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Image Unavailable-75789-364

Human Recombinant MMP1 (from Cells)

Catalog Number: (75789-364)
Supplier: Prosci
Description: Matrix Metalloproteinase-1 (MMP-1) is expressed by fibroblasts, keratinocytes, endothelial cells, monocytes and macrophages. MMP1 contains several distinct domains: a prodomain that is cleaved upon activation, a catalytic domain containing the zinc binding site, a short hinge region, and a carboxyl terminal (hemopexin like) domain. MMP-1 can degrade a broad range of substrates including types I, II, III, VII, VIII, and X collagens as well as casein, gelatin, alpha1 antitrypsin, myelin basic protein, L-Selectin, pro-TNF, IL1, IGFBP3, IGFBP5, pro-MMP2, and pro-MMP9. A significant role of MMP1 is the degradation of fibrillar collagens in extracellular matrix remodeling, characterized by the cleavage of the interstitial collagen triple helix into 3/4, 1/4 fragments. MMP1 may also be involved in enzyme cascades, cytokine regulation and cell surface molecule modulation.
Image Unavailable-77130-546

REL Peptide

Catalog Number: (77130-546)
Supplier: Prosci
Description: REL Peptide
Image Unavailable-77129-934

NDUFS2 Peptide

Catalog Number: (77129-934)
Supplier: Prosci
Description: NDUFS2 Peptide
Image Unavailable-77126-450

Human Recombinant CD52 Protein (from HEK293 cells)

Catalog Number: (77126-450)
Supplier: Prosci
Description: Human Recombinant CD52 Protein (from HEK293 cells)
Image Unavailable-77131-156

Anti-Mouse Monoclonal Antibody [clone: [A-1]] (PE (Phycoerythrin))

Catalog Number: (77131-156)
Supplier: Prosci
Description: Anti-Mouse Monoclonal Antibody [clone: [A-1]] (PE (Phycoerythrin))
Image Unavailable-77131-652

Anti-Mouse Monoclonal Antibody [clone: [AV20]] (PE (Phycoerythrin))

Catalog Number: (77131-652)
Supplier: Prosci
Description: Anti-Mouse Monoclonal Antibody [clone: [AV20]] (PE (Phycoerythrin))
Image Unavailable-77121-024

Semaphorin 5A Peptide

Catalog Number: (77121-024)
Supplier: Prosci
Description: Semaphorin 5A Peptide
Image Unavailable-77131-056

NMNAT3 Peptide

Catalog Number: (77131-056)
Supplier: Prosci
Description: NMNAT3 Peptide
Image Unavailable-75788-760

Human Recombinant IFN alpha 2a (from E. coli)

Catalog Number: (75788-760)
Supplier: Prosci
Description: At least 23 different variants of IFN- alpha are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN- alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN- alpha subtypes only differ in their sequences by one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.
Product Image-89415-228

Anti-SIRPA Rabbit Polyclonal Antibody

Catalog Number: (89415-228)
Supplier: Prosci
Description: SIRP alpha Antibody: Protein tyrosine phosphatases (PTPases) SHP-1 and SHP-2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP-2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP-2 associated glycoprotein was recently cloned from human, rat, mouse and cattle by several labs and was designated SIRPalpha, SHPS-1, MyD-1, BIT and p84. SIRPalpha is a new gene family containing at least fifteen members. SIRPalpha is a substrate of many activated tyrosine kinases such as insulin receptor, EGFR, PDGFR and src, and a specific docking protein for SHP-2. SIRPalpha has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes.
Product Image-89417-136

Anti-JMJD2A Rabbit Polyclonal Antibody

Catalog Number: (89417-136)
Supplier: Prosci
Description: JMJD2A Antibody: Members of the Jumonji domain 2 (JMJD2) family contain a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. The first member of this group, JMJD2A, is widely expressed in human tissues and cell lines and functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. JMJD2A can also form a complex with the androgen receptor (AR), a transcription factor that is pivotal for the development of prostate cancer. Overexpression of JMJD2A stimulates AR function and this stimulation is dependent on JMJD2A catalytic activity, suggesting that JMJD2A might be a critical protein with roles in cell proliferation and oncogenesis.
Image Unavailable-77125-960

Anti-DPP4 Mouse Monoclonal Antibody [clone: [134-2C2]] (PE (Phycoerythrin))

Catalog Number: (77125-960)
Supplier: Prosci
Description: Anti-DPP4 Mouse Monoclonal Antibody [clone: [134-2C2]] (PE (Phycoerythrin))
Image Unavailable-77129-794

Anti-Il2 Rat Monoclonal Antibody [clone: [JES6-1A12]]

Catalog Number: (77129-794)
Supplier: Prosci
Description: Anti-Il2 Rat Monoclonal Antibody [clone: [JES6-1A12]]
Image Unavailable-10764-426

Anti-CD4 Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: RPA-T4]

Catalog Number: (10764-426)
Supplier: Prosci
Description: The RPA-T4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation, together with the MHC class II. The RPA-T4 antibody is capable of blocking HIV binding and inhibiting syncytium formation, by binding to the D1 domain of the CD4 antigen. The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.
Image Unavailable-76195-300

Anti-PGR Mouse Monoclonal Antibody [clone: SPM566]

Catalog Number: (76195-300)
Supplier: Prosci
Description: This mAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone.
Product Image-10070-150

Anti-CDK6 Rabbit Polyclonal Antibody

Catalog Number: (10070-150)
Supplier: Prosci
Description: Probably involved in the control of the cell cycle. Interacts with D-type G1 cyclins.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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