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Image Unavailable-77130-368

Anti-Ghrelin O-acyltransferase Goat Polyclonal Antibody

Catalog Number: (77130-368)
Supplier: Prosci
Description: Anti-Ghrelin O-acyltransferase Goat Polyclonal Antibody
Image Unavailable-77128-910

Rhesus Monkey Recombinant CD40 Protein (from HEK293 Cells)

Catalog Number: (77128-910)
Supplier: Prosci
Description: Rhesus Monkey Recombinant CD40 Protein (from HEK293 Cells)
Image Unavailable-77121-016

Human Recombinant Siglec-10 Protein (from HEK293 cells)

Catalog Number: (77121-016)
Supplier: Prosci
Description: Human Recombinant Siglec-10 Protein (from HEK293 cells)
Image Unavailable-77121-772

GRB2 Peptide

Catalog Number: (77121-772)
Supplier: Prosci
Description: GRB2 Peptide
Product Image-10748-526

Anti-ATF6 Rabbit Polyclonal Antibody

Catalog Number: (10748-526)
Supplier: Prosci
Description: ATF6 Antibody: Disruptions of protein folding and maturation in the endoplasmic reticulum (ER) result in the activation of the unfolded protein response (UPR), an integrated cellular signaling pathway that transmits information from the ER lumen to the cytoplasm and nucleus. Activating transcription factor 6 (ATF6) as well as the ER-transmembrane protein kinases IRE1p and PERK are the major transducers of the UPR. ATF6 is an ER transmembrane protein that is normally bound to the ER chaperone GRP78, but upon ER stress is released from GRP78 and proteolytically cleaved to yield a cytosolic fragment which then migrates to the nucleus, and together with the transcription factor XBP-1, activates transcription of UPR-responsive genes. ATF6 has two isoforms (ATF6alpha and ATF6beta ;); only ATF6alpha is recognized by this antibody.
Image Unavailable-76629-654

Anti-CD3E Recombinant Antibody [Clone: UCHT1]

Catalog Number: (76629-654)
Supplier: Prosci
Description: Anti-CD3E Recombinant Antibody [Clone: UCHT1]
Image Unavailable-77125-834

Anti-TOPAZ1 Rabbit Polyclonal Antibody

Catalog Number: (77125-834)
Supplier: Prosci
Description: Anti-TOPAZ1 Rabbit Polyclonal Antibody
Product Image-10764-308

Anti-CD3E Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: UCHT1]

Catalog Number: (10764-308)
Supplier: Prosci
Description: The UCHT1 monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains gamma, delta, and epsilon chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. Unlike HIT3a, another specific antibody of CD3, the UCHT1 antibody can stain both the surface and intracellular CD3 epsilon. The immobilized UCHT1 can cross-link with the TCR complex, enhancing cellular activation and proliferation.
Product Image-76010-728

Anti-MSH2 Rabbit Polyclonal Antibody

Catalog Number: (76010-728)
Supplier: Prosci
Description: MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. [provided by RefSeq].
Product Image-10751-496

Anti-SPATA18 Chicken Polyclonal Antibody

Catalog Number: (10751-496)
Supplier: Prosci
Description: SPATA18 Antibody: SPATA18, also known as SPETEX-1, was initially identified as a cytoplasmic protein of elongate spermatids that is thought to be involved in differentiation process of elongate spermatids to mature spermatozoa. Recent experiments have shown that SPATA18 is a transcriptional target of p53 and p63. It has also been suggested to play a role in mitochondria quality control by inducing intramitochondrial lysosome-like organella that eliminate oxidized mitochondrial proteins.
Product Image-76010-212

Anti-CCNG1 Rabbit Polyclonal Antibody

Catalog Number: (76010-212)
Supplier: Prosci
Description: The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq].
Product Image-10749-672

Anti-TSC2 Rabbit Polyclonal Antibody

Catalog Number: (10749-672)
Supplier: Prosci
Description: TSC2 Antibody: Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes. The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. TOR activity is stimulated by Rheb, a member of the Ras superfamily of G-proteins, when the GTP/GDP ratio bound to Rheb is high. Immunoprecipitated TSC1/TSC2 has been shown to stimulate Rheb GTPase activity in vitro, suggesting that the TSC1/TSC2 complex decreases the ability of Rheb to stimulate TOR activity. This is supported by experiments showing that overexpression of TSC1 and TSC2 results in a significant decrease in the GTP/GDP ratio bound to Rheb and the inhibition of cell growth. At least three isoforms of TSC2 exist.
Product Image-89415-592

Anti-PHAP Rabbit Polyclonal Antibody

Catalog Number: (89415-592)
Supplier: Prosci
Description: PHAP Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
Image Unavailable-76195-814

Anti-CHGA Mouse Monoclonal Antibody [clone: CHGA/765]

Catalog Number: (76195-814)
Supplier: Prosci
Description: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Product Image-10117-432

Anti-F2R Goat Polyclonal Antibody

Catalog Number: (10117-432)
Supplier: Prosci
Description: Polyclonal; Host: Goat; Species Reactiviy: Human; Immunogen: PAR1 antibody was raised against a 14 amino acid synthetic peptide near the Internal region (near N-Terminus) of PAR1; Application: ELISA, Western Blot
Image Unavailable-77121-470

GNB3 Peptide

Catalog Number: (77121-470)
Supplier: Prosci
Description: GNB3 Peptide
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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