You Searched For: PROSCI INCORPORATED

Catalog Number: (10107-052)

Supplier: Prosci

Description: SMARCD2 is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein.The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein.

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Catalog Number: (10109-582)

Supplier: Prosci

Description: SHMT2 plays a role in interconversion of serine and glycine.

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Catalog Number: (10114-578)

Supplier: Prosci

Description: Polyclonal, Host: Goat; Target Species: Human; Immunogen: AIM2 antibody was raised against a 15 amino acid synthetic peptide near the C-Terminus of AIM2; Applications: ELISA,Western blotting

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Catalog Number: (77121-174)

Supplier: Prosci

Description: MPV17 Peptide

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Catalog Number: (76009-058)

Supplier: Prosci

Description: NDUFA11 encodes a subunit of the membrane-bound mitochondrial complex I. Complex I is composed of numerous subunits and functions as the NADH-ubiquinol reductase of the mitochondrial electron transport chain. Mutations in this gene are associated with severe mitochondrial complex I deficiency. Alternate splicing results in multiple transcript variants.

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Catalog Number: (10114-480)

Supplier: Prosci

Description: Polyclonal, Host: Goat; Target Species: Human; Immunogen: PAX1 antibody was raised against a 12 amino acid synthetic peptide near the internal region of PAX1 (aa 318-329); Applications: ELISA,Western blotting

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Catalog Number: (75791-394)

Supplier: Prosci

Description: Mouse myeloid cell surface antigen CD33(CD33) is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD33 contains one Ig-like C2-type domain and one Ig-like V-type domain. CD33 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 induces apoptosis in acute myeloid leukemia. CD33 is becoming increasingly important as a target of antibody-mediated therapy in acute myeloid leukaemia (AML).

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Catalog Number: (10106-570)

Supplier: Prosci

Description: FOXD1 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. FOXD1, specifically activate the 1b promoter of the RI alpha gene in testicular Sertoli cells.

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Catalog Number: (10102-726)

Supplier: Prosci

Description: TRIM49 contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein has been found to be preferentially expressed in testis.The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This gene has been found to be preferentially expressed in testis.

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Catalog Number: (10102-802)

Supplier: Prosci

Description: ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.

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Catalog Number: (89417-200)

Supplier: Prosci

Description: VARP Antibody: The VPS9 ankyrin repeat protein (VARP) binds to the Rab21, a guanine nucleotide exchange factor that plays an essential role in endocytic trafficking. VARP localizes to early endosomes and is thought to regulate endosome dynamics. VARP also interacts with TI-VAMP/VAMP7, a vesicular SNARE that mediates an exocytic pathway that is crucial to neurite growth. Depletion of VARP by RNA interference impairs neurite growth, suggesting that VARP is a positive regulator of neurite growth.

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Catalog Number: (10101-460)

Supplier: Prosci

Description: The function remains unknown.

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Catalog Number: (10115-806)

Supplier: Prosci

Description: Polyclonal antibody Coronin 3 Host: Goat Target Species: human immunogen: Coronin 3 antibody was raised against a 13 amino acid synthetic peptide near the C-Terminus of Coronin 3. Application: ELISA, WB

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Catalog Number: (76751-806)

Supplier: Prosci

Description: Anti-EPB41L2 Rabbit Polyclonal Antibody

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Catalog Number: (89418-314)

Supplier: Prosci

Description: PLAGL2 Antibody: The PLAG (Pleiomorphic adenoma gene) family of zinc finger proteins include PLAG1, ZAC1 and PLAG-like 2 (PLAGL2). PLAG1 is the target gene for the pleiomorphic adenomas of the salivary gland. ZAC1 (PLAGL1) concomitantly controls apoptosis and cell cycle arrest through separate pathways. ZAC1 also acts as a transcriptional cofactor for nuclear receptors. PLAGL2 belongs to the krueppel C2H2-type zinc-finger protein family and contains 6 C2H2-type zinc fingers. It functions as a positive regulator of transcription and localizes to the nucleus. PLAGL2 is ubiquitously expressed with particular abundance in spleen, lung and testis, where it may be involved in cell cycle arrest and apoptosis of tumor cells.

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Catalog Number: (10071-916)

Supplier: Prosci

Description: Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.

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