You Searched For: PROSCI INCORPORATED

Catalog Number: (10105-120)

Supplier: Prosci

Description: Orphan nuclear receptor EAR-2 (NR2F6, V-erbA related protein EAR-2 ) is predicted to be a protein similar in primary structure to receptors for steroid hormones or thyroid hormone (T3).

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Catalog Number: (89416-660)

Supplier: Prosci

Description: NUP155 Antibody: The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. One protein in this assembly is the nucleoporin (NUP)-155, which is localized symmetrically to both the nucleoplasmic and cytoplasmic faces of the NPC. NUP155 has been reported to interact with both NUP35 and the mRNA export factor Gle1, but the functions of these interactions are still unknown. NUP155 has also been shown to be required for NPC assembly and nuclear envelope (NE) membrane fusion. NUP155 is recruited late in NE formation, suggesting that NUP155 defines an essential late step in NE assembly. NUP155 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP155 may be an important drug target in HIV treatment. At least two isoforms of NUP155 are known to exist.

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Catalog Number: (89417-776)

Supplier: Prosci

Description: BAPX1 Antibody: BAPX1 is the mammalian homolog of the Drosophila bagpipe homeobox gene and is expressed in the splanchnic mesoderm and embryonic skeleton. It is one of the earliest developmental markers for the sclerotome portion of the somite and the gut mesentery. BAPX1 is required for normal skeletal development; homozygous inactivating mutations in the BAPX1 gene result in spodylo-megaepiphyseal-metaphyseal dysplasia (SMMD). It has also been suggested to play a role in the proper development of the mammalian gut and is required for distal stomach development as part of a BARX1-dependent pathway.

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Catalog Number: (10069-612)

Supplier: Prosci

Description: Polyclonal, Host: Rabbit, Species Reactivity: Bacteria, Immunogen: Whole cells of P. pastoris, Tested Applications: Western blotting

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Catalog Number: (76762-170)

Supplier: Prosci

Description: Anti-GNAI2 Rabbit Polyclonal Antibody

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Catalog Number: (77129-908)

Supplier: Prosci

Description: Human Recombinant CX3CL1 Protein (from HEK293 Cells)

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Catalog Number: (77123-920)

Supplier: Prosci

Description: NOX3 Peptide

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Catalog Number: (89421-120)

Supplier: Prosci

Description: TGM5 peptide is used for blocking the activity of TGM5 antibody.

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Catalog Number: (76752-642)

Supplier: Prosci

Description: Anti-ITGB8 Rabbit Polyclonal Antibody

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Catalog Number: (10748-956)

Supplier: Prosci

Description: Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.

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Catalog Number: (76760-634)

Supplier: Prosci

Description: Anti-CGB7 Rabbit Polyclonal Antibody

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Catalog Number: (10115-162)

Supplier: Prosci

Description: Polyclonal, Host: Goat; Target Species: Human, Mouse; Immunogen: STK3 antibody was raised against a 13 amino acid synthetic peptide near the internal region of STK3; Applications: ELISA,Western blotting

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Catalog Number: (10764-530)

Supplier: Prosci

Description: The HI130 monoclonal antibody specifically reacts with the 180 kDa, 190 kDa, 205 kDa, and 220 kDa isoforms of the human leukocyte common antigen (LCA) CD45. It is expressed on lymphocytes, granulocytes, monocytes, thymocytes, and eosinophils, but not on mature erythrocytes, platelets, mature erythroid cells of bone marrow, and non-hematopoietic tissues. CD45 is essential for T cell activation and the tyrosine phosphatase activity of its intracellular region is integral for signal transduction.

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Catalog Number: (10100-376)

Supplier: Prosci

Description: The exact function of LOC400566 remains unknown.

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Catalog Number: (10068-576)

Supplier: Prosci

Description: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2, 6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

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Catalog Number: (10750-974)

Supplier: Prosci

Description: ATG9B Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG9B plays a role in autophagy and it's highly expressed in placenta and pituitary gland.

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