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Catalog Number: (76749-278)
Supplier: Prosci
Description: Anti-NEK9 Rabbit Polyclonal Antibody


Catalog Number: (10105-122)
Supplier: Prosci
Description: NR2F6 is a nuclear orphan receptor that belongs to the COUP-TF subfamily


Catalog Number: (10103-420)
Supplier: Prosci
Description: STK16 is a protein kinase that acts on both serine and threonine residues.


Catalog Number: (76751-758)
Supplier: Prosci
Description: Anti-NTPCR Rabbit Polyclonal Antibody


Catalog Number: (77124-478)
Supplier: Prosci
Description: SMUG1 Peptide


Catalog Number: (76753-172)
Supplier: Prosci
Description: Anti-GUCA2A Rabbit Polyclonal Antibody


Catalog Number: (76759-078)
Supplier: Prosci
Description: Anti-CAST Rabbit Polyclonal Antibody


Catalog Number: (75791-960)
Supplier: Prosci
Description: Tumor necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surface protein belonging to the tumor necrosis factor receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. CD137 is expressed by mesenchymal cells, including endothelial cells, chondrocytes, and cells of the central nervous system. CD137 is also broadly expressed by cells of the human immune system, is broadly expressed by cells of the human immune system, including activated CD8+ and CD4+ T cells, activated natural killer (NK) cells, follicular dendritic cells (FDCs) and monocytes. CD137 has diverse roles in the immune response, the one key function is to promote the survival of both T cells and dendritic cells by binding the cognate ligand CD137L (4-1BBL).


Catalog Number: (10797-940)
Supplier: Prosci
Description: The very-low-density-lipoprotein receptor (VLDL-R) is a lipoprotein receptor that shows considerable similarity to the lowdensity-lipoprotein receptor. VLDL R is a 130 kDa type I transmembrane protein in the LDL receptor family that plays a significant role in lipid metabolism and in nervous system development and function .This receptor has been suggested to be important for the metabolism of apoprotein-E-containing triacylglycerol-rich lipoproteins, such as very-low-densitylipoprotein (VLDL), beta-migrating VLDL and intermediate-density lipoprotein. It is also one of the receptors of reelin, an extracellular matrix protein which regulates the processes of neuronal migration and synaptic plasticity. In humans, the VLDL-R is encoded by the VLDLR gene.
A rare neurological disorder first described in the 1970s under the name "disequilibrium syndrome" is now considered to be caused by the disruption of VLDLR gene. The disorder was renamed VLDLR-associated cerebellar hypoplasia (VLDLRCH) after a 2005 study. It is associated with parental consanguinity and found in secluded communities such as the Hutterites. VLDLRCH is one of the two known genetic disorders caused by a disruption of reelin signaling pathway, along with Norman-Roberts syndrome.


Catalog Number: (76010-130)
Supplier: Prosci
Description: Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets; central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.


Catalog Number: (10765-344)
Supplier: Prosci
Description: The Hit3a monoclonal antibody specifically reacts with the Epsilon chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The HIT3a antibody cross-links with the TCR complex, initiating the cellular activation and proliferation, but it cannot be used for intracellular CD3 staining, as it is able to stain only the surface CD3 complex.


Catalog Number: (10114-126)
Supplier: Prosci
Description: Polyclonal, Host: Goat, Species Reactivity: Mouse, Rat, Immunogen: MEST antibody was raised against a 14 amino acid synthetic peptide near the internal region of MEST, Tested Applications: ELISA, WB


Catalog Number: (10072-846)
Supplier: Prosci
Description: IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20R-α and type II IL-20R-β. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease. Recombinant human IL-20 is a 35.2 kDa homodimeric protein consisting of two 153 amino acid polypeptide chains.


Catalog Number: (10112-582)
Supplier: Prosci
Description: Polyclonal, Host: Goat, Species: Human, Immunogen: ETEA antibody was raised against a 13 amino acid synthetic peptide near the C-Terminus of ETEA, Application: ELISA, WIB


Catalog Number: (10105-286)
Supplier: Prosci
Description: A chromosomal aberration involving SUZ12 may be a cause of endometrial stromal tumors. Translocation t (7;17) (p15;q21) with JAZF1 generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer.This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. The specific function of this gene has not yet been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.


Catalog Number: (10106-316)
Supplier: Prosci
Description: ZNF559 is a new candidate transcription factor.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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