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Product Image-10108-716

Anti-MMP1 Rabbit Polyclonal Antibody

Catalog Number: (10108-716)
Supplier: Prosci
Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP1 is a secreted enzyme which breaks down the interstitial collagens, types I, II, and III.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Product Image-76009-424

Anti-PHTF2 Rabbit Polyclonal Antibody

Catalog Number: (76009-424)
Supplier: Prosci
Description: For WB starting dilution is: 1:1000
Product Image-10100-626

Anti-TRAF4 Rabbit Polyclonal Antibody

Catalog Number: (10100-626)
Supplier: Prosci
Description: TRAF4 is a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. It has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD (P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK.This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD (P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Image Unavailable-76749-462

Anti-ATP1A4 Rabbit Polyclonal Antibody

Catalog Number: (76749-462)
Supplier: Prosci
Description: Anti-ATP1A4 Rabbit Polyclonal Antibody
Image Unavailable-77132-704

Vimentin Peptide

Catalog Number: (77132-704)
Supplier: Prosci
Description: Vimentin Peptide
Product Image-10100-446

Anti-FBXO28 Rabbit Polyclonal Antibody

Catalog Number: (10100-446)
Supplier: Prosci
Description: Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
Image Unavailable-77125-302

Anti-MMP9 Mouse Monoclonal Antibody [clone: [SB15c]]

Catalog Number: (77125-302)
Supplier: Prosci
Description: Anti-MMP9 Mouse Monoclonal Antibody [clone: [SB15c]]
Image Unavailable-76630-342

Anti-ITGA2B Recombinant Antibody [Clone: BAG 75E5]

Catalog Number: (76630-342)
Supplier: Prosci
Description: Anti-ITGA2B Recombinant Antibody [Clone: BAG 75E5]
Product Image-10751-532

Anti-RUSC2 Rabbit Polyclonal Antibody

Catalog Number: (10751-532)
Supplier: Prosci
Description: RUSC2 Antibody: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.
Image Unavailable-76193-892

Anti-Phosphotyrosine Mouse Monoclonal Antibody [clone: PY20]

Catalog Number: (76193-892)
Supplier: Prosci
Description: Protein phosphorylation is a fundamental event in the regulation of a large number of intracellular processes. Phosphorylation of specific tyrosine residues is the result of activation or stimulation of their respective protein tyrosine kinases. The phosphorylated proteins can be auto-phosphorylated kinases or certain cellular protein substrates. Tyrosine-phosphorylated proteins are involved in signal transduction and in the regulation of cell proliferation. antibody to phosphotyrosine provides an excellent tool for the detection, characterization, and purification of phosphotyrosine containing proteins. This antibody shows no cross-reaction with other phosphoamino acids and is superb for multiple applications including staining of formalin/paraffin tissues.
Product Image-10070-264

Anti-SHC1 Rabbit Polyclonal Antibody

Catalog Number: (10070-264)
Supplier: Prosci
Description: Signaling adapter that couples activated growth factor receptors to signaling pathway. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span
Image Unavailable-10765-988

Anti-FOXP3 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: 3G3]

Catalog Number: (10765-988)
Supplier: Prosci
Description: Mouse Monoclonal Foxp3 Antibody [3G3] (PE), Isotype: IgG1, kappa, Application: FACS
Product Image-10103-500

Anti-INMT Rabbit Polyclonal Antibody

Catalog Number: (10103-500)
Supplier: Prosci
Description: N-methylation of endogenous and xenobiotic compounds is a major method by which they are degraded. This gene encodes an enzyme that N-methylates indoles such as tryptamine.N-methylation of endogenous and xenobiotic compounds is a major method by which they are degraded. This gene encodes an enzyme that N-methylates indoles such as tryptamine.
Product Image-10108-640

Anti-CYP2C9 Rabbit Polyclonal Antibody

Catalog Number: (10108-640)
Supplier: Prosci
Description: CYP2C9 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that CYP2C9 gene is polymorphic.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Image Unavailable-76764-718

Anti-CACNG4 Rabbit Polyclonal Antibody

Catalog Number: (76764-718)
Supplier: Prosci
Description: Anti-CACNG4 Rabbit Polyclonal Antibody
Image Unavailable-77127-964

EWS Peptide

Catalog Number: (77127-964)
Supplier: Prosci
Description: EWS Peptide
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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