You Searched For: PROSCI INCORPORATED

Catalog Number: (10114-202)

Supplier: Prosci

Description: Polyclonal, Host: Goat; Target Species: Human, mouse ; Immunogen: GAL antibody was raised against a 13 amino acid synthetic peptide near the internal region of GA; Applications: ELISA,Western blotting

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Catalog Number: (89417-870)

Supplier: Prosci

Description: TYW3 Antibody: TYW3 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.

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Catalog Number: (75791-962)

Supplier: Prosci

Description: Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) is a member of the tumor necrosis factor receptor superfamily. Human TNF RII contains four cysteinerich repeats in its ECD, which shares 58% and 56% amino acid sequence identity with the mouse and rat orthologs, respectively.TNF RII is expressed predominantly on cells of the hematopoietic lineage, such as T and natural killer cells, as well as on endothelial cells, microglia, astrocytes,neurons, oligodendrocytes, cardiac myocytes, thymocytes, and mesenchymal stem cells.TNF RII binds to the membranebound forms of TNF alpha and Lymphotoxin alpha/TNF beta ;soluble TNF is thought to signal predominately through TNF RI.Soluble TNF RII is believed to inhibit TNF biological activity by binding TNF thereby preventing it from activating membrane TNF receptors.

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Catalog Number: (10070-854)

Supplier: Prosci

Description: Polyclonal antibody E. coli-Biotin Host: Rabbit Species reactivity: Bacteria Tested application: WB immunogen Mixtures of all antigenic serotypes

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Catalog Number: (10109-260)

Supplier: Prosci

Description: SLC43A2 is a Sodium-, chloride, pH-independent high affinity transport of large neutral amino acids.

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Catalog Number: (76749-126)

Supplier: Prosci

Description: Anti-NSD2 Rabbit Polyclonal Antibody

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Catalog Number: (77126-558)

Supplier: Prosci

Description: Human Recombinant LILRB3 Protein (from HEK293 Cells)

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Catalog Number: (77120-970)

Supplier: Prosci

Description: HAT-tag Peptide [9A2F8]

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Catalog Number: (76009-388)

Supplier: Prosci

Description: This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq].

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Catalog Number: (89415-998)

Supplier: Prosci

Description: BMI-1 Antibody: The transcriptional repressor BMI-1 was first identified as a proto-oncogene frequently activated by Moloney murine leukemia proviral insertions in mice and cooperating with c-myc in the generation of mouse lymphomas. BMI-1 is involved in segment specification, cell growth and maintenance, transcriptional regulation, and chromatin modification. A major target of BMI-1 is the ink4a locus which encodes tumor suppressor proteins p16 and p19Arf, which are important in tumor progression and thought to be critical in cell proliferation and senescence. Recent studies have also shown that BMI-1 is required for the maintenance of adult normal and leukemic stem cells, suggesting that BMI-1 could an attractive therapeutic target for stem cell proliferation and renewal as well as for anti-cancer strategies.

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Catalog Number: (76195-800)

Supplier: Prosci

Description: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin. This antigen is also expressed on the surface of cells of myeloid lineage.

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Catalog Number: (10106-356)

Supplier: Prosci

Description: This gene, ZNF651, which is located on chromosome 3, is predicted to encode a zinc finger protein, currently with unknown fucntion.

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Catalog Number: (10102-602)

Supplier: Prosci

Description: TPPP3 belongs to the TPPP family. This protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. The function of TPPP3 remains unknown.

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Catalog Number: (10751-166)

Supplier: Prosci

Description: ZIP6 Antibody: The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.

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Catalog Number: (10116-256)

Supplier: Prosci

Description: Polyclonal antibody MAD2L1 Host: Goat Target Species: human immunogen: MAD2L1 antibody was raised against a 14 amino acid synthetic peptide near the C-Terminus of MAD2L1 Application: ELISA, WB, IF

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Catalog Number: (10100-476)

Supplier: Prosci

Description: The specific function of ARMC3 is not yet known.Armadillo/beta-catenin (CTNNB1; MIM 116806)-like (ARM) domains are imperfect 45-amino acid repeats involved in protein-protein interactions. ARM domain-containing proteins, such as ARMC3, function in signal transduction, development, cell adhesion and mobility, and tumor initiation and metastasis (Li et al., 2006 [PubMed 16915934]).

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