cells of the endocervix, endometrium, ovary, Fallopian tube, seminal vesicle, epididymis, pancreatic islet cells and lymphoid cells. PAX8 and other transcription factors play a role in binding to DNA and regulating the genes that drive thyroid hormone synthesis (Tg, TPO, Slc5a5 and Tshr).<p>PAX8 (and PAX2) is one of the important regulators of urogenital system morphogenesis. They play a role in the specification of the first renal cells of the embryo and remain essential players throughout development. [Wiki]

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Catalog Number: (76757-936)

Supplier: Prosci

Description: Anti-SLC25A11 Rabbit Polyclonal Antibody

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Catalog Number: (10116-438)

Supplier: Prosci

Description: Polyclonal; Host: Goat; Immunogen: PHLDA2 antibody was raised against a 14 amino acid synthetic peptide near the C-Terminus of PHLDA2; Application: ELISA

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